September 2018: adverse event reports that FDA received

Month in which FDA received the reports

Read this first. FDA says this about the data:

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another. When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event. This dataset should not be the sole source of information for clinical decision-making or other assumptions about the safety or effectiveness of a product. The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources.
FDA Center for Veterinary Medicine publishes these words. Source: Adverse Event Reports for Animal Drugs and Devices, read on 2 Oct 2026. The data have the reports that FDA received through 26 Jun 2026.

FDA received 6,100 adverse event reports for animal drugs in September 2018. It received 5,952 reports in September 2017. The average of the 12 months before September 2018 is 5,929 reports for each month.

Of the 6,100 reports, 76.7% are about dogs, 10.6% are about cats and 0.5% are about horses. The other reports are about other species, or give no species. A report is not proof that a drug caused a sign.

Search engines do not list month pages. The site keeps the page, and the list of months links it.

The months before and after

Reports for each month, Mar 2017 to Mar 2019. The column with the outline is September 2018.

Reports by species

Dog76.7%4,677
Cat10.6%647
Horse0.5%32
Other species, or species not given12.2%744

Drug pages with reports received in September 2018

The table has every drug page with 10 or more reports that FDA received in September 2018, in order of name. No count decides which drug is in the table. The table has 77 drug pages.

Show the 77 drug pages

Drug pages with 10 or more reports received in September 2018, in order of name
Active ingredients	Reports received in September 2018
(S) - methoprene	20
Afoxolaner	631
Amoxicillin	10
Amoxicillin Trihydrate + Clavulanate Potassium	32
Atipamezole Hydrochloride	10
Buprenorphine	28
Butorphanol Tartrate	20
Capromorelin	16
Carprofen	90
Cefovecin sodium	53
Cefpodoxime proxetil	17
Ceftiofur Crystalline Free Acid	11
Cephalexin	18
Cyclosporine	41
Deracoxib	27
Desoxycorticosterone Pivalate	36
Dexamethasone	23
Dexamethasone + Neomycin Sulfate + Thiabendazole	11
Dexmedetomidine hydrochloride	15
Diphenhydramine	26
Doxycycline	20
Emodepside + Praziquantel	37
Enalapril Maleate	16
Enrofloxacin	18
Estriol	12
Famotidine	14
Febantel + Praziquantel + Pyrantel Pamoate	41
Firocoxib	14
Florfenicol + Mometasone furoate + Terbinafine	31
Florfenicol + Terbinafine	27
Fluralaner	977
Furosemide	16
Gabapentin	37
Grapiprant	95
Imidacloprid	60
Imidacloprid + Moxidectin	149
Insulin	66
Isoflurane	19
Ivermectin	72
Ivermectin + Praziquantel + Pyrantel Pamoate	25
Ivermectin + Pyrantel Pamoate	876
Ketoconazole	12
Levothyroxine sodium	16
Lotilaner	83
Lufenuron + Milbemycin Oxime	144
Lufenuron + Milbemycin Oxime + Praziquantel	71
Maropitant	73
Melarsomine Dihydrochloride	88
Meloxicam	31
Metronidazole	18
Milbemycin Oxime	63
Milbemycin Oxime + Praziquantel	330
Milbemycin Oxime + Spinosad	628
Mirtazapine	13
Monensin	11
Moxidectin	187
Nitenpyram	189
Oclacitinib	224
Omeprazole	10
Phenobarbital	11
Pimobendan	32
Polysulfated Glycosaminoglycan	28
Praziquantel	26
Praziquantel + Pyrantel Pamoate	20
Prednisolone	15
Prednisone	68
Propofol	20
Pyrantel Pamoate	13
Robenacoxib	24
Sarolaner	334
Selamectin	164
Sodium Chloride	23
Spinosad	142
Telmisartan	18
Tramadol	17
Trilostane	80
Tulathromycin	16

The openFDA records give the value "MSK" for the brand name and for the manufacturer name of each drug. FDA says that MSK means "masked". So the site cannot count a report for a brand.

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another.
Commonly used products may have a higher number of reported adverse events due to the higher total number of animals being given the product.
FDA Center for Veterinary Medicine. Source: Adverse Event Reports for Animal Drugs and Devices

Signs that the reports of the month list

A sign is a coded term from the report. The words in brackets are a plain gloss of the term. The percentage is the share of the 6,100 reports of the month.

The sign that is in the largest number of the reports comes first.

Vomiting18.5%1,128 reports
Lethargy[unusually tired or inactive]8.9%543 reports
Lack of efficacy (ectoparasite) - flea[the product did not have the expected effect: fleas]6.2%381 reports
Seizure NOS[seizure, type not specified]6%367 reports
Lack of efficacy (endoparasite) - heartworm[the product did not have the expected effect: heartworm]5.6%343 reports
Diarrhoea[diarrhea]5.6%339 reports
Ineffective, hooks[legacy FDA term: the product did not have the expected effect (hooks)]5.4%332 reports
Lack of efficacy (flea)[the product did not have the expected effect: fleas]3.2%195 reports
Unpalatable[legacy FDA term: the animal would not take it]2.7%166 reports
Death2.6%161 reports
Death by euthanasia[the animal was euthanized]2.5%153 reports
Behavioural disorder NOS[behaviour change, type not specified]2.5%152 reports
Ataxia[unsteady, uncoordinated movement]2.5%151 reports
Anorexia[not eating]2.5%150 reports

Show the next 1 signs

Emesis (multiple)[vomiting more than once]2.4%145 reports

Ingredients, all combinations

The list has every active ingredient with 10 or more reports received in September 2018, in order of name. It has 77 ingredients.

Show the 77 ingredients

The same month in other years

Cite this page

Pet Drug Reports. September 2018: adverse event reports for animal drugs. https://petdrugreports.com/month/2018-09/ Source: FDA Center for Veterinary Medicine, openFDA Animal and Veterinary adverse event reports, export of 30 Oct 2026. Reports received through 26 Jun 2026.

Where the data come from

The counts come from the openFDA Animal and Veterinary adverse event files, export of 30 Oct 2026. The files have the reports that the FDA Center for Veterinary Medicine received through 26 Jun 2026. The files mask brand and manufacturer names. The site counts a drug by the active ingredients that each record gives, and gives no count to a brand, an application or a company. Ingredient names and the lists of approved products follow the FDA Green Book of 2 Nov 2026. The month is the month in which FDA received the report, not the month of the event.

The site does not publish report text, lot numbers or details of a reporter. FDA's record is the authority. See how the site counts reports, the data sources and the corrections page.

Questions about this month

Can the count for September 2018 change?: Yes. FDA says that a report can take 3 to 6 months to reach the public data. The newest months can get more reports in a later update.
Does the month show when the event occurred?: No. The month is the month in which FDA received the report. The event can be from an earlier month.
Which sign is in the largest number of the reports of the month?: "Vomiting" is in 1,128 reports of the 6,100 reports of September 2018 (18.5%).