June 2022: adverse event reports that FDA received

Month in which FDA received the reports

Read this first. FDA says this about the data:

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another. When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event. This dataset should not be the sole source of information for clinical decision-making or other assumptions about the safety or effectiveness of a product. The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources.
FDA Center for Veterinary Medicine publishes these words. Source: Adverse Event Reports for Animal Drugs and Devices, read on 2 Oct 2026. The data have the reports that FDA received through 26 Jun 2026.

FDA received 4,560 adverse event reports for animal drugs in June 2022. It received 6,032 reports in June 2021. The average of the 12 months before June 2022 is 5,006 reports for each month.

Of the 4,560 reports, 77.1% are about dogs, 9.6% are about cats and 0.8% are about horses. The other reports are about other species, or give no species. A report is not proof that a drug caused a sign.

Search engines do not list month pages. The site keeps the page, and the list of months links it.

The months before and after

Reports for each month, Dec 2020 to Dec 2022. The column with the outline is June 2022.

Reports by species

Dog77.1%3,517
Cat9.6%439
Horse0.8%36
Other species, or species not given12.5%568

Drug pages with reports received in June 2022

The table has every drug page with 10 or more reports that FDA received in June 2022, in order of name. No count decides which drug is in the table. The table has 68 drug pages.

Show the 68 drug pages

Drug pages with 10 or more reports received in June 2022, in order of name
Active ingredients	Reports received in June 2022
(S) - methoprene	17
Afoxolaner	317
Amoxicillin Trihydrate + Clavulanate Potassium	24
Buprenorphine	11
Butorphanol Tartrate	26
Capromorelin	22
Carprofen	52
Cefovecin sodium	43
Cefpodoxime proxetil	11
Ceftiofur Crystalline Free Acid	11
Clotrimazole + Gentamicin	17
Cyclosporine	40
Dexamethasone	11
Dexmedetomidine	14
Dexmedetomidine hydrochloride	18
Diphenhydramine	17
Doxycycline	17
Emodepside + Praziquantel	22
Febantel + Praziquantel + Pyrantel Pamoate	34
Fenbendazole	14
Firocoxib	10
Florfenicol + Mometasone furoate + Terbinafine	34
Fluralaner	602
Fluralaner + Moxidectin	66
Gabapentin	34
Grapiprant	45
Imidacloprid	71
Imidacloprid + Moxidectin	43
Insulin	40
Isoflurane	15
Ivermectin	31
Ivermectin + Praziquantel + Pyrantel Pamoate	11
Ivermectin + Pyrantel Pamoate	527
Ketamine Hydrochloride	11
Levothyroxine sodium	11
Lotilaner	139
Lufenuron + Milbemycin Oxime	57
Lufenuron + Milbemycin Oxime + Praziquantel	72
Maropitant	57
Melarsomine Dihydrochloride	45
Meloxicam	25
Milbemycin Oxime	28
Milbemycin Oxime + Praziquantel	262
Milbemycin Oxime + Spinosad	134
Mirtazapine	12
Moxidectin	295
Moxidectin + Pyrantel Pamoate + Sarolaner	10
Nitenpyram	81
Oclacitinib	120
Omeprazole	14
Pimobendan	38
Polysulfated Glycosaminoglycan	28
Praziquantel	15
Praziquantel + Pyrantel Pamoate	17
Prednisolone	10
Prednisone	41
Propofol	14
Pyrantel Pamoate	17
Pyrantel Pamoate + Sarolaner	875
Robenacoxib	11
Sarolaner	119
Sarolaner + Selamectin	89
Selamectin	79
Sodium Chloride	31
Spinosad	22
Tigilanol tiglate	17
Trilostane	46
Verdinexor	12

The openFDA records give the value "MSK" for the brand name and for the manufacturer name of each drug. FDA says that MSK means "masked". So the site cannot count a report for a brand.

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another.
Commonly used products may have a higher number of reported adverse events due to the higher total number of animals being given the product.
FDA Center for Veterinary Medicine. Source: Adverse Event Reports for Animal Drugs and Devices

Signs that the reports of the month list

A sign is a coded term from the report. The words in brackets are a plain gloss of the term. The percentage is the share of the 4,560 reports of the month.

The sign that is in the largest number of the reports comes first.

Vomiting16.1%734 reports
Lack of efficacy (endoparasite) - heartworm[the product did not have the expected effect: heartworm]10.3%470 reports
Lethargy[unusually tired or inactive]9.1%415 reports
Lack of efficacy (ectoparasite) - flea[the product did not have the expected effect: fleas]6.6%303 reports
Lack of efficacy (endoparasite) - hookworm[the product did not have the expected effect: hookworms]6.3%287 reports
Lack of efficacy (ectoparasite) - tick NOS[the product did not have the expected effect: ticks]5.9%267 reports
Diarrhoea[diarrhea]5.4%244 reports
Seizure NOS[seizure, type not specified]4.9%223 reports
Lack of efficacy (bacteria) - Borrelia[the product did not have the expected effect: Borrelia (Lyme disease bacteria)]3.4%154 reports
Death2.8%127 reports
Not eating2.3%106 reports
Lack of efficacy (endoparasite) - roundworm NOS[the product did not have the expected effect: roundworms]2.1%97 reports
Emesis (multiple)[vomiting more than once]2.1%94 reports
Ataxia[unsteady, uncoordinated movement]1.9%86 reports

Show the next 1 signs

Decreased appetite1.9%86 reports

Ingredients, all combinations

The list has every active ingredient with 10 or more reports received in June 2022, in order of name. It has 64 ingredients.

Show the 64 ingredients

The same month in other years

Cite this page

Pet Drug Reports. June 2022: adverse event reports for animal drugs. https://petdrugreports.com/month/2022-06/ Source: FDA Center for Veterinary Medicine, openFDA Animal and Veterinary adverse event reports, export of 30 Oct 2026. Reports received through 26 Jun 2026.

Where the data come from

The counts come from the openFDA Animal and Veterinary adverse event files, export of 30 Oct 2026. The files have the reports that the FDA Center for Veterinary Medicine received through 26 Jun 2026. The files mask brand and manufacturer names. The site counts a drug by the active ingredients that each record gives, and gives no count to a brand, an application or a company. Ingredient names and the lists of approved products follow the FDA Green Book of 2 Nov 2026. The month is the month in which FDA received the report, not the month of the event.

The site does not publish report text, lot numbers or details of a reporter. FDA's record is the authority. See how the site counts reports, the data sources and the corrections page.

Questions about this month

Can the count for June 2022 change?: Yes. FDA says that a report can take 3 to 6 months to reach the public data. The newest months can get more reports in a later update.
Does the month show when the event occurred?: No. The month is the month in which FDA received the report. The event can be from an earlier month.
Which sign is in the largest number of the reports of the month?: "Vomiting" is in 734 reports of the 4,560 reports of June 2022 (16.1%).