June 2023: adverse event reports that FDA received

Month in which FDA received the reports

Read this first. FDA says this about the data:

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another. When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event. This dataset should not be the sole source of information for clinical decision-making or other assumptions about the safety or effectiveness of a product. The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources.
FDA Center for Veterinary Medicine publishes these words. Source: Adverse Event Reports for Animal Drugs and Devices, read on 2 Oct 2026. The data have the reports that FDA received through 26 Jun 2026.

FDA received 6,148 adverse event reports for animal drugs in June 2023. It received 4,560 reports in June 2022. The average of the 12 months before June 2023 is 5,039 reports for each month.

Of the 6,148 reports, 72.3% are about dogs, 15.8% are about cats and 0.8% are about horses. The other reports are about other species, or give no species. A report is not proof that a drug caused a sign.

Search engines do not list month pages. The site keeps the page, and the list of months links it.

The months before and after

Reports for each month, Dec 2021 to Dec 2023. The column with the outline is June 2023.

Reports by species

Dog72.3%4,443
Cat15.8%969
Horse0.8%52
Other species, or species not given11.1%684

Drug pages with reports received in June 2023

The table has every drug page with 10 or more reports that FDA received in June 2023, in order of name. No count decides which drug is in the table. The table has 82 drug pages.

Show the 82 drug pages

Drug pages with 10 or more reports received in June 2023, in order of name
Active ingredients	Reports received in June 2023
(S) - methoprene	27
Acepromazine Maleate	14
Afoxolaner	498
Amoxicillin + Clavulanate Potassium	11
Amoxicillin Trihydrate + Clavulanate Potassium	18
Atipamezole Hydrochloride	19
Benazepril hydrochloride + Spironolactone	13
Bexagliflozin	74
Buprenorphine	114
Butorphanol Tartrate	40
Capromorelin	30
Carprofen	80
Cefovecin sodium	62
Cyclosporine	40
Dexamethasone	16
Dexmedetomidine	16
Dexmedetomidine hydrochloride	19
Diphenhydramine	25
Doxycycline	27
Emodepside + Praziquantel	20
Enrofloxacin	22
Eprinomectin + Esafoxolaner + Praziquantel	39
Estriol	13
Famotidine	14
Febantel + Praziquantel + Pyrantel Pamoate	40
Firocoxib	14
Florfenicol + Mometasone furoate + Terbinafine	56
Fluralaner	743
Fluralaner + Moxidectin	83
Frunevetmab	208
Furosemide	17
Gabapentin	83
Grapiprant	56
Hydromorphone	13
Imidacloprid	71
Imidacloprid + Moxidectin	61
Insulin	61
Isoflurane	28
Ivermectin	35
Ivermectin + Pyrantel Pamoate	659
Ketamine Hydrochloride	22
Ketoconazole	12
Levothyroxine sodium	14
Lotilaner	172
Lufenuron + Milbemycin Oxime	40
Lufenuron + Milbemycin Oxime + Praziquantel	69
Maropitant	96
Melarsomine Dihydrochloride	58
Meloxicam	34
Methimazole	15
Metronidazole	20
Midazolam	19
Milbemycin Oxime	30
Milbemycin Oxime + Praziquantel	289
Milbemycin Oxime + Spinosad	129
Mirtazapine	10
Moxidectin	414
Moxidectin + Pyrantel Pamoate + Sarolaner	15
Nitenpyram	155
Oclacitinib	130
Omeprazole	24
Pergolide mesylate	12
Pimobendan	67
Polysulfated Glycosaminoglycan	22
Praziquantel	34
Praziquantel + Pyrantel Pamoate	26
Prednisolone	22
Prednisone	65
Propofol	25
Pyrantel Pamoate	12
Pyrantel Pamoate + Sarolaner	1,103
Robenacoxib	39
Sarolaner	152
Sarolaner + Selamectin	125
Selamectin	94
Sodium Chloride	55
Spinosad	13
Tigilanol tiglate	34
Trazodone	11
Trilostane	51
Tulathromycin	11
Verdinexor	12

The openFDA records give the value "MSK" for the brand name and for the manufacturer name of each drug. FDA says that MSK means "masked". So the site cannot count a report for a brand.

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another.
Commonly used products may have a higher number of reported adverse events due to the higher total number of animals being given the product.
FDA Center for Veterinary Medicine. Source: Adverse Event Reports for Animal Drugs and Devices

Signs that the reports of the month list

A sign is a coded term from the report. The words in brackets are a plain gloss of the term. The percentage is the share of the 6,148 reports of the month.

The sign that is in the largest number of the reports comes first.

Vomiting14.5%893 reports
Lack of efficacy (ectoparasite) - tick NOS[the product did not have the expected effect: ticks]9%552 reports
Lack of efficacy (endoparasite) - heartworm[the product did not have the expected effect: heartworm]8.8%538 reports
Lack of efficacy (ectoparasite) - flea[the product did not have the expected effect: fleas]8.6%527 reports
Lethargy[unusually tired or inactive]7.5%463 reports
Diarrhoea[diarrhea]6%367 reports
Lack of efficacy (endoparasite) - hookworm[the product did not have the expected effect: hookworms]6%366 reports
Seizure NOS[seizure, type not specified]4.4%272 reports
Lack of efficacy (bacteria) - Borrelia[the product did not have the expected effect: Borrelia (Lyme disease bacteria)]3.9%237 reports
Lack of efficacy (bacteria) - NOS[the product did not have the expected effect: target not specified]3%184 reports
Not eating2.7%164 reports
Lack of efficacy (endoparasite) - tapeworm[the product did not have the expected effect: tapeworms]2.3%144 reports
Death2.3%142 reports
Behavioural disorder NOS[behaviour change, type not specified]2.2%138 reports

Show the next 1 signs

Lack of efficacy (endoparasite) - roundworm NOS[the product did not have the expected effect: roundworms]2.1%132 reports

Ingredients, all combinations

The list has every active ingredient with 10 or more reports received in June 2023, in order of name. It has 80 ingredients.

Show the 80 ingredients

The same month in other years

Cite this page

Pet Drug Reports. June 2023: adverse event reports for animal drugs. https://petdrugreports.com/month/2023-06/ Source: FDA Center for Veterinary Medicine, openFDA Animal and Veterinary adverse event reports, export of 30 Oct 2026. Reports received through 26 Jun 2026.

Where the data come from

The counts come from the openFDA Animal and Veterinary adverse event files, export of 30 Oct 2026. The files have the reports that the FDA Center for Veterinary Medicine received through 26 Jun 2026. The files mask brand and manufacturer names. The site counts a drug by the active ingredients that each record gives, and gives no count to a brand, an application or a company. Ingredient names and the lists of approved products follow the FDA Green Book of 2 Nov 2026. The month is the month in which FDA received the report, not the month of the event.

The site does not publish report text, lot numbers or details of a reporter. FDA's record is the authority. See how the site counts reports, the data sources and the corrections page.

Questions about this month

Can the count for June 2023 change?: Yes. FDA says that a report can take 3 to 6 months to reach the public data. The newest months can get more reports in a later update.
Does the month show when the event occurred?: No. The month is the month in which FDA received the report. The event can be from an earlier month.
Which sign is in the largest number of the reports of the month?: "Vomiting" is in 893 reports of the 6,148 reports of June 2023 (14.5%).