June 1998: adverse event reports received

716 reports in the openFDA release of 28 Sep 2026

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An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another. When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event. This dataset should not be the sole source of information for clinical decision-making or other assumptions about the safety or effectiveness of a product. The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources. FDA Center for Veterinary Medicine

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716reports received

413same month a year earlier+73%

476monthly average, preceding 12 months

57.4%concern dogscats 8.7%

FDA's database holds 716 adverse event reports received in June 1998, against 413 in the same month a year earlier and a monthly average of 476 over the preceding 12 months.

57.4% of the month's reports concern dogs, 8.7% cats and 12.2% horses; the rest concern other species, exposed people, or give no species.

By active ingredient, the drugs named most often were selegiline hydrochloride (215), moxidectin (129) and ketamine hydrochloride (43), and the terms listed most often were lack of efficacy - NOS (116), depression (81) and vomiting (70). Report volume has a seasonal shape, with more reports in the warmer months when parasite products are in heavier use.

The months around it

Drugs named most often, by active ingredient

Active ingredients recorded for the drug	Reports	Share of the month's reports
Selegiline Hydrochloride	215	30%
Moxidectin	129	18%
Ketamine Hydrochloride	43	6%
Diethylcarbamazine Citrate	32	4.5%
Pentobarbital	28	3.9%
Lufenuron + Milbemycin Oxime	23	3.2%
Melarsomine Dihydrochloride	17	2.4%
Tiletamine Hydrochloride + Zolazepam Hydrochloride	17	2.4%
Lufenuron	16	2.2%
Pyrantel Pamoate	15	2.1%
Carprofen	14	2%
Ivermectin	14	2%
Griseofulvin	11	1.5%
Ivermectin + Pyrantel Pamoate	11	1.5%
Orbifloxacin	11	1.5%

Ordered by report count, which follows how widely each drug was in use. FDA states that these data cannot be used to estimate risk or to compare one product with another. Brand and manufacturer names are masked by FDA in these records.

Signs listed most often

Lack of efficacy - NOS[the product did not have the expected effect]16.2%116
Depression[dull, quiet or withdrawn]11.3%81
Vomiting9.8%70
Death8.8%63
Diarrhoea[diarrhea]6.6%47
Anorexia[not eating]6.4%46
Vials, Leaking[a product quality report, not a sign in an animal]5.7%41
Ataxia[unsteady, uncoordinated movement]5.3%38
Locking Mechanism Abnormal3.8%27
Accidental exposure[exposure that was not intended]3.4%24
Death by euthanasia[the animal was euthanized]3.4%24
Seal, Abnormal[a product quality report, not a sign in an animal]3.4%24
Fever3.2%23
Ineffective, anesthesia[legacy FDA term: the product did not have the expected effect (anesthesia)]2.9%21
No sign[no clinical sign was reported]2.9%21

Single ingredients, pooled

Selegiline Hydrochloride30%215

Moxidectin18%129

Ketamine Hydrochloride6%43

Lufenuron5.4%39

Diethylcarbamazine Citrate4.5%32

Milbemycin Oxime3.9%28

Pentobarbital3.9%28

Pyrantel Pamoate3.6%26

Ivermectin3.5%25

Melarsomine Dihydrochloride2.4%17

Tiletamine Hydrochloride2.4%17

Zolazepam Hydrochloride2.4%17

Species

Dog57.4%411

Cat8.7%62

Horse12.2%87

Other or not given21.8%156

Questions about June 1998

How many animal drug adverse event reports did FDA receive in June 1998?

716 reports are in the openFDA release of 28 Sep 2026. The same month a year earlier has 413.

Which drugs were named most often?

By active ingredient: selegiline hydrochloride (215), moxidectin (129), ketamine hydrochloride (43), diethylcarbamazine citrate (32) and pentobarbital (28). Brands are masked in the public data.

Which signs were listed most often?

lack of efficacy - NOS (116), depression (81), vomiting (70), death (63) and diarrhoea (47).

Can the count for a month still change?

Yes. FDA posts reports quarterly with a delay of three to six months, so the newest months are incomplete and usually grow in later releases. Older months change little.

Does a busy month mean something went wrong that month?

Not by itself. The date is when FDA received the report, not when the event happened, and volume follows season, product launches and publicity. FDA states that "there is no certainty that the reported drug or device caused the adverse event" and that the event "may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources."

Where this comes from. Counts are built from the openFDA Animal & Veterinary adverse event bulk files released 28 Sep 2026, which hold reports FDA's Center for Veterinary Medicine received through 31 Mar 2026. openFDA masks brand and manufacturer names in these files, so drugs are counted by the active ingredients each record discloses and no figure is attributed to a brand, application or company. Ingredient names, and the separate reference lists of approved products, follow the FDA Green Book as of 30 Sep 2026. The month is the date FDA first received the report, not the date of the event. No report text, lot numbers or reporter details are published. See the methodology and sources; FDA's record is authoritative, and corrections are handled within five working days.