July 2021: adverse event reports that FDA received

Month in which FDA received the reports

Read this first. FDA says this about the data:

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another. When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event. This dataset should not be the sole source of information for clinical decision-making or other assumptions about the safety or effectiveness of a product. The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources.
FDA Center for Veterinary Medicine publishes these words. Source: Adverse Event Reports for Animal Drugs and Devices, read on 2 Oct 2026. The data have the reports that FDA received through 26 Jun 2026.

FDA received 6,078 adverse event reports for animal drugs in July 2021. It received 6,509 reports in July 2020. The average of the 12 months before July 2021 is 5,540 reports for each month.

Of the 6,078 reports, 76.9% are about dogs, 9.9% are about cats and 1.1% are about horses. The other reports are about other species, or give no species. A report is not proof that a drug caused a sign.

Search engines do not list month pages. The site keeps the page, and the list of months links it.

The months before and after

Reports for each month, Jan 2020 to Jan 2022. The column with the outline is July 2021.

Reports by species

Dog76.9%4,675
Cat9.9%600
Horse1.1%66
Other species, or species not given12.1%737

Drug pages with reports received in July 2021

The table has every drug page with 10 or more reports that FDA received in July 2021, in order of name. No count decides which drug is in the table. The table has 85 drug pages.

Show the 85 drug pages

Drug pages with 10 or more reports received in July 2021, in order of name
Active ingredients	Reports received in July 2021
(S) - methoprene	24
Acepromazine Maleate	11
Afoxolaner	466
Amoxicillin Trihydrate + Clavulanate Potassium	19
Betamethasone Acetate + Florfenicol + Terbinafine	14
Buprenorphine	22
Butorphanol Tartrate	45
Capromorelin	30
Carprofen	74
Cefovecin sodium	42
Cefpodoxime proxetil	19
Cephalexin	16
Ciclesonide	13
Cyclosporine	30
Deracoxib	17
Desoxycorticosterone Pivalate	12
Dexamethasone	12
Dexmedetomidine	19
Dexmedetomidine hydrochloride	25
Diphenhydramine	36
Doxycycline	26
Emodepside + Praziquantel	23
Enalapril Maleate	15
Enrofloxacin	31
Eprinomectin + Praziquantel	10
Famotidine	11
Febantel + Praziquantel + Pyrantel Pamoate	66
Fenbendazole	16
Florfenicol + Mometasone furoate + Terbinafine	42
Fluralaner	733
Fluralaner + Moxidectin	37
Furosemide	15
Gabapentin	43
Gentamicin Sulfate + Hydrocortisone aceponate + Miconazole Nitrate	16
Grapiprant	53
Imidacloprid	63
Imidacloprid + Moxidectin	101
Insulin	63
Isoflurane	22
Ivermectin	49
Ivermectin + Praziquantel + Pyrantel Pamoate	13
Ivermectin + Pyrantel Pamoate	854
Ketamine Hydrochloride	21
Ketoconazole	13
Levothyroxine sodium	10
Lotilaner	176
Lufenuron + Milbemycin Oxime	85
Lufenuron + Milbemycin Oxime + Praziquantel	80
Maropitant	70
Melarsomine Dihydrochloride	95
Meloxicam	39
Metronidazole	17
Midazolam	15
Milbemycin Oxime	48
Milbemycin Oxime + Praziquantel	360
Milbemycin Oxime + Spinosad	275
Mirtazapine	18
Monensin	22
Moxidectin	420
Moxidectin + Pyrantel Pamoate + Sarolaner	15
Nitenpyram	165
Oclacitinib	137
Omeprazole	18
Pergolide mesylate	13
Phenobarbital	10
Pimobendan	27
Polysulfated Glycosaminoglycan	26
Praziquantel	31
Praziquantel + Pyrantel Pamoate	34
Prednisolone	15
Prednisone	51
Propofol	16
Pyrantel Pamoate	23
Pyrantel Pamoate + Sarolaner	678
Robenacoxib	12
Sarolaner	166
Sarolaner + Selamectin	138
Selamectin	114
Sodium Chloride	38
Spinosad	52
Tigilanol tiglate	41
Tramadol	11
Trazodone	12
Trilostane	70
Tulathromycin	11

The openFDA records give the value "MSK" for the brand name and for the manufacturer name of each drug. FDA says that MSK means "masked". So the site cannot count a report for a brand.

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another.
Commonly used products may have a higher number of reported adverse events due to the higher total number of animals being given the product.
FDA Center for Veterinary Medicine. Source: Adverse Event Reports for Animal Drugs and Devices

Signs that the reports of the month list

A sign is a coded term from the report. The words in brackets are a plain gloss of the term. The percentage is the share of the 6,078 reports of the month.

The sign that is in the largest number of the reports comes first.

Vomiting16.3%992 reports
Lack of efficacy (endoparasite) - heartworm[the product did not have the expected effect: heartworm]10.6%642 reports
Lethargy[unusually tired or inactive]8.4%510 reports
Lack of efficacy (ectoparasite) - flea[the product did not have the expected effect: fleas]8.1%495 reports
Lack of efficacy (endoparasite) - hookworm[the product did not have the expected effect: hookworms]7.7%467 reports
Diarrhoea[diarrhea]6.5%393 reports
Seizure NOS[seizure, type not specified]3.5%215 reports
Lack of efficacy - NOS[the product did not have the expected effect]2.9%178 reports
Lack of efficacy (ectoparasite) - tick NOS[the product did not have the expected effect: ticks]2.6%156 reports
Death2.5%154 reports
Not eating2.2%135 reports
Anorexia[not eating]2.2%131 reports
Emesis (multiple)[vomiting more than once]2.1%128 reports
Ataxia[unsteady, uncoordinated movement]2.1%126 reports

Show the next 1 signs

Decreased appetite2.1%125 reports

Ingredients, all combinations

The list has every active ingredient with 10 or more reports received in July 2021, in order of name. It has 83 ingredients.

Show the 83 ingredients

The same month in other years

Cite this page

Pet Drug Reports. July 2021: adverse event reports for animal drugs. https://petdrugreports.com/month/2021-07/ Source: FDA Center for Veterinary Medicine, openFDA Animal and Veterinary adverse event reports, export of 30 Oct 2026. Reports received through 26 Jun 2026.

Where the data come from

The counts come from the openFDA Animal and Veterinary adverse event files, export of 30 Oct 2026. The files have the reports that the FDA Center for Veterinary Medicine received through 26 Jun 2026. The files mask brand and manufacturer names. The site counts a drug by the active ingredients that each record gives, and gives no count to a brand, an application or a company. Ingredient names and the lists of approved products follow the FDA Green Book of 2 Nov 2026. The month is the month in which FDA received the report, not the month of the event.

The site does not publish report text, lot numbers or details of a reporter. FDA's record is the authority. See how the site counts reports, the data sources and the corrections page.

Questions about this month

Can the count for July 2021 change?: Yes. FDA says that a report can take 3 to 6 months to reach the public data. The newest months can get more reports in a later update.
Does the month show when the event occurred?: No. The month is the month in which FDA received the report. The event can be from an earlier month.
Which sign is in the largest number of the reports of the month?: "Vomiting" is in 992 reports of the 6,078 reports of July 2021 (16.3%).