July 2006: adverse event reports received

2,152 reports in the openFDA release of 28 Sep 2026

Read this first · FDA's caveat, in its words

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another. When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event. This dataset should not be the sole source of information for clinical decision-making or other assumptions about the safety or effectiveness of a product. The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources. FDA Center for Veterinary Medicine

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Not veterinary advice. This site lists what was reported to FDA. For an animal that is unwell, contact a veterinarian.

2,152reports received

1,671same month a year earlier+29%

1,684monthly average, preceding 12 months

70.2%concern dogscats 10%

FDA's database holds 2,152 adverse event reports received in July 2006, against 1,671 in the same month a year earlier and a monthly average of 1,684 over the preceding 12 months.

70.2% of the month's reports concern dogs, 10% cats and 2% horses; the rest concern other species, exposed people, or give no species.

By active ingredient, the drugs named most often were selamectin (306), ivermectin + pyrantel pamoate (280) and milbemycin oxime (256), and the terms listed most often were vomiting (319), ineffective, heartworm larvae (305) and depression (266). Report volume has a seasonal shape, with more reports in the warmer months when parasite products are in heavier use.

The months around it

Drugs named most often, by active ingredient

Active ingredients recorded for the drug	Reports	Share of the month's reports
Selamectin	306	14.2%
Ivermectin + Pyrantel Pamoate	280	13%
Milbemycin Oxime	256	11.9%
Carprofen	167	7.8%
Cyclosporine	112	5.2%
Lufenuron + Milbemycin Oxime	88	4.1%
Deracoxib	83	3.9%
Melarsomine Dihydrochloride	81	3.8%
Meloxicam	73	3.4%
Nitenpyram	51	2.4%
Firocoxib	48	2.2%
Amoxicillin	38	1.8%
Ivermectin	38	1.8%
Ivermectin + Praziquantel	24	1.1%
Monensin	19	0.9%

Ordered by report count, which follows how widely each drug was in use. FDA states that these data cannot be used to estimate risk or to compare one product with another. Brand and manufacturer names are masked by FDA in these records.

Signs listed most often

Vomiting14.8%319
Ineffective, heartworm larvae[legacy FDA term: the product did not have the expected effect (heartworm larvae)]14.2%305
Depression[dull, quiet or withdrawn]12.4%266
Anorexia[not eating]10.6%228
Diarrhoea[diarrhea]7.5%161
Death7.2%156
Accidental exposure[exposure that was not intended]5.1%109
Elevated alanine aminotransferase (ALT)[a liver enzyme above the normal range]4.6%98
Elevated serum alkaline phosphatase (SAP)[a liver and bone enzyme above the normal range]4.6%98
Lack of efficacy (endoparasite) - hookworm[the product did not have the expected effect: hookworms]4.1%88
Ataxia[unsteady, uncoordinated movement]3.6%78
Convulsion[seizure]3.4%73
Elevated blood urea nitrogen (BUN)[a kidney value above the normal range]3.2%69
Death by euthanasia[the animal was euthanized]3.1%67
Fever3%64

Single ingredients, pooled

Ivermectin16.3%350

Milbemycin Oxime16%344

Selamectin14.2%306

Pyrantel Pamoate14%302

Carprofen7.8%167

Cyclosporine5.2%112

Lufenuron4.6%100

Deracoxib3.9%83

Melarsomine Dihydrochloride3.8%81

Meloxicam3.4%73

Nitenpyram2.4%51

Firocoxib2.2%48

Species

Dog70.2%1,510

Cat10%216

Horse2%43

Other or not given17.8%383

Questions about July 2006

How many animal drug adverse event reports did FDA receive in July 2006?

2,152 reports are in the openFDA release of 28 Sep 2026. The same month a year earlier has 1,671.

Which drugs were named most often?

By active ingredient: selamectin (306), ivermectin + pyrantel pamoate (280), milbemycin oxime (256), carprofen (167) and cyclosporine (112). Brands are masked in the public data.

Which signs were listed most often?

vomiting (319), ineffective, heartworm larvae (305), depression (266), anorexia (228) and diarrhoea (161).

Can the count for a month still change?

Yes. FDA posts reports quarterly with a delay of three to six months, so the newest months are incomplete and usually grow in later releases. Older months change little.

Does a busy month mean something went wrong that month?

Not by itself. The date is when FDA received the report, not when the event happened, and volume follows season, product launches and publicity. FDA states that "there is no certainty that the reported drug or device caused the adverse event" and that the event "may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources."

Where this comes from. Counts are built from the openFDA Animal & Veterinary adverse event bulk files released 28 Sep 2026, which hold reports FDA's Center for Veterinary Medicine received through 31 Mar 2026. openFDA masks brand and manufacturer names in these files, so drugs are counted by the active ingredients each record discloses and no figure is attributed to a brand, application or company. Ingredient names, and the separate reference lists of approved products, follow the FDA Green Book as of 1 Oct 2026. The month is the date FDA first received the report, not the date of the event. No report text, lot numbers or reporter details are published. See the methodology and sources; FDA's record is authoritative, and corrections are handled within five working days.