July 2000: adverse event reports received

1,294 reports in the openFDA release of 28 Sep 2026

Read this first · FDA's caveat, in its words

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another. When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event. This dataset should not be the sole source of information for clinical decision-making or other assumptions about the safety or effectiveness of a product. The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources. FDA Center for Veterinary Medicine

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Not veterinary advice. This site lists what was reported to FDA. For an animal that is unwell, contact a veterinarian.

1,294reports received

1,449same month a year earlier-11%

1,435monthly average, preceding 12 months

61%concern dogscats 14.5%

FDA's database holds 1,294 adverse event reports received in July 2000, against 1,449 in the same month a year earlier and a monthly average of 1,435 over the preceding 12 months.

61% of the month's reports concern dogs, 14.5% cats and 2.3% horses; the rest concern other species, exposed people, or give no species.

By active ingredient, the drugs named most often were selamectin (501), carprofen (319) and selegiline hydrochloride (60), and the terms listed most often were accidental exposure (177), vomiting (168) and depression (150). Report volume has a seasonal shape, with more reports in the warmer months when parasite products are in heavier use.

The months around it

Drugs named most often, by active ingredient

Active ingredients recorded for the drug	Reports	Share of the month's reports
Selamectin	501	38.7%
Carprofen	319	24.7%
Selegiline Hydrochloride	60	4.6%
Florfenicol	39	3%
Milbemycin Oxime	31	2.4%
Enrofloxacin	26	2%
Lufenuron + Milbemycin Oxime	21	1.6%
(S) - methoprene	20	1.5%
Amoxicillin	18	1.4%
Oxibendazole	17	1.3%
Melarsomine Dihydrochloride	15	1.2%
Deslorelin Acetate	11	0.9%
Ivermectin	11	0.9%
Pyrantel Tartrate	11	0.9%
Tilmicosin Phosphate	11	0.9%

Ordered by report count, which follows how widely each drug was in use. FDA states that these data cannot be used to estimate risk or to compare one product with another. Brand and manufacturer names are masked by FDA in these records.

Signs listed most often

Accidental exposure[exposure that was not intended]13.7%177
Vomiting13%168
Depression[dull, quiet or withdrawn]11.6%150
Anorexia[not eating]9.4%121
No sign[no clinical sign was reported]9.2%119
Diarrhoea[diarrhea]7.2%93
Lack of efficacy (ectoparasite) - flea[the product did not have the expected effect: fleas]6.5%84
Elevated alanine aminotransferase (ALT)[a liver enzyme above the normal range]5.2%67
Death5%65
Elevated serum alkaline phosphatase (SAP)[a liver and bone enzyme above the normal range]5%65
Pruritus[itching]4.6%60
Unclassifiable adverse event[event that fits no dictionary term]4.5%58
Ataxia[unsteady, uncoordinated movement]3.6%46
Convulsion[seizure]3.1%40
Elevated total bilirubin[bilirubin above the normal range]2.8%36

Single ingredients, pooled

Selamectin38.7%501

Carprofen24.7%319

Selegiline Hydrochloride4.6%60

Milbemycin Oxime4%52

Florfenicol3%39

Enrofloxacin2%26

Lufenuron1.8%23

(S) - methoprene1.5%20

Amoxicillin1.4%18

Oxibendazole1.3%17

Ivermectin1.2%15

Melarsomine Dihydrochloride1.2%15

Species

Dog61%789

Cat14.5%187

Horse2.3%30

Other or not given22.3%288

Questions about July 2000

How many animal drug adverse event reports did FDA receive in July 2000?

1,294 reports are in the openFDA release of 28 Sep 2026. The same month a year earlier has 1,449.

Which drugs were named most often?

By active ingredient: selamectin (501), carprofen (319), selegiline hydrochloride (60), florfenicol (39) and milbemycin oxime (31). Brands are masked in the public data.

Which signs were listed most often?

accidental exposure (177), vomiting (168), depression (150), anorexia (121) and no sign (119).

Can the count for a month still change?

Yes. FDA posts reports quarterly with a delay of three to six months, so the newest months are incomplete and usually grow in later releases. Older months change little.

Does a busy month mean something went wrong that month?

Not by itself. The date is when FDA received the report, not when the event happened, and volume follows season, product launches and publicity. FDA states that "there is no certainty that the reported drug or device caused the adverse event" and that the event "may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources."

Where this comes from. Counts are built from the openFDA Animal & Veterinary adverse event bulk files released 28 Sep 2026, which hold reports FDA's Center for Veterinary Medicine received through 31 Mar 2026. openFDA masks brand and manufacturer names in these files, so drugs are counted by the active ingredients each record discloses and no figure is attributed to a brand, application or company. Ingredient names, and the separate reference lists of approved products, follow the FDA Green Book as of 1 Oct 2026. The month is the date FDA first received the report, not the date of the event. No report text, lot numbers or reporter details are published. See the methodology and sources; FDA's record is authoritative, and corrections are handled within five working days.