July 1999: adverse event reports received

1,449 reports in the openFDA release of 28 Sep 2026

Read this first · FDA's caveat, in its words

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another. When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event. This dataset should not be the sole source of information for clinical decision-making or other assumptions about the safety or effectiveness of a product. The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources. FDA Center for Veterinary Medicine

Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.

Not veterinary advice. This site lists what was reported to FDA. For an animal that is unwell, contact a veterinarian.

1,449reports received

530same month a year earlier+173%

895monthly average, preceding 12 months

74.6%concern dogscats 5.5%

FDA's database holds 1,449 adverse event reports received in July 1999, against 530 in the same month a year earlier and a monthly average of 895 over the preceding 12 months.

74.6% of the month's reports concern dogs, 5.5% cats and 4% horses; the rest concern other species, exposed people, or give no species.

By active ingredient, the drugs named most often were selegiline hydrochloride (539), carprofen (137) and betamethasone valerate + clotrimazole + gentamicin sulfate (75), and the terms listed most often were vomiting (144), depression (132) and lack of efficacy - NOS (106). Report volume has a seasonal shape, with more reports in the warmer months when parasite products are in heavier use.

The months around it

Drugs named most often, by active ingredient

Active ingredients recorded for the drug	Reports	Share of the month's reports
Selegiline Hydrochloride	539	37.2%
Carprofen	137	9.5%
Betamethasone Valerate + Clotrimazole + Gentamicin Sulfate	75	5.2%
Etodolac	71	4.9%
Oxibendazole	68	4.7%
Moxidectin	61	4.2%
Milbemycin Oxime	42	2.9%
Lufenuron + Milbemycin Oxime	40	2.8%
Melarsomine Dihydrochloride	38	2.6%
Amoxicillin	32	2.2%
Ketamine Hydrochloride	32	2.2%
Ivermectin	21	1.4%
Pyrantel Pamoate	18	1.2%
Lufenuron	17	1.2%
Tilmicosin Phosphate	17	1.2%

Ordered by report count, which follows how widely each drug was in use. FDA states that these data cannot be used to estimate risk or to compare one product with another. Brand and manufacturer names are masked by FDA in these records.

Signs listed most often

Vomiting9.9%144
Depression[dull, quiet or withdrawn]9.1%132
Lack of efficacy - NOS[the product did not have the expected effect]7.3%106
Anorexia[not eating]7.2%104
Diarrhoea[diarrhea]6.4%93
Accidental exposure[exposure that was not intended]5.8%84
Death5.7%83
Ineffective, loss of effect[legacy FDA term: the product did not have the expected effect (loss of effect)]5.3%77
No sign[no clinical sign was reported]5%72
Deafness4.6%66
Ineffective, heartworm larvae[legacy FDA term: the product did not have the expected effect (heartworm larvae)]4.1%59
Ataxia[unsteady, uncoordinated movement]4%58
Polydipsia[drinking more than usual]3.9%56
Polypnoea[fast breathing]3.8%55
Convulsion[seizure]3.7%53

Single ingredients, pooled

Selegiline Hydrochloride37.2%539

Carprofen9.5%137

Milbemycin Oxime5.7%82

Gentamicin Sulfate5.2%76

Betamethasone Valerate5.2%75

Clotrimazole5.2%75

Etodolac4.9%71

Oxibendazole4.7%68

Moxidectin4.2%61

Lufenuron3.9%57

Melarsomine Dihydrochloride2.6%38

Amoxicillin2.2%32

Species

Dog74.6%1,081

Cat5.5%79

Horse4%58

Other or not given15.9%231

Questions about July 1999

How many animal drug adverse event reports did FDA receive in July 1999?

1,449 reports are in the openFDA release of 28 Sep 2026. The same month a year earlier has 530.

Which drugs were named most often?

By active ingredient: selegiline hydrochloride (539), carprofen (137), betamethasone valerate + clotrimazole + gentamicin sulfate (75), etodolac (71) and oxibendazole (68). Brands are masked in the public data.

Which signs were listed most often?

vomiting (144), depression (132), lack of efficacy - NOS (106), anorexia (104) and diarrhoea (93).

Can the count for a month still change?

Yes. FDA posts reports quarterly with a delay of three to six months, so the newest months are incomplete and usually grow in later releases. Older months change little.

Does a busy month mean something went wrong that month?

Not by itself. The date is when FDA received the report, not when the event happened, and volume follows season, product launches and publicity. FDA states that "there is no certainty that the reported drug or device caused the adverse event" and that the event "may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources."

Where this comes from. Counts are built from the openFDA Animal & Veterinary adverse event bulk files released 28 Sep 2026, which hold reports FDA's Center for Veterinary Medicine received through 31 Mar 2026. openFDA masks brand and manufacturer names in these files, so drugs are counted by the active ingredients each record discloses and no figure is attributed to a brand, application or company. Ingredient names, and the separate reference lists of approved products, follow the FDA Green Book as of 1 Oct 2026. The month is the date FDA first received the report, not the date of the event. No report text, lot numbers or reporter details are published. See the methodology and sources; FDA's record is authoritative, and corrections are handled within five working days.