November 2016: adverse event reports that FDA received

Month in which FDA received the reports

Read this first. FDA says this about the data:

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another. When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event. This dataset should not be the sole source of information for clinical decision-making or other assumptions about the safety or effectiveness of a product. The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources.
FDA Center for Veterinary Medicine publishes these words. Source: Adverse Event Reports for Animal Drugs and Devices, read on 2 Oct 2026. The data have the reports that FDA received through 26 Jun 2026.

FDA received 5,415 adverse event reports for animal drugs in November 2016. It received 5,176 reports in November 2015. The average of the 12 months before November 2016 is 6,165 reports for each month.

Of the 5,415 reports, 73.1% are about dogs, 11.7% are about cats and 1% are about horses. The other reports are about other species, or give no species. A report is not proof that a drug caused a sign.

Search engines do not list month pages. The site keeps the page, and the list of months links it.

The months before and after

Reports for each month, May 2015 to May 2017. The column with the outline is November 2016.

Reports by species

Dog73.1%3,961
Cat11.7%636
Horse1%55
Other species, or species not given14.1%763

Drug pages with reports received in November 2016

The table has every drug page with 10 or more reports that FDA received in November 2016, in order of name. No count decides which drug is in the table. The table has 76 drug pages.

Show the 76 drug pages

Drug pages with 10 or more reports received in November 2016, in order of name
Active ingredients	Reports received in November 2016
(S) - methoprene	24
Afoxolaner	533
Amoxicillin	14
Amoxicillin + Clavulanate Potassium	24
Atipamezole Hydrochloride	15
Betamethasone Valerate + Clotrimazole + Gentamicin Sulfate	13
Buprenorphine	19
Butorphanol Tartrate	27
Carprofen	102
Cefovecin sodium	45
Cefpodoxime proxetil	37
Ceftiofur Crystalline Free Acid	11
Cephalexin	20
Clindamycin	11
Cyclosporine	49
Deracoxib	18
Desoxycorticosterone Pivalate	11
Dexamethasone	13
Dexmedetomidine	10
Dexmedetomidine hydrochloride	29
Diphenhydramine	26
Doxycycline	11
Emodepside + Praziquantel	41
Enrofloxacin	28
Famotidine	17
Febantel + Praziquantel + Pyrantel Pamoate	34
Firocoxib	35
Florfenicol + Mometasone furoate + Terbinafine	25
Florfenicol + Terbinafine	38
Fluralaner	545
Gabapentin	12
Hyaluronate Sodium	11
Hydromorphone	12
Imidacloprid	23
Imidacloprid + Moxidectin	92
Insulin	60
Isoflurane	20
Ivermectin	55
Ivermectin + Praziquantel	27
Ivermectin + Praziquantel + Pyrantel Pamoate	13
Ivermectin + Pyrantel Pamoate	785
Ketamine Hydrochloride	23
Ketoconazole	19
Levothyroxine sodium	13
Lufenuron	17
Lufenuron + Milbemycin Oxime	140
Lufenuron + Praziquantel	66
Maropitant	66
Melarsomine Dihydrochloride	76
Meloxicam	48
Methylprednisolone Acetate	13
Metronidazole	20
Milbemycin Oxime	92
Milbemycin Oxime + Praziquantel	141
Milbemycin Oxime + Spinosad	754
Monensin	21
Moxidectin	147
Nitenpyram	258
Oclacitinib	306
Orbifloxacin	10
Phenobarbital	10
Pimobendan	16
Polysulfated Glycosaminoglycan	30
Praziquantel	16
Praziquantel + Pyrantel Pamoate	11
Prednisolone	16
Prednisone	51
Propofol	13
Pyrantel Pamoate	14
Robenacoxib	22
Sarolaner	51
Selamectin	202
Spinosad	323
Tramadol	20
Trilostane	65
Tulathromycin	19

The openFDA records give the value "MSK" for the brand name and for the manufacturer name of each drug. FDA says that MSK means "masked". So the site cannot count a report for a brand.

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another.
Commonly used products may have a higher number of reported adverse events due to the higher total number of animals being given the product.
FDA Center for Veterinary Medicine. Source: Adverse Event Reports for Animal Drugs and Devices

Signs that the reports of the month list

A sign is a coded term from the report. The words in brackets are a plain gloss of the term. The percentage is the share of the 5,415 reports of the month.

The sign that is in the largest number of the reports comes first.

Vomiting21.3%1,155 reports
Lethargy[unusually tired or inactive]9.3%503 reports
Ineffective, heartworm larvae[legacy FDA term: the product did not have the expected effect (heartworm larvae)]7.1%382 reports
Lack of efficacy (ectoparasite) - flea[the product did not have the expected effect: fleas]6.8%367 reports
Diarrhoea[diarrhea]6%325 reports
Digestive tract disorder NOS[digestive problem, type not specified]5.3%286 reports
Lack of efficacy (endoparasite) - hookworm[the product did not have the expected effect: hookworms]4.9%267 reports
Product problem[a product quality report, not a sign in an animal]4.1%223 reports
Unpalatable[legacy FDA term: the animal would not take it]3.4%183 reports
Ineffective, ascarids NOS[legacy FDA term: the product did not have the expected effect (ascarids nos)]3.1%169 reports
Anorexia[not eating]2.9%159 reports
Lack of efficacy - NOS[the product did not have the expected effect]2.9%159 reports
Seizure NOS[seizure, type not specified]2.6%141 reports
Death2.6%140 reports

Show the next 1 signs

Other abnormal test result NOS[abnormal laboratory result, type not specified]2.5%137 reports

Ingredients, all combinations

The list has every active ingredient with 10 or more reports received in November 2016, in order of name. It has 72 ingredients.

Show the 72 ingredients

The same month in other years

Cite this page

Pet Drug Reports. November 2016: adverse event reports for animal drugs. https://petdrugreports.com/month/2016-11/ Source: FDA Center for Veterinary Medicine, openFDA Animal and Veterinary adverse event reports, export of 30 Oct 2026. Reports received through 26 Jun 2026.

Where the data come from

The counts come from the openFDA Animal and Veterinary adverse event files, export of 30 Oct 2026. The files have the reports that the FDA Center for Veterinary Medicine received through 26 Jun 2026. The files mask brand and manufacturer names. The site counts a drug by the active ingredients that each record gives, and gives no count to a brand, an application or a company. Ingredient names and the lists of approved products follow the FDA Green Book of 2 Nov 2026. The month is the month in which FDA received the report, not the month of the event.

The site does not publish report text, lot numbers or details of a reporter. FDA's record is the authority. See how the site counts reports, the data sources and the corrections page.

Questions about this month

Can the count for November 2016 change?: Yes. FDA says that a report can take 3 to 6 months to reach the public data. The newest months can get more reports in a later update.
Does the month show when the event occurred?: No. The month is the month in which FDA received the report. The event can be from an earlier month.
Which sign is in the largest number of the reports of the month?: "Vomiting" is in 1,155 reports of the 5,415 reports of November 2016 (21.3%).