November 1997: adverse event reports received

944 reports in the openFDA release of 28 Sep 2026

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An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another. When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event. This dataset should not be the sole source of information for clinical decision-making or other assumptions about the safety or effectiveness of a product. The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources. FDA Center for Veterinary Medicine

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944reports received

189same month a year earlier+399%

349monthly average, preceding 12 months

78.2%concern dogscats 4.1%

FDA's database holds 944 adverse event reports received in November 1997, against 189 in the same month a year earlier and a monthly average of 349 over the preceding 12 months.

78.2% of the month's reports concern dogs, 4.1% cats and 5.3% horses; the rest concern other species, exposed people, or give no species.

By active ingredient, the drugs named most often were carprofen (642), moxidectin (52) and dinoprost tromethamine (33), and the terms listed most often were anorexia (165), vomiting (163) and elevated serum alkaline phosphatase (SAP) (148). Report volume has a seasonal shape, with more reports in the warmer months when parasite products are in heavier use.

The months around it

Drugs named most often, by active ingredient

Active ingredients recorded for the drug	Reports	Share of the month's reports
Carprofen	642	68%
Moxidectin	52	5.5%
Dinoprost Tromethamine	33	3.5%
Amoxicillin	20	2.1%
Atipamezole Hydrochloride	18	1.9%
Melarsomine Dihydrochloride	16	1.7%
Ivermectin	11	1.2%
Ketamine Hydrochloride	10	1.1%
Tiletamine Hydrochloride + Zolazepam Hydrochloride	9	1%
Tilmicosin Phosphate	9	1%
Enrofloxacin	7	0.7%
Lufenuron	7	0.7%
Orbifloxacin	7	0.7%
Febantel + Praziquantel + Pyrantel Pamoate	5	0.5%
Fenbendazole	5	0.5%

Ordered by report count, which follows how widely each drug was in use. FDA states that these data cannot be used to estimate risk or to compare one product with another. Brand and manufacturer names are masked by FDA in these records.

Signs listed most often

Anorexia[not eating]17.5%165
Vomiting17.3%163
Elevated serum alkaline phosphatase (SAP)[a liver and bone enzyme above the normal range]15.7%148
Elevated alanine aminotransferase (ALT)[a liver enzyme above the normal range]14.9%141
Depression[dull, quiet or withdrawn]12%113
Diarrhoea[diarrhea]10.6%100
Elevated total bilirubin[bilirubin above the normal range]5.7%54
Death5.5%52
Elevated liver enzymes[liver enzymes above the normal range]5.2%49
Icterus[jaundice (yellowing)]4.9%46
PR-liver, lesion(s)[legacy FDA term: lesions found in the liver]4.2%40
Elevated blood urea nitrogen (BUN)[a kidney value above the normal range]4.1%39
Anaemia NOS[low red blood cell count]4%38
Ineffective, analgesia[legacy FDA term: the product did not have the expected effect (analgesia)]3.9%37
Thrombocytopenia[low platelet count]3.7%35

Single ingredients, pooled

Carprofen68%642

Moxidectin5.5%52

Dinoprost Tromethamine3.5%33

Amoxicillin2.1%20

Atipamezole Hydrochloride1.9%18

Melarsomine Dihydrochloride1.7%16

Ivermectin1.4%13

Ketamine Hydrochloride1.1%10

Pyrantel Pamoate1.1%10

Tiletamine Hydrochloride1%9

Tilmicosin Phosphate1%9

Zolazepam Hydrochloride1%9

Species

Dog78.2%738

Cat4.1%39

Horse5.3%50

Other or not given12.4%117

Questions about November 1997

How many animal drug adverse event reports did FDA receive in November 1997?

944 reports are in the openFDA release of 28 Sep 2026. The same month a year earlier has 189.

Which drugs were named most often?

By active ingredient: carprofen (642), moxidectin (52), dinoprost tromethamine (33), amoxicillin (20) and atipamezole hydrochloride (18). Brands are masked in the public data.

Which signs were listed most often?

anorexia (165), vomiting (163), elevated serum alkaline phosphatase (SAP) (148), elevated alanine aminotransferase (ALT) (141) and depression (113).

Can the count for a month still change?

Yes. FDA posts reports quarterly with a delay of three to six months, so the newest months are incomplete and usually grow in later releases. Older months change little.

Does a busy month mean something went wrong that month?

Not by itself. The date is when FDA received the report, not when the event happened, and volume follows season, product launches and publicity. FDA states that "there is no certainty that the reported drug or device caused the adverse event" and that the event "may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources."

Where this comes from. Counts are built from the openFDA Animal & Veterinary adverse event bulk files released 28 Sep 2026, which hold reports FDA's Center for Veterinary Medicine received through 31 Mar 2026. openFDA masks brand and manufacturer names in these files, so drugs are counted by the active ingredients each record discloses and no figure is attributed to a brand, application or company. Ingredient names, and the separate reference lists of approved products, follow the FDA Green Book as of 1 Oct 2026. The month is the date FDA first received the report, not the date of the event. No report text, lot numbers or reporter details are published. See the methodology and sources; FDA's record is authoritative, and corrections are handled within five working days.