November 2010: adverse event reports received

3,373 reports in the openFDA release of 28 Sep 2026

Read this first · FDA's caveat, in its words

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another. When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event. This dataset should not be the sole source of information for clinical decision-making or other assumptions about the safety or effectiveness of a product. The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources. FDA Center for Veterinary Medicine

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Not veterinary advice. This site lists what was reported to FDA. For an animal that is unwell, contact a veterinarian.

3,373reports received

3,131same month a year earlier+8%

3,528monthly average, preceding 12 months

73.2%concern dogscats 10.2%

FDA's database holds 3,373 adverse event reports received in November 2010, against 3,131 in the same month a year earlier and a monthly average of 3,528 over the preceding 12 months.

73.2% of the month's reports concern dogs, 10.2% cats and 1.5% horses; the rest concern other species, exposed people, or give no species.

By active ingredient, the drugs named most often were spinosad (817), ivermectin + pyrantel pamoate (511) and milbemycin oxime (226), and the terms listed most often were vomiting (791), ineffective, heartworm larvae (424) and depression (366). Report volume has a seasonal shape, with more reports in the warmer months when parasite products are in heavier use.

The months around it

Drugs named most often, by active ingredient

Active ingredients recorded for the drug	Reports	Share of the month's reports
Spinosad	817	24.2%
Ivermectin + Pyrantel Pamoate	511	15.1%
Milbemycin Oxime	226	6.7%
Selamectin	182	5.4%
Imidacloprid + Moxidectin	111	3.3%
Amoxicillin	97	2.9%
Carprofen	91	2.7%
Meloxicam	89	2.6%
Cyclosporine	81	2.4%
Lufenuron + Milbemycin Oxime	78	2.3%
Melarsomine Dihydrochloride	76	2.3%
Cefovecin sodium	61	1.8%
Firocoxib	52	1.5%
Deracoxib	45	1.3%
Ivermectin + Praziquantel + Pyrantel Pamoate	43	1.3%

Ordered by report count, which follows how widely each drug was in use. FDA states that these data cannot be used to estimate risk or to compare one product with another. Brand and manufacturer names are masked by FDA in these records.

Signs listed most often

Vomiting23.5%791
Ineffective, heartworm larvae[legacy FDA term: the product did not have the expected effect (heartworm larvae)]12.6%424
Depression[dull, quiet or withdrawn]10.9%366
Anorexia[not eating]7.6%257
Diarrhoea[diarrhea]5.7%191
Lack of efficacy (ectoparasite) - flea[the product did not have the expected effect: fleas]4.5%151
Ineffective, ascarids NOS[legacy FDA term: the product did not have the expected effect (ascarids nos)]4.3%144
Accidental exposure[exposure that was not intended]4%135
Death3.9%131
Lack of efficacy (endoparasite) - hookworm[the product did not have the expected effect: hookworms]3.6%122
Ataxia[unsteady, uncoordinated movement]3.5%118
Convulsion[seizure]3.1%106
Pruritus[itching]2.6%87
Elevated alanine aminotransferase (ALT)[a liver enzyme above the normal range]2.5%86
Color, Abnormal[a product quality report, not a sign in an animal]2.5%85

Single ingredients, pooled

Spinosad24.3%818

Pyrantel Pamoate18.5%624

Ivermectin18.4%619

Milbemycin Oxime9.1%306

Selamectin5.4%182

Moxidectin4.4%149

Praziquantel4%136

Imidacloprid3.3%111

Amoxicillin2.9%97

Carprofen2.7%91

Meloxicam2.6%89

Lufenuron2.5%85

Species

Dog73.2%2,468

Cat10.2%344

Horse1.5%51

Other or not given15.1%510

Questions about November 2010

How many animal drug adverse event reports did FDA receive in November 2010?

3,373 reports are in the openFDA release of 28 Sep 2026. The same month a year earlier has 3,131.

Which drugs were named most often?

By active ingredient: spinosad (817), ivermectin + pyrantel pamoate (511), milbemycin oxime (226), selamectin (182) and imidacloprid + moxidectin (111). Brands are masked in the public data.

Which signs were listed most often?

vomiting (791), ineffective, heartworm larvae (424), depression (366), anorexia (257) and diarrhoea (191).

Can the count for a month still change?

Yes. FDA posts reports quarterly with a delay of three to six months, so the newest months are incomplete and usually grow in later releases. Older months change little.

Does a busy month mean something went wrong that month?

Not by itself. The date is when FDA received the report, not when the event happened, and volume follows season, product launches and publicity. FDA states that "there is no certainty that the reported drug or device caused the adverse event" and that the event "may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources."

Where this comes from. Counts are built from the openFDA Animal & Veterinary adverse event bulk files released 28 Sep 2026, which hold reports FDA's Center for Veterinary Medicine received through 31 Mar 2026. openFDA masks brand and manufacturer names in these files, so drugs are counted by the active ingredients each record discloses and no figure is attributed to a brand, application or company. Ingredient names, and the separate reference lists of approved products, follow the FDA Green Book as of 1 Oct 2026. The month is the date FDA first received the report, not the date of the event. No report text, lot numbers or reporter details are published. See the methodology and sources; FDA's record is authoritative, and corrections are handled within five working days.