September 2016: adverse event reports that FDA received

Month in which FDA received the reports

Read this first. FDA says this about the data:

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another. When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event. This dataset should not be the sole source of information for clinical decision-making or other assumptions about the safety or effectiveness of a product. The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources.
FDA Center for Veterinary Medicine publishes these words. Source: Adverse Event Reports for Animal Drugs and Devices, read on 2 Oct 2026. The data have the reports that FDA received through 26 Jun 2026.

FDA received 6,534 adverse event reports for animal drugs in September 2016. It received 6,402 reports in September 2015. The average of the 12 months before September 2016 is 6,192 reports for each month.

Of the 6,534 reports, 74% are about dogs, 8.7% are about cats and 0.9% are about horses. The other reports are about other species, or give no species. A report is not proof that a drug caused a sign.

Search engines do not list month pages. The site keeps the page, and the list of months links it.

The months before and after

Reports for each month, Mar 2015 to Mar 2017. The column with the outline is September 2016.

Reports by species

Dog74%4,833
Cat8.7%570
Horse0.9%59
Other species, or species not given16.4%1,072

Drug pages with reports received in September 2016

The table has every drug page with 10 or more reports that FDA received in September 2016, in order of name. No count decides which drug is in the table. The table has 75 drug pages.

Show the 75 drug pages

Drug pages with 10 or more reports received in September 2016, in order of name
Active ingredients	Reports received in September 2016
(S) - methoprene	24
Afoxolaner	647
Amoxicillin	17
Amoxicillin + Clavulanate Potassium	26
Amoxicillin Trihydrate + Clavulanate Potassium	14
Atipamezole Hydrochloride	11
Buprenorphine	16
Butorphanol Tartrate	22
Carprofen	121
Cefovecin sodium	73
Cefpodoxime proxetil	23
Cephalexin	33
Cyclosporine	84
Deracoxib	25
Dexamethasone	13
Dexmedetomidine hydrochloride	39
Dinoprost Tromethamine	10
Diphenhydramine	30
Doxycycline	10
Emodepside + Praziquantel	31
Enalapril Maleate	10
Enrofloxacin	36
Eprinomectin	13
Estradiol Benzoate + Trenbolone Acetate	20
Estriol	13
Famotidine	26
Febantel + Praziquantel + Pyrantel Pamoate	49
Fenbendazole	16
Firocoxib	25
Florfenicol + Mometasone furoate + Terbinafine	272
Florfenicol + Terbinafine	59
Fluralaner	642
Furosemide	15
Gabapentin	12
Hydroxyzine	10
Imidacloprid	20
Imidacloprid + Moxidectin	119
Insulin	102
Isoflurane	13
Ivermectin	76
Ivermectin + Praziquantel	22
Ivermectin + Pyrantel Pamoate	836
Ketamine Hydrochloride	13
Ketoconazole	16
Levothyroxine sodium	18
Lufenuron + Milbemycin Oxime	207
Lufenuron + Praziquantel	73
Maropitant	56
Melarsomine Dihydrochloride	93
Meloxicam	53
Methylprednisolone Acetate	13
Metronidazole	21
Milbemycin Oxime	78
Milbemycin Oxime + Praziquantel	141
Milbemycin Oxime + Spinosad	938
Mirtazapine	12
Monensin	17
Moxidectin	138
Nitenpyram	273
Oclacitinib	396
Pegbovigrastim	10
Pimobendan	19
Polysulfated Glycosaminoglycan	60
Praziquantel + Pyrantel Pamoate	10
Prednisolone	22
Prednisolone + Trimeprazine Tartrate	18
Prednisone	44
Pyrantel Pamoate	18
Robenacoxib	15
Sarolaner	64
Selamectin	242
Spinosad	459
Sucralfate	11
Tramadol	25
Trilostane	54

The openFDA records give the value "MSK" for the brand name and for the manufacturer name of each drug. FDA says that MSK means "masked". So the site cannot count a report for a brand.

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another.
Commonly used products may have a higher number of reported adverse events due to the higher total number of animals being given the product.
FDA Center for Veterinary Medicine. Source: Adverse Event Reports for Animal Drugs and Devices

Signs that the reports of the month list

A sign is a coded term from the report. The words in brackets are a plain gloss of the term. The percentage is the share of the 6,534 reports of the month.

The sign that is in the largest number of the reports comes first.

Vomiting21.9%1,434 reports
Lethargy[unusually tired or inactive]9%591 reports
Lack of efficacy (ectoparasite) - flea[the product did not have the expected effect: fleas]6.3%410 reports
Ineffective, heartworm larvae[legacy FDA term: the product did not have the expected effect (heartworm larvae)]6%393 reports
Diarrhoea[diarrhea]5.7%372 reports
Lack of efficacy (endoparasite) - hookworm[the product did not have the expected effect: hookworms]5.4%352 reports
Digestive tract disorder NOS[digestive problem, type not specified]4.5%296 reports
Tubes, Leaking[a product quality report, not a sign in an animal]3.9%253 reports
Unpalatable[legacy FDA term: the animal would not take it]3.2%212 reports
Product problem[a product quality report, not a sign in an animal]3%194 reports
Seizure NOS[seizure, type not specified]2.9%192 reports
Lack of efficacy (ectoparasite) - NOS[the product did not have the expected effect: target not specified]2.9%189 reports
Lack of efficacy - NOS[the product did not have the expected effect]2.8%184 reports
Anorexia[not eating]2.8%182 reports

Show the next 1 signs

Other abnormal test result NOS[abnormal laboratory result, type not specified]2.7%177 reports

Ingredients, all combinations

The list has every active ingredient with 10 or more reports received in September 2016, in order of name. It has 76 ingredients.

Show the 76 ingredients

The same month in other years

Cite this page

Pet Drug Reports. September 2016: adverse event reports for animal drugs. https://petdrugreports.com/month/2016-09/ Source: FDA Center for Veterinary Medicine, openFDA Animal and Veterinary adverse event reports, export of 30 Oct 2026. Reports received through 26 Jun 2026.

Where the data come from

The counts come from the openFDA Animal and Veterinary adverse event files, export of 30 Oct 2026. The files have the reports that the FDA Center for Veterinary Medicine received through 26 Jun 2026. The files mask brand and manufacturer names. The site counts a drug by the active ingredients that each record gives, and gives no count to a brand, an application or a company. Ingredient names and the lists of approved products follow the FDA Green Book of 2 Nov 2026. The month is the month in which FDA received the report, not the month of the event.

The site does not publish report text, lot numbers or details of a reporter. FDA's record is the authority. See how the site counts reports, the data sources and the corrections page.

Questions about this month

Can the count for September 2016 change?: Yes. FDA says that a report can take 3 to 6 months to reach the public data. The newest months can get more reports in a later update.
Does the month show when the event occurred?: No. The month is the month in which FDA received the report. The event can be from an earlier month.
Which sign is in the largest number of the reports of the month?: "Vomiting" is in 1,434 reports of the 6,534 reports of September 2016 (21.9%).