September 2000: adverse event reports received

1,640 reports in the openFDA release of 28 Sep 2026

Read this first · FDA's caveat, in its words

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another. When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event. This dataset should not be the sole source of information for clinical decision-making or other assumptions about the safety or effectiveness of a product. The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources. FDA Center for Veterinary Medicine

Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.

Not veterinary advice. This site lists what was reported to FDA. For an animal that is unwell, contact a veterinarian.

1,640reports received

817same month a year earlier+101%

1,503monthly average, preceding 12 months

44.9%concern dogscats 11.8%

FDA's database holds 1,640 adverse event reports received in September 2000, against 817 in the same month a year earlier and a monthly average of 1,503 over the preceding 12 months.

44.9% of the month's reports concern dogs, 11.8% cats and 3.5% horses; the rest concern other species, exposed people, or give no species.

By active ingredient, the drugs named most often were selamectin (352), carprofen (345) and doramectin (295), and the terms listed most often were accidental exposure (210), pruritus (164) and lack of efficacy (ectoparasite) - lice (160). Report volume has a seasonal shape, with more reports in the warmer months when parasite products are in heavier use.

The months around it

Drugs named most often, by active ingredient

Active ingredients recorded for the drug	Reports	Share of the month's reports
Selamectin	352	21.5%
Carprofen	345	21%
Doramectin	295	18%
Moxidectin	144	8.8%
Selegiline Hydrochloride	57	3.5%
Etodolac	34	2.1%
Milbemycin Oxime	31	1.9%
Amoxicillin	25	1.5%
Lufenuron + Milbemycin Oxime	22	1.3%
Oxibendazole	19	1.2%
Ketamine Hydrochloride	18	1.1%
(S) - methoprene	18	1.1%
Clomipramine Hydrochloride	16	1%
Enrofloxacin	16	1%
Melarsomine Dihydrochloride	16	1%

Ordered by report count, which follows how widely each drug was in use. FDA states that these data cannot be used to estimate risk or to compare one product with another. Brand and manufacturer names are masked by FDA in these records.

Signs listed most often

Accidental exposure[exposure that was not intended]12.8%210
Pruritus[itching]10%164
Lack of efficacy (ectoparasite) - lice[the product did not have the expected effect: lice]9.8%160
Vomiting9.3%153
No sign[no clinical sign was reported]8.6%141
Depression[dull, quiet or withdrawn]8.5%139
Alopecia NOS[hair loss, type not specified]6.8%112
Anorexia[not eating]6.5%107
Dispenser, Abnormal[a product quality report, not a sign in an animal]5.9%96
Elevated serum alkaline phosphatase (SAP)[a liver and bone enzyme above the normal range]4.7%77
Death4.6%76
Diarrhoea[diarrhea]4.4%72
Ataxia[unsteady, uncoordinated movement]4.2%69
Elevated alanine aminotransferase (ALT)[a liver enzyme above the normal range]3.8%63
Lack of efficacy (ectoparasite) - flea[the product did not have the expected effect: fleas]3.3%54

Single ingredients, pooled

Selamectin21.5%352

Carprofen21%345

Doramectin18%295

Moxidectin8.8%144

Selegiline Hydrochloride3.5%57

Milbemycin Oxime3.2%53

Etodolac2.1%34

Lufenuron1.6%27

Amoxicillin1.5%25

Pyrantel Pamoate1.3%21

Oxibendazole1.2%19

Ivermectin1.1%18

Species

Dog44.9%736

Cat11.8%193

Horse3.5%57

Other or not given39.9%654

Questions about September 2000

How many animal drug adverse event reports did FDA receive in September 2000?

1,640 reports are in the openFDA release of 28 Sep 2026. The same month a year earlier has 817.

Which drugs were named most often?

By active ingredient: selamectin (352), carprofen (345), doramectin (295), moxidectin (144) and selegiline hydrochloride (57). Brands are masked in the public data.

Which signs were listed most often?

accidental exposure (210), pruritus (164), lack of efficacy (ectoparasite) - lice (160), vomiting (153) and no sign (141).

Can the count for a month still change?

Yes. FDA posts reports quarterly with a delay of three to six months, so the newest months are incomplete and usually grow in later releases. Older months change little.

Does a busy month mean something went wrong that month?

Not by itself. The date is when FDA received the report, not when the event happened, and volume follows season, product launches and publicity. FDA states that "there is no certainty that the reported drug or device caused the adverse event" and that the event "may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources."

Where this comes from. Counts are built from the openFDA Animal & Veterinary adverse event bulk files released 28 Sep 2026, which hold reports FDA's Center for Veterinary Medicine received through 31 Mar 2026. openFDA masks brand and manufacturer names in these files, so drugs are counted by the active ingredients each record discloses and no figure is attributed to a brand, application or company. Ingredient names, and the separate reference lists of approved products, follow the FDA Green Book as of 1 Oct 2026. The month is the date FDA first received the report, not the date of the event. No report text, lot numbers or reporter details are published. See the methodology and sources; FDA's record is authoritative, and corrections are handled within five working days.