Hypoalbuminaemia: in adverse event reports for animal drugs

Clinical sign, a VeDDRA term

In plain words: low blood albumin.

Read this first. FDA says this about the data:

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another. When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event. This dataset should not be the sole source of information for clinical decision-making or other assumptions about the safety or effectiveness of a product. The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources.
FDA Center for Veterinary Medicine publishes these words. Source: Adverse Event Reports for Animal Drugs and Devices, read on 2 Oct 2026. The data have the reports that FDA received through 26 Jun 2026.

This page is not veterinary advice. For an animal that is ill, speak to a veterinarian.

Contacting a veterinarian How to report to FDA

From February 1987 to June 2026, FDA received 6,141 adverse event reports for animal drugs that list this sign. That is 0.5% of the 1,378,761 reports that FDA received from January 1987 to June 2026. In the 12 months to June 2026, FDA received 303 reports that list this sign.

Of the 6,141 reports, 91.1% are about dogs. A report can list more than one sign and more than one drug. A report is not proof that a drug caused a sign.

By number of reports in all years, this sign is number 102 of 1,149 clinical signs with a page. Reports that list this sign rose by 17.9% in the 12 months to June 2026, compared with the 12 months before. Reports for all animal drugs fell by 4.6% in the same periods. The newest months can get more reports in a later update. Reports about dogs are 91.1% of the reports that list this sign, and 72.6% of all reports.

Drug pages with reports that list this sign

The table has every drug page with 20 or more reports that list this sign, in order of name. No count decides which drug is in the table. The table has 90 drug pages.

Show the 90 drug pages

Drug pages with 20 or more reports that list this sign, in order of name
Active ingredients	Reports that list the sign
Acepromazine Maleate	37
Afoxolaner	182
Amoxicillin	128
Amoxicillin + Clavulanate Potassium	46
Amoxicillin Trihydrate + Clavulanate Potassium	55
Ampicillin Sodium	35
Atipamezole Hydrochloride	37
Atropine	26
Bedinvetmab	154
Buprenorphine	131
Butorphanol Tartrate	85
Capromorelin	54
Carprofen	1,460
Cefovecin sodium	192
Cefpodoxime proxetil	85
Cephalexin	42
Clindamycin	35
Cyclosporine	228
Deracoxib	686
Desoxycorticosterone Pivalate	56
Dexamethasone	89
Dexamethasone Sodium Phosphate	38
Dexmedetomidine	38
Dexmedetomidine hydrochloride	36
Dextrose	44
Diphenhydramine	106
Dirlotapide	37
Doxycycline	90
Enalapril Maleate	26
Enrofloxacin	139
Etodolac	53
Famotidine	145
Fenbendazole	26
Fentanyl	30
Firocoxib	237
Fluoxetine hydrochloride	20
Fluralaner	219
Frunevetmab	28
Furosemide	29
Gabapentin	186
Grapiprant	126
Hydromorphone	39
Ilunocitinib	53
Imidacloprid + Moxidectin	20
Insulin	31
Isoflurane	74
Ivermectin	68
Ivermectin + Pyrantel Pamoate	144
Ketamine Hydrochloride	41
Ketoconazole	43
Levothyroxine sodium	43
Lidocaine	23
Lotilaner	28
Lufenuron + Milbemycin Oxime	61
Marbofloxacin	39
Maropitant	534
Melarsomine Dihydrochloride	107
Meloxicam	238
Methadone	23
Metoclopramide	62
Metronidazole	162
Midazolam	48
Milbemycin Oxime	68
Milbemycin Oxime + Praziquantel	57
Milbemycin Oxime + Spinosad	181
Mirtazapine	41
Moxidectin	315
Nitenpyram	20
Oclacitinib	432
Omeprazole	56
Ondansetron	66
Oxibendazole	50
Polysulfated Glycosaminoglycan	59
Prednisolone	50
Prednisolone + Trimeprazine Tartrate	21
Prednisone	152
Propofol	71
Pyrantel Pamoate	32
Pyrantel Pamoate + Sarolaner	44
Robenacoxib	48
Sarolaner	25
Selamectin	113
Sodium Chloride	25
Spinosad	101
Sucralfate	95
Toceranib Phosphate	40
Tramadol	106
Trazodone	28
Trilostane	84
Vitamin E	34

The openFDA records give the value "MSK" for the brand name and for the manufacturer name of each drug. FDA says that MSK means "masked". So the site cannot count a report for a brand. A report can name more than one drug.

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another.
The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources.
FDA Center for Veterinary Medicine. Source: Adverse Event Reports for Animal Drugs and Devices

Ingredients, all combinations

The list has every active ingredient with 20 or more reports that list this sign, in order of name. It has 92 ingredients.

Show the 92 ingredients

Reports by species

Dog91.1%5,596
Cat7.5%458
Horse1.1%65
Cattle0.2%14
Bobcatunder 0.1%1
Donkeyunder 0.1%1

The share is of the 6,141 reports that list this sign. The sign is in 0.6% of all reports about the species dog. The sign is in 0.3% of all reports about the species cat.

Reports by month and by year

Reports for each month, Jul 2021 to Jun 2026. The month is the month in which FDA received the report.

FDA says that a report can take 3 to 6 months to reach the public data. The newest months can get more reports in a later update.

Reports that list Hypoalbuminaemia, by the year in which FDA received them
Year	Reports
2026	174
2025	255
2024	289
2023	134
2022	126
2021	118
2020	151
2019	183
2018	246
2017	290
2016	341
2015	275
2014	232
2013	187
2012	158
2011	181
2010	236
2009	204
2008	280
2007	302
2006	271
2005	268
2004	346
2003	225
2002	112
2001	88
2000	169
1999	127
1998	94
1997	15
1996	2
1995	4
1992	2
1991	1
1990	3
1989	9
1988	17
1987	26

What these reports record

Outcome at the time of the report

Reports with this sign
All reports

Recovered/Normal4.9%299, All reports: 20.7%
Recovered with Sequela[recovered, with a lasting effect]0.9%58, All reports: 2.3%
Ongoing20.5%1,258, All reports: 17.4%
Died26.4%1,623, All reports: 4.9%
Euthanized10.4%637, All reports: 1.5%
Outcome Unknown9%553, All reports: 22.7%

An outcome in a report is not proof that the drug caused it. The person who sends the report gives the outcome. Each share is of the 6,141 reports that list this sign.

Age of the animal

Reports with this sign
All reports

Under 1 year6.3%389, All reports: 9.5%
1 to 3 years13.8%849, All reports: 23.9%
4 to 7 years28.6%1,759, All reports: 20.2%
8 to 11 years33.7%2,070, All reports: 15.4%
12 years and over16%983, All reports: 10.7%
Age not given1.5%91, All reports: 20.3%

The outcome is for the full report, not for this sign only.

Next in the A to Z list of signs

All clinical signs

Cite this page

Pet Drug Reports. Hypoalbuminaemia: adverse event reports for animal drugs. https://petdrugreports.com/reaction/hypoalbuminaemia/ Source: FDA Center for Veterinary Medicine, openFDA Animal and Veterinary adverse event reports, export of 30 Oct 2026. Reports received through 26 Jun 2026.

Where the data come from

The counts come from the openFDA Animal and Veterinary adverse event files, export of 30 Oct 2026. The files have the reports that the FDA Center for Veterinary Medicine received through 26 Jun 2026. The files mask brand and manufacturer names. The site counts a drug by the active ingredients that each record gives, and gives no count to a brand, an application or a company. Ingredient names and the lists of approved products follow the FDA Green Book of 2 Nov 2026. The site counts the different spellings of one VeDDRA term together.

The site does not publish report text, lot numbers or details of a reporter. FDA's record is the authority. See how the site counts reports, the data sources and the corrections page.

Questions about this sign

What does this term mean in a report?: In plain words: low blood albumin. It is a term from VeDDRA, the list of terms that FDA and drug companies use to code a report. The person who coded the report selected the term.
How does the count of the latest 12 months compare with the 12 months before?: FDA received 303 reports in the 12 months to June 2026. It received 257 reports in the 12 months before. FDA says that a report can take 3 to 6 months to reach the public data. The newest months can get more reports in a later update.
How many of these reports have a serious flag?: Of the 3,029 reports that say if the event was serious, 74.9% have the serious flag. The person who sends a report sets the flag.
Does a drug in the table cause this sign?: The reports do not show that. A report can name more than one drug. FDA states this about the data.
When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event.
The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources.
FDA Center for Veterinary Medicine. Source: Adverse Event Reports for Animal Drugs and Devices