Recumbency: in adverse event reports for animal drugs

Clinical sign, a VeDDRA term

In plain words: lying down and unable or unwilling to rise.

Read this first. FDA says this about the data:

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another. When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event. This dataset should not be the sole source of information for clinical decision-making or other assumptions about the safety or effectiveness of a product. The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources.
FDA Center for Veterinary Medicine publishes these words. Source: Adverse Event Reports for Animal Drugs and Devices, read on 2 Oct 2026. The data have the reports that FDA received through 26 Jun 2026.

This page is not veterinary advice. For an animal that is ill, speak to a veterinarian.

Contacting a veterinarian How to report to FDA

From January 1987 to June 2026, FDA received 7,129 adverse event reports for animal drugs that list this sign. That is 0.5% of the 1,378,761 reports that FDA received from January 1987 to June 2026. In the 12 months to June 2026, FDA received 150 reports that list this sign.

Of the 7,129 reports, 56.1% are about dogs. A report can list more than one sign and more than one drug. A report is not proof that a drug caused a sign.

By number of reports in all years, this sign is number 90 of 1,149 clinical signs with a page. Reports that list this sign fell by 17.6% in the 12 months to June 2026, compared with the 12 months before. Reports for all animal drugs fell by 4.6% in the same periods. The newest months can get more reports in a later update. Reports about dogs are 56.1% of the reports that list this sign, and 72.6% of all reports.

Search engines list a sign page with 3,000 reports or more in all years. The page also needs 300 reports or more in the 12 months to June 2026. This page is under one of these numbers. The site keeps the page and keeps it out of search engines.

Drug pages with reports that list this sign

The table has every drug page with 20 or more reports that list this sign, in order of name. No count decides which drug is in the table. The table has 78 drug pages.

Show the 78 drug pages

Drug pages with 20 or more reports that list this sign, in order of name
Active ingredients	Reports that list the sign
Afoxolaner	150
Amoxicillin	49
Atipamezole Hydrochloride	37
Bedinvetmab	153
Buprenorphine	40
Butorphanol Tartrate	75
Carprofen	688
Cefovecin sodium	131
Cefpodoxime proxetil	30
Ceftiofur Crystalline Free Acid	44
Clorsulon + Ivermectin	29
Cyclosporine	64
Deracoxib	262
Desoxycorticosterone Pivalate	22
Detomidine Hydrochloride	40
Dexamethasone	56
Dexmedetomidine hydrochloride	41
Dinoprost Tromethamine	42
Diphenhydramine	50
Dirlotapide	20
Doramectin	61
Doxycycline	24
Enrofloxacin	64
Eprinomectin	63
Famotidine	27
Fenbendazole	46
Firocoxib	158
Florfenicol	32
Flunixin Meglumine	40
Fluralaner	155
Gabapentin	88
Grapiprant	30
Imidacloprid + Moxidectin	35
Insulin	74
Isoflurane	28
Ivermectin	464
Ivermectin + Praziquantel	89
Ivermectin + Pyrantel Pamoate	174
Ketamine Hydrochloride	50
Lincomycin Hydrochloride Monohydrate + Spectinomycin Sulfate Tetrahydrate	29
Lufenuron	20
Lufenuron + Milbemycin Oxime	52
Maropitant	167
Medetomidine	26
Melarsomine Dihydrochloride	261
Meloxicam	159
Methylprednisolone Acetate	24
Metronidazole	30
Midazolam	24
Milbemycin Oxime	107
Milbemycin Oxime + Spinosad	132
Monensin	334
Moxidectin	592
Moxidectin + Praziquantel	29
Narasin	34
Nitazoxanide	25
Nitenpyram	74
Oclacitinib	39
Oxytetracycline	37
Pergolide mesylate	22
Pimobendan	25
Polysulfated Glycosaminoglycan	55
Prednisone	46
Propofol	27
Pyrantel Pamoate	51
Pyrantel Pamoate + Sarolaner	33
Sarolaner	28
Selamectin	177
Selegiline Hydrochloride	29
Spinosad	142
Tiletamine Hydrochloride + Zolazepam Hydrochloride	61
Tilmicosin Phosphate	103
Tramadol	29
Trilostane	41
Tulathromycin	41
Tylosin	30
Vitamin E	47
Xylazine	27

The openFDA records give the value "MSK" for the brand name and for the manufacturer name of each drug. FDA says that MSK means "masked". So the site cannot count a report for a brand. A report can name more than one drug.

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another.
The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources.
FDA Center for Veterinary Medicine. Source: Adverse Event Reports for Animal Drugs and Devices

Ingredients, all combinations

The list has every active ingredient with 20 or more reports that list this sign, in order of name. It has 80 ingredients.

Show the 80 ingredients

Reports by species

Dog56.1%4,000
Cattle14.7%1,048
Cat11.7%831
Horse9.9%708
Pig2.8%201
Turkey1.8%126

The share is of the 7,129 reports that list this sign. The sign is in 0.4% of all reports about the species dog. The sign is in 3.3% of all reports about the species cattle.

Reports by month and by year

Reports for each month, Jul 2021 to Jun 2026. The month is the month in which FDA received the report.

FDA says that a report can take 3 to 6 months to reach the public data. The newest months can get more reports in a later update.

Reports that list Recumbency, by the year in which FDA received them
Year	Reports
2026	67
2025	179
2024	166
2023	134
2022	94
2021	115
2020	145
2019	151
2018	200
2017	208
2016	222
2015	199
2014	163
2013	168
2012	210
2011	369
2010	428
2009	388
2008	366
2007	301
2006	327
2005	270
2004	364
2003	279
2002	217
2001	196
2000	243
1999	205
1998	181
1997	106
1996	66
1995	57
1994	45
1993	24
1992	34
1991	25
1990	33
1989	96
1988	44
1987	44

What these reports record

Outcome at the time of the report

Reports with this sign
All reports

Recovered/Normal7.9%565, All reports: 20.7%
Recovered with Sequela[recovered, with a lasting effect]0.7%49, All reports: 2.3%
Ongoing6.3%448, All reports: 17.4%
Died43.3%3,090, All reports: 4.9%
Euthanized6.6%473, All reports: 1.5%
Outcome Unknown6.1%437, All reports: 22.7%

An outcome in a report is not proof that the drug caused it. The person who sends the report gives the outcome. Each share is of the 7,129 reports that list this sign.

Age of the animal

Reports with this sign
All reports

Under 1 year18.1%1,289, All reports: 9.5%
1 to 3 years16.6%1,186, All reports: 23.9%
4 to 7 years17.2%1,223, All reports: 20.2%
8 to 11 years17.3%1,231, All reports: 15.4%
12 years and over16.7%1,189, All reports: 10.7%
Age not given14.2%1,011, All reports: 20.3%

The outcome is for the full report, not for this sign only.

Next in the A to Z list of signs

All clinical signs

Cite this page

Pet Drug Reports. Recumbency: adverse event reports for animal drugs. https://petdrugreports.com/reaction/recumbency/ Source: FDA Center for Veterinary Medicine, openFDA Animal and Veterinary adverse event reports, export of 30 Oct 2026. Reports received through 26 Jun 2026.

Where the data come from

The counts come from the openFDA Animal and Veterinary adverse event files, export of 30 Oct 2026. The files have the reports that the FDA Center for Veterinary Medicine received through 26 Jun 2026. The files mask brand and manufacturer names. The site counts a drug by the active ingredients that each record gives, and gives no count to a brand, an application or a company. Ingredient names and the lists of approved products follow the FDA Green Book of 2 Nov 2026. The site counts the different spellings of one VeDDRA term together.

The site does not publish report text, lot numbers or details of a reporter. FDA's record is the authority. See how the site counts reports, the data sources and the corrections page.

Questions about this sign

What does this term mean in a report?: In plain words: lying down and unable or unwilling to rise. It is a term from VeDDRA, the list of terms that FDA and drug companies use to code a report. The person who coded the report selected the term.
How does the count of the latest 12 months compare with the 12 months before?: FDA received 150 reports in the 12 months to June 2026. It received 182 reports in the 12 months before. FDA says that a report can take 3 to 6 months to reach the public data. The newest months can get more reports in a later update.
How many of these reports have a serious flag?: Of the 2,274 reports that say if the event was serious, 84.9% have the serious flag. The person who sends a report sets the flag.
Does a drug in the table cause this sign?: The reports do not show that. A report can name more than one drug. FDA states this about the data.
When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event.
The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources.
FDA Center for Veterinary Medicine. Source: Adverse Event Reports for Animal Drugs and Devices