Abnormal ultrasound finding: in adverse event reports for animal drugs

Clinical sign, a VeDDRA term

Read this first. FDA says this about the data:

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another. When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event. This dataset should not be the sole source of information for clinical decision-making or other assumptions about the safety or effectiveness of a product. The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources.
FDA Center for Veterinary Medicine publishes these words. Source: Adverse Event Reports for Animal Drugs and Devices, read on 2 Oct 2026. The data have the reports that FDA received through 26 Jun 2026.

This page is not veterinary advice. For an animal that is ill, speak to a veterinarian.

Contacting a veterinarian How to report to FDA

From November 1997 to June 2026, FDA received 6,313 adverse event reports for animal drugs that list this sign. That is 0.5% of the 1,378,761 reports that FDA received from January 1987 to June 2026. In the 12 months to June 2026, FDA received 406 reports that list this sign.

Of the 6,313 reports, 84.6% are about dogs. A report can list more than one sign and more than one drug. A report is not proof that a drug caused a sign.

By number of reports in all years, this sign is number 99 of 1,149 clinical signs with a page. Reports that list this sign fell by 11.2% in the 12 months to June 2026, compared with the 12 months before. Reports for all animal drugs fell by 4.6% in the same periods. The newest months can get more reports in a later update. Reports about dogs are 84.6% of the reports that list this sign, and 72.6% of all reports.

Drug pages with reports that list this sign

The table has every drug page with 20 or more reports that list this sign, in order of name. No count decides which drug is in the table. The table has 95 drug pages.

Show the 95 drug pages

Drug pages with 20 or more reports that list this sign, in order of name
Active ingredients	Reports that list the sign
Acepromazine Maleate	37
Afoxolaner	162
Amlodipine	22
Amoxicillin	143
Amoxicillin + Clavulanate Potassium	88
Amoxicillin Trihydrate + Clavulanate Potassium	86
Ampicillin Sodium	50
Atipamezole Hydrochloride	41
Atropine	33
Bedinvetmab	266
Bexagliflozin	70
Buprenorphine	175
Butorphanol Tartrate	131
Capromorelin	68
Carprofen	1,198
Cefovecin sodium	232
Cefpodoxime proxetil	114
Ceftiofur Crystalline Free Acid	42
Cephalexin	47
Clindamycin	45
Clomipramine Hydrochloride	31
Cyclosporine	238
Deracoxib	527
Desoxycorticosterone Pivalate	25
Dexamethasone	92
Dexamethasone Sodium Phosphate	34
Dexmedetomidine	41
Dexmedetomidine hydrochloride	65
Dextrose	28
Diazepam	20
Diphenhydramine	92
Doxycycline	117
Enalapril Maleate	33
Enrofloxacin	155
Estriol	25
Famotidine	202
Fentanyl	32
Firocoxib	203
Fluralaner	303
Frunevetmab	72
Furosemide	45
Gabapentin	303
Grapiprant	194
Hydromorphone	46
Ilunocitinib	40
Imidacloprid	24
Imidacloprid + Moxidectin	36
Insulin	116
Isoflurane	93
Ivermectin	59
Ivermectin + Pyrantel Pamoate	203
Ketamine Hydrochloride	41
Ketoconazole	29
Levothyroxine sodium	75
Lidocaine	26
Lotilaner	32
Lufenuron + Milbemycin Oxime	76
Marbofloxacin	30
Maropitant	721
Melarsomine Dihydrochloride	64
Meloxicam	230
Methadone	23
Methylprednisolone Acetate	30
Metoclopramide	60
Metronidazole	198
Midazolam	50
Milbemycin Oxime	59
Milbemycin Oxime + Praziquantel	67
Milbemycin Oxime + Spinosad	240
Mirtazapine	82
Moxidectin	269
Nitenpyram	24
Oclacitinib	436
Omeprazole	75
Ondansetron	95
Pimobendan	60
Polysulfated Glycosaminoglycan	105
Prednisolone	62
Prednisolone + Trimeprazine Tartrate	37
Prednisone	179
Propofol	80
Pyrantel Pamoate + Sarolaner	58
Robenacoxib	51
Sarolaner	42
Selamectin	92
Sevoflurane	21
Sodium Chloride	25
Spinosad	103
Sucralfate	119
Tramadol	190
Trazodone	54
Trilostane	459
Ursodiol	65
Velagliflozin	92
Vitamin E	94

The openFDA records give the value "MSK" for the brand name and for the manufacturer name of each drug. FDA says that MSK means "masked". So the site cannot count a report for a brand. A report can name more than one drug.

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another.
The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources.
FDA Center for Veterinary Medicine. Source: Adverse Event Reports for Animal Drugs and Devices

Ingredients, all combinations

The list has every active ingredient with 20 or more reports that list this sign, in order of name. It has 97 ingredients.

Show the 97 ingredients

Reports by species

Dog84.6%5,339
Cat12.9%817
Horse2.3%143
Cattle0.1%4
Human exposure0.1%4
Pigunder 0.1%2

The share is of the 6,313 reports that list this sign. The sign is in 0.5% of all reports about the species dog. The sign is in 0.5% of all reports about the species cat.

Reports by month and by year

Reports for each month, Jul 2021 to Jun 2026. The month is the month in which FDA received the report.

FDA says that a report can take 3 to 6 months to reach the public data. The newest months can get more reports in a later update.

Reports that list Abnormal ultrasound finding, by the year in which FDA received them
Year	Reports
2026	224
2025	419
2024	372
2023	235
2022	193
2021	177
2020	205
2019	275
2018	371
2017	400
2016	429
2015	412
2014	364
2013	250
2012	224
2011	238
2010	195
2009	189
2008	197
2007	185
2006	172
2005	125
2004	171
2003	96
2002	47
2001	37
2000	34
1999	43
1998	33
1997	1

What these reports record

Outcome at the time of the report

Reports with this sign
All reports

Recovered/Normal7.3%463, All reports: 20.7%
Recovered with Sequela[recovered, with a lasting effect]1.9%118, All reports: 2.3%
Ongoing28.3%1,786, All reports: 17.4%
Died17.5%1,104, All reports: 4.9%
Euthanized15.4%972, All reports: 1.5%
Outcome Unknown13.8%870, All reports: 22.7%

An outcome in a report is not proof that the drug caused it. The person who sends the report gives the outcome. Each share is of the 6,313 reports that list this sign.

Age of the animal

Reports with this sign
All reports

Under 1 year3.2%200, All reports: 9.5%
1 to 3 years10.4%656, All reports: 23.9%
4 to 7 years22.4%1,413, All reports: 20.2%
8 to 11 years38.1%2,403, All reports: 15.4%
12 years and over25%1,581, All reports: 10.7%
Age not given1%60, All reports: 20.3%

The outcome is for the full report, not for this sign only.

Next in the A to Z list of signs

Abnormal radiograph finding
Abnormal red blood cell
Abnormal stool colouration
Abnormal test result
Abnormal urine odour
Abortion
Abscess NOS[NOS: not otherwise specified]
Accidental drug intake by child

All clinical signs

Cite this page

Pet Drug Reports. Abnormal ultrasound finding: adverse event reports for animal drugs. https://petdrugreports.com/reaction/abnormal-ultrasound-finding/ Source: FDA Center for Veterinary Medicine, openFDA Animal and Veterinary adverse event reports, export of 30 Oct 2026. Reports received through 26 Jun 2026.

Where the data come from

The counts come from the openFDA Animal and Veterinary adverse event files, export of 30 Oct 2026. The files have the reports that the FDA Center for Veterinary Medicine received through 26 Jun 2026. The files mask brand and manufacturer names. The site counts a drug by the active ingredients that each record gives, and gives no count to a brand, an application or a company. Ingredient names and the lists of approved products follow the FDA Green Book of 2 Nov 2026. The site counts the different spellings of one VeDDRA term together.

The site does not publish report text, lot numbers or details of a reporter. FDA's record is the authority. See how the site counts reports, the data sources and the corrections page.

Questions about this sign

What does this term mean in a report?: It is a term from VeDDRA, the list of terms that FDA and drug companies use to code a report. The person who coded the report selected the term.
How does the count of the latest 12 months compare with the 12 months before?: FDA received 406 reports in the 12 months to June 2026. It received 457 reports in the 12 months before. FDA says that a report can take 3 to 6 months to reach the public data. The newest months can get more reports in a later update.
How many of these reports have a serious flag?: Of the 4,477 reports that say if the event was serious, 80% have the serious flag. The person who sends a report sets the flag.
Does a drug in the table cause this sign?: The reports do not show that. A report can name more than one drug. FDA states this about the data.
When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event.
The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources.
FDA Center for Veterinary Medicine. Source: Adverse Event Reports for Animal Drugs and Devices