Manchester Terrier: adverse event reports for animal drugs

Breed of dog

The FDA breed label is "Terrier - Manchester". The count has only the reports that give this one breed.

Read this first. FDA says this about the data:

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another. When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event. This dataset should not be the sole source of information for clinical decision-making or other assumptions about the safety or effectiveness of a product. The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources.
FDA Center for Veterinary Medicine publishes these words. Source: Adverse Event Reports for Animal Drugs and Devices, read on 2 Oct 2026. The data have the reports that FDA received through 26 Jun 2026.

This page is not veterinary advice. For an animal that is ill, speak to a veterinarian.

Contacting a veterinarian How to report to FDA

From August 1988 to June 2026, FDA received 172 reports that give the breed Manchester Terrier. That is under 0.1% of the reports about dogs. In the 12 months to June 2026, FDA received 6 reports for this breed.

The count has only the reports that give this one breed. Reports about crossbred animals are in the count for the species. The signs that appear in the largest number of the 172 reports are "Vomiting", "Lethargy" and "Diarrhoea". A report is not proof that a drug caused a sign.

By number of reports in all years, this breed is number 149 of 167 breeds of dogs with a page. Fewer than 20 reports gave this breed in the 12 months before June 2026, so this page gives no change. The sign "Vomiting" is in 23.3% of the reports that give this breed, and in 19.6% of the reports about dogs.

Search engines list a breed page with 1,500 reports or more in all years. The page also needs 30 reports or more in the 12 months to June 2026. This page is under one of these numbers. The site keeps the page and keeps it out of search engines.

Drug pages with reports for this breed

The table has every drug page with 5 or more reports that give this breed, in order of name. No count decides which drug is in the table. The table has 10 drug pages.

Drug pages with 5 or more reports that give the breed Manchester Terrier, in order of name
Active ingredients	Reports that give this breed
Afoxolaner	5
Carprofen	5
Fluralaner	10
Ivermectin + Pyrantel Pamoate	22
Lufenuron + Milbemycin Oxime	8
Milbemycin Oxime + Spinosad	27
Moxidectin	10
Pyrantel Pamoate + Sarolaner	5
Selamectin	8
Spinosad	8

The openFDA records give the value "MSK" for the brand name and for the manufacturer name of each drug. FDA says that MSK means "masked". So the site cannot count a report for a brand.

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another.
Commonly used products may have a higher number of reported adverse events due to the higher total number of animals being given the product.
FDA Center for Veterinary Medicine. Source: Adverse Event Reports for Animal Drugs and Devices

Signs that the reports list

A sign is a coded term from the report. The words in brackets are a plain gloss of the term. The percentage is the share of the 172 reports that list the sign.

The sign that is in the largest number of the reports comes first.

Vomiting23.3%40 reports
Lethargy[unusually tired or inactive]11.6%20 reports
Diarrhoea[diarrhea]10.5%18 reports
Emesis[vomiting]5.2%9 reports
Ineffective, heartworm larvae[legacy FDA term: the product did not have the expected effect (heartworm larvae)]4.7%8 reports
Lack of efficacy (endoparasite) - hookworm[the product did not have the expected effect: hookworms]4.7%8 reports
Ataxia[unsteady, uncoordinated movement]4.1%7 reports
Depression[dull, quiet or withdrawn]4.1%7 reports
Not eating4.1%7 reports
Lack of efficacy (endoparasite) - heartworm[the product did not have the expected effect: heartworm]3.5%6 reports
Lack of efficacy - NOS[the product did not have the expected effect]3.5%6 reports
Weakness3.5%6 reports
Weight loss3.5%6 reports
Accidental exposure[exposure that was not intended]2.9%5 reports

Show the next 11 signs

Anorexia[not eating]2.9%5 reports
Death by euthanasia[the animal was euthanized]2.9%5 reports
Elevated serum alkaline phosphatase (SAP)[a liver and bone enzyme above the normal range]2.9%5 reports
Emesis (multiple)[vomiting more than once]2.9%5 reports
Lack of efficacy (ectoparasite) - flea[the product did not have the expected effect: fleas]2.9%5 reports
Seizure NOS[seizure, type not specified]2.9%5 reports
Trembling2.9%5 reports
Bloody diarrhoea[diarrhea with blood]2.3%4 reports
Death2.3%4 reports
Injection site swelling[swelling where the injection was given]2.3%4 reports
Overdose[more than the labelled amount was given]2.3%4 reports

What the reports record

Age of the animal

Manchester Terrier reports
All reports about dogs

Under 1 year5.2%9, All reports about dogs: 10.3%
1 to 3 years24.4%42, All reports about dogs: 29.2%
4 to 7 years29.1%50, All reports about dogs: 24.5%
8 to 11 years23.3%40, All reports about dogs: 18.4%
12 years and over14.5%25, All reports about dogs: 10.1%
Age not given3.5%6, All reports about dogs: 7.6%

Weight of the animal

Manchester Terrier reports
All reports about dogs

Under 5 kg (11 lb)25%43, All reports about dogs: 11.6%
5 to 9.9 kg (11 to 22 lb)44.2%76, All reports about dogs: 18.7%
10 to 24.9 kg (22 to 55 lb)27.3%47, All reports about dogs: 27.5%
25 to 44.9 kg (55 to 99 lb)1.2%2, All reports about dogs: 30.4%
45 kg and over (99 lb and over)0%0, All reports about dogs: 3.9%
Weight not given2.3%4, All reports about dogs: 7.9%

Outcome at the time of the report

Recovered/Normal22.1%38
Recovered with Sequela[recovered, with a lasting effect]3.5%6
Ongoing19.2%33
Died2.9%5
Euthanized2.3%4
Outcome Unknown20.9%36

An outcome in a report is not proof that the drug caused it. The person who sends the report gives the outcome. Each share is of the 172 reports that give this breed.

Each share of age and weight is of the 172 reports that give this breed. The thin bar is the same share in the 1,001,350 reports about dogs.

Reports by month and by year

Reports for each month, Jul 2021 to Jun 2026. The month is the month in which FDA received the report.

FDA says that a report can take 3 to 6 months to reach the public data. The newest months can get more reports in a later update.

Reports that give the breed Manchester Terrier, by the year in which FDA received them
Year	Reports
2026	3
2025	6
2024	7
2023	3
2022	5
2021	6
2020	7
2019	9
2018	4
2017	16
2016	9
2015	13
2014	4
2013	12
2012	11
2011	11
2010	6
2009	5
2008	5
2007	4
2006	4
2005	3
2004	2
2003	3
2002	3
2001	2
2000	3
1999	2
1998	1
1996	1
1994	1
1988	1

Next in the A to Z list of breeds

All reports about dogs. All breeds

Cite this page

Pet Drug Reports. Manchester Terrier: adverse event reports for animal drugs. https://petdrugreports.com/breed/dog/manchester-terrier/ Source: FDA Center for Veterinary Medicine, openFDA Animal and Veterinary adverse event reports, export of 30 Oct 2026. Reports received through 26 Jun 2026.

Where the data come from

The counts come from the openFDA Animal and Veterinary adverse event files, export of 30 Oct 2026. The files have the reports that the FDA Center for Veterinary Medicine received through 26 Jun 2026. The files mask brand and manufacturer names. The site counts a drug by the active ingredients that each record gives, and gives no count to a brand, an application or a company. Ingredient names and the lists of approved products follow the FDA Green Book of 2 Nov 2026. The site puts the FDA breed label in the usual order of the words.

The site does not publish report text, lot numbers or details of a reporter. FDA's record is the authority. See how the site counts reports, the data sources and the corrections page.

Questions about these reports

What ages are the animals in the reports?: The figures are shares of the 172 reports about this breed received from August 1988 to June 2026. 29.1% give an age of 4 to 7 years. 24.4% give an age of 1 to 3 years. 3.5% give no age.
How does the count of the latest 12 months compare with the 12 months before?: FDA received 6 reports in the 12 months to June 2026. It received 9 reports in the 12 months before. FDA says that a report can take 3 to 6 months to reach the public data. The newest months can get more reports in a later update.
Why are crossbred animals not in the count?: The site counts a report for a breed only when the report gives one breed. A report for a crossbred animal can give more than one breed, and a count for each breed would count the report more than once. The reports about crossbred animals are in the count for dogs.
Do the reports show that this breed reacts more to a drug?: No. The reports do not give the number of animals of the breed. FDA states this about the data.
An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another.
FDA Center for Veterinary Medicine. Source: Adverse Event Reports for Animal Drugs and Devices