Breed · Cattle
Simmental: adverse event reports
FDA breed label "Simmental" · single-breed animals only
FDA's database holds 186 reports where the animal's breed is given as "Simmental", shown here as Simmental: 0.6% of reports about cattle. Reports on crossbred animals are left out of breed pages.
4 reports arrived in the 12 months to March 2026, down 20% from 5 in the 12 months before. A breed's count mostly mirrors how common the breed is; registration and ownership figures by breed are not public data, so no per-animal rate can be given.
By active ingredient, the drugs named most often are ivermectin, doramectin and dinoprost tromethamine. Ivermectin is named in 19.4% of this breed's reports, a larger share than in reports about all cattle (6.9%).
The terms listed most often are death (31.2%), lack of efficacy (ectoparasite) - lice (12.9%) and recumbency (8.6%). Death appears in 31.2% of reports, about the same share as in all cattle reports (29.4%). 58.9% of reports stating seriousness were classed as serious, against 58.4% for cattle overall.
Drugs named most often, by active ingredient
| Active ingredients recorded for the drug | Reports | Share of Simmental reports | Share of all cattle reports |
|---|---|---|---|
| Ivermectin | 36 | 19.4% | 6.9% |
| Doramectin | 30 | 16.1% | 10.3% |
| Dinoprost Tromethamine | 12 | 6.5% | 2.9% |
| Progesterone | 11 | 5.9% | 1.5% |
| Moxidectin | 10 | 5.4% | 4.2% |
| Tilmicosin Phosphate | 10 | 5.4% | 2.6% |
| Eprinomectin | 8 | 4.3% | 4.8% |
| Oxytetracycline | 7 | 3.8% | 2.1% |
| Ceftiofur Crystalline Free Acid | 6 | 3.2% | 3.1% |
| Levamisole | 6 | 3.2% | 0.4% |
| Tulathromycin | 6 | 3.2% | 7.3% |
| Florfenicol | 4 | 2.2% | 1.6% |
| Florfenicol + Flunixin | 4 | 2.2% | 0.9% |
| Flunixin | 4 | 2.2% | 0.3% |
| Flunixin Meglumine | 4 | 2.2% | 0.9% |
| Estradiol | 3 | 1.6% | 0.8% |
| Tildipirosin | 3 | 1.6% | 1.3% |
| Vitamin E | 3 | 1.6% | 0.8% |
| Clorsulon + Ivermectin | 2 | 1.1% | 1% |
| Danofloxacin | 2 | 1.1% | 0.4% |
Ordered by report count. Differences from the species column often come from body size (which drugs a breed is prescribed) and from how common the breed was in the years a drug sold most. FDA states that these data cannot be used to estimate risk or to compare one product with another. Brand and manufacturer names are masked by FDA in these records.
Signs listed in reports
share of Simmental reports listing the termall cattle reports
- Death31.2%58
- Lack of efficacy (ectoparasite) - lice[the product did not have the expected effect: lice]12.9%24
- Recumbency[lying down and unable or unwilling to rise]8.6%16
- Anaphylaxis[sudden severe allergic-type reaction]7.5%14
- Lack of efficacy - NOS[the product did not have the expected effect]7%13
- Ataxia[unsteady, uncoordinated movement]5.9%11
- Hypersalivation[drooling]5.9%11
- Ineffective, estrus synchroniz[legacy FDA term: the product did not have the expected effect (estrus synchroniz)]5.9%11
- Injection site swelling[swelling where the injection was given]5.9%11
- Pruritus[itching]5.9%11
- Alopecia NOS[hair loss, type not specified]5.4%10
- Ineffective, parasite(s) NOS[legacy FDA term: the product did not have the expected effect (parasite(s) nos)]5.4%10
- Anorexia[not eating]4.3%8
- Depression[dull, quiet or withdrawn]4.3%8
- Weight loss4.3%8
- Death by euthanasia[the animal was euthanized]3.2%6
- Diarrhoea[diarrhea]3.2%6
- Ineffective, lice biting[legacy FDA term: the product did not have the expected effect (lice biting)]3.2%6
- Abortion2.7%5
- Staggering2.7%5
- Systemic disorder NOS[NOS: not otherwise specified]2.7%5
- Collapse2.2%4
- Dyspnoea[difficulty breathing]2.2%4
- Lack of efficacy (lice)[the product did not have the expected effect: lice]2.2%4
- Lameness2.2%4
Age and weight
Age of the animal
Weight of the animal
Coloured bar: Simmental reports. Grey bar: all cattle reports.
Trend and outcomes
Reports by month FDA received them. The newest months are incomplete because FDA posts reports with a delay of three to six months.
Outcome recorded in the report
Beside all cattle
| Measure | Simmental | All cattle |
|---|---|---|
| Reports | 186 | 31,229 |
| Latest 12 months | 4 | 644 |
| Classed serious, of reports stating it | 58.9% | 58.4% |
| Death or euthanasia recorded, per 1,000 reports | 371 | 368 |
Questions about Simmental reports
How many FDA adverse event reports involve Simmentals?
186 reports through March 2026, 0.6% of reports about cattle; 4 in the latest 12 months.
Which drugs are named most often in Simmental reports?
By active ingredient: ivermectin (36), doramectin (30), dinoprost tromethamine (12), progesterone (11) and moxidectin (10). Brands are masked in the public data.
What signs are reported most for this breed?
death (31.2%), lack of efficacy (ectoparasite) - lice (12.9%), recumbency (8.6%), anaphylaxis (7.5%) and lack of efficacy - NOS (7%).
Is the Simmental more sensitive to certain drugs?
Report counts cannot answer that. They show what was reported, not what a drug did, and they are not adjusted for how many Simmental animals exist or were treated. Breed-related drug sensitivities that are established are described on FDA-approved labels; a veterinarian is the person to ask about an individual animal.
Why are crossbreds not included?
FDA records crossbred animals with one or more component breeds. Counting them under each component would double count, so breed pages use single-breed reports only. Crossbreds remain in the species totals.
How do I report a problem?
Call the drug company using the number on the label, or send Form FDA 1932a to FDA. See the guide on how to report.
Where this comes from. Counts are built from the openFDA Animal & Veterinary adverse event bulk files released 28 Sep 2026, which hold reports FDA's Center for Veterinary Medicine received through 31 Mar 2026. openFDA masks brand and manufacturer names in these files, so drugs are counted by the active ingredients each record discloses and no figure is attributed to a brand, application or company. Ingredient names, and the separate reference lists of approved products, follow the FDA Green Book as of 1 Oct 2026. Breed names are FDA's labels rearranged into everyday order ("Simmental" becomes "Simmental"). No report text, lot numbers or reporter details are published. See the methodology and sources; FDA's record is authoritative, and corrections are handled within five working days.