Pet Drug Reports

Reported signs

Reported sign · VeDDRA term

Schirmer tear test: reports listing this term

200reports listing the term, 2018–20240% of all reports
0reports, 12 months to March 202615 in the 12 months before
74%classed serious, as reportedall reports: 38.6%
99.5%of these reports concern dogscat 0.5%

"Schirmer tear test" is a coded term listed in 200 adverse event reports received by FDA, 0% of the database. Terms come from VeDDRA, the veterinary dictionary that FDA and drug companies use to code what a reporter describes.

0 reports listed it in the 12 months to March 2026, against 15 in the 12 months before. FDA posts reports quarterly with a delay of three to six months, so the newest months are incomplete and usually grow in later releases.

By active ingredient, the drugs named most often in those reports are florfenicol + mometasone furoate + terbinafine, maropitant and ketoconazole. That order mostly follows how many reports each has overall; the table gives the term's share within each drug's own reports as well.

99.5% of the reports concern dogs and 0.5% of the reports concern cats. Of reports listing this term that state seriousness, 74% were classed as serious; 3% record a death or euthanasia among the outcomes.

Drugs named most often in these reports, by active ingredient

Active ingredients recorded for the drugReports listing the termShare of that drug's own reports
Florfenicol + Mometasone furoate + Terbinafine1562.8%
Maropitant380.2%
Ketoconazole311.3%
Betamethasone Acetate + Florfenicol + Terbinafine264.2%
Cyclosporine240.1%
Bacitracin194.6%
Prednisone190.2%
Carprofen170%
Gabapentin170.2%
Dexamethasone150.5%
Enrofloxacin150.2%
Oclacitinib130%
Amoxicillin Trihydrate + Clavulanate Potassium90.2%
Cefovecin sodium80.1%
Diphenhydramine80.2%
Meloxicam80%
Moxidectin80%
Marbofloxacin70.4%
Salicylic Acid71.6%
Atropine60.6%
Butorphanol Tartrate60.1%
Dexmedetomidine60.2%
Isoflurane60.1%
Pimobendan60.1%
Tramadol60.2%

Ordered by number of reports, which mostly tracks how many reports a drug has overall. Across the whole database the term appears in 0% of reports. A drug's presence in a report means the animal received it, not that it produced the sign; FDA states that these data cannot be used to compare one product with another. openFDA masks brand and manufacturer names in adverse event records, so the reports counted here cannot be attributed to a particular brand.

Single ingredients, pooled across combinations

Active ingredientReports listing the termShare of the ingredient's own reports
Florfenicol1811.8%
Terbinafine1812.1%
Mometasone furoate1562.7%
Maropitant380.2%
Ketoconazole361.4%
Betamethasone Acetate263.8%
Cyclosporine240.1%
Bacitracin204.1%
Prednisone190.2%
Dexamethasone180.4%
Gabapentin180.2%
Carprofen170%
Enrofloxacin170.2%
Oclacitinib130%
Bacitracin Zinc1214.8%
Clavulanate Potassium120.1%
Salicylic Acid111.5%
Polymyxin B Sulfate101.4%
Amoxicillin Trihydrate90.2%
Moxidectin90%
Cefovecin sodium80.1%
Diphenhydramine80.2%
Meloxicam80%
Orbifloxacin80.4%
Posaconazole81.6%

Species split

Dog99.5%199
Cat0.5%1

Coloured bar: share of reports listing this term. Grey bar: the species' share of all reports. The term appears in 0% of all dog reports; The term appears in 0% of all cat reports.

Trend

0611Apr 2021: 5May 2021: 3Jun 2021: 7Jul 2021: 2Aug 2021: 2Sep 2021: 4Oct 2021: 6Nov 2021: 3Dec 2021: 1Jan 2022: 12022Feb 2022: 2Mar 2022: 2Apr 2022: 2May 2022: 0Jun 2022: 1Jul 2022: 1Aug 2022: 4Sep 2022: 4Oct 2022: 2Nov 2022: 2Dec 2022: 5Jan 2023: 42023Feb 2023: 1Mar 2023: 6Apr 2023: 5May 2023: 5Jun 2023: 3Jul 2023: 4Aug 2023: 8Sep 2023: 4Oct 2023: 11Nov 2023: 3Dec 2023: 7Jan 2024: 32024Feb 2024: 7Mar 2024: 1Apr 2024: 3May 2024: 4Jun 2024: 1Jul 2024: 3Aug 2024: 1Sep 2024: 1Oct 2024: 2Nov 2024: 0Dec 2024: 0Jan 2025: 02025Feb 2025: 0Mar 2025: 0Apr 2025: 0May 2025: 0Jun 2025: 0Jul 2025: 0Aug 2025: 0Sep 2025: 0Oct 2025: 0Nov 2025: 0Dec 2025: 0Jan 2026: 02026Feb 2026: 0Mar 2026: 0

Reports by month FDA received them, five years to March 2026. The newest months are incomplete because FDA posts reports with a delay of three to six months.

031612018: 120182019: 1820192020: 2420202021: 4420212022: 2620222023: 6120232024: 262024

Outcomes and ages in these reports

Outcome recorded in the report

Recovered/Normal16.5%33
Recovered with Sequela0.5%1
Ongoing45%90
Died0%0
Euthanized3%6
Outcome Unknown35%70

Age of the animal

Under 1 year1%2
1 to 3 years18.5%37
4 to 7 years28%56
8 to 11 years36%72
12 years and over15%30
Age not given1.5%3
MeasureReports listing this termAll reports
Reports2001,357,245
Classed serious, of reports stating it74%38.6%
Death or euthanasia recorded, per 1,000 reports3063.8

Grey bars and the right-hand column are the whole database. Outcomes are as stated by the reporter and describe the report as a whole, not this term alone.

Questions about "Schirmer tear test"

What does "Schirmer tear test" mean in an adverse event report?

It is a VeDDRA dictionary term picked to code what the reporter described. The report's free-text description is not published by FDA and is not shown here.

How many reports list schirmer tear test?

200 reports through March 2026 (0% of all reports), 0 of them in the latest 12 months.

Which drugs are named most often alongside this term?

By active ingredient: florfenicol + mometasone furoate + terbinafine (156), maropitant (38), ketoconazole (31), betamethasone acetate + florfenicol + terbinafine (26) and cyclosporine (24). Drugs with many reports overall lead almost every term's list. Brands cannot be identified: openFDA masks them.

Which species are involved?

dog (99.5%) and cat (0.5%).

Does a drug appearing here mean it produced this sign?

No such conclusion can be drawn. FDA states that "there is no certainty that the reported drug or device caused the adverse event" and that the event "may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources."

My animal shows this sign. What now?

This site cannot assess an animal. A veterinarian can; for an emergency, contact a veterinary emergency clinic. See the guide on when to call a vet.

Where this comes from. Counts are built from the openFDA Animal & Veterinary adverse event bulk files released 28 Sep 2026, which hold reports FDA's Center for Veterinary Medicine received through 31 Mar 2026. openFDA masks brand and manufacturer names in these files, so drugs are counted by the active ingredients each record discloses and no figure is attributed to a brand, application or company. Ingredient names, and the separate reference lists of approved products, follow the FDA Green Book as of 1 Oct 2026. Spelling variants of the same VeDDRA term (for example with and without a cross-reference note) are pooled. No report text, lot numbers or reporter details are published. See the methodology and sources; FDA's record is authoritative, and corrections are handled within five working days.