Pet Drug Reports

Reported signs

Reported sign · VeDDRA term

Distension of abdomen: reports listing this term

2,573reports listing the term, 1987–20260.2% of all reports
130reports, 12 months to March 2026132 in the 12 months before
74.2%classed serious, as reportedall reports: 38.6%
88.8%of these reports concern dogscat 8%

"Distension of abdomen" is a coded term listed in 2,573 adverse event reports received by FDA, 0.2% of the database. Terms come from VeDDRA, the veterinary dictionary that FDA and drug companies use to code what a reporter describes.

130 reports listed it in the 12 months to March 2026, close to the 132 of the 12 months before. FDA posts reports quarterly with a delay of three to six months, so the newest months are incomplete and usually grow in later releases.

By active ingredient, the drugs named most often in those reports are carprofen, trilostane and deracoxib. That order mostly follows how many reports each has overall; the table gives the term's share within each drug's own reports as well.

88.8% of the reports concern dogs, 8% of the reports concern cats and 1.7% of the reports concern horses. Of reports listing this term that state seriousness, 74.2% were classed as serious; 38.6% record a death or euthanasia among the outcomes.

Drugs named most often in these reports, by active ingredient

Active ingredients recorded for the drugReports listing the termShare of that drug's own reports
Carprofen3960.8%
Trilostane2161.8%
Deracoxib1691.4%
Milbemycin Oxime + Spinosad1640.1%
Maropitant1330.8%
Fluralaner1090.1%
Ivermectin + Pyrantel Pamoate980.1%
Oclacitinib920.3%
Firocoxib840.9%
Bedinvetmab800.4%
Moxidectin790.1%
Meloxicam670.4%
Gabapentin660.6%
Cyclosporine650.3%
Prednisone650.7%
Spinosad610.1%
Selamectin560.1%
Tramadol561.5%
Afoxolaner550.1%
Melarsomine Dihydrochloride530.2%
Cefovecin sodium490.4%
Praziquantel + Pyrantel Pamoate460.9%
Milbemycin Oxime430.1%
Pyrantel Pamoate430.7%
Amoxicillin410.5%

Ordered by number of reports, which mostly tracks how many reports a drug has overall. Across the whole database the term appears in 0.2% of reports. A drug's presence in a report means the animal received it, not that it produced the sign; FDA states that these data cannot be used to compare one product with another. openFDA masks brand and manufacturer names in adverse event records, so the reports counted here cannot be attributed to a particular brand.

Single ingredients, pooled across combinations

Active ingredientReports listing the termShare of the ingredient's own reports
Carprofen3960.8%
Milbemycin Oxime2830.1%
Pyrantel Pamoate2660.1%
Spinosad2210.1%
Trilostane2161.8%
Praziquantel1760.2%
Deracoxib1691.4%
Ivermectin1530.1%
Maropitant1330.8%
Moxidectin1240.1%
Fluralaner1100.1%
Oclacitinib920.3%
Firocoxib840.9%
Bedinvetmab800.4%
Meloxicam670.4%
Afoxolaner660.1%
Gabapentin660.6%
Cyclosporine650.3%
Prednisone650.7%
Selamectin600.1%
Tramadol561.5%
Lufenuron530.1%
Melarsomine Dihydrochloride530.2%
Amoxicillin510.5%
Cefovecin sodium490.4%

Species split

Dog88.8%2,285
Cat8%207
Horse1.7%44
Cattle0.9%24
Goat0.1%2
Pig0.1%2

Coloured bar: share of reports listing this term. Grey bar: the species' share of all reports. The term appears in 0.2% of all dog reports; The term appears in 0.1% of all cat reports.

Trend

0816Apr 2021: 9May 2021: 4Jun 2021: 5Jul 2021: 8Aug 2021: 2Sep 2021: 7Oct 2021: 6Nov 2021: 5Dec 2021: 4Jan 2022: 62022Feb 2022: 3Mar 2022: 4Apr 2022: 13May 2022: 6Jun 2022: 2Jul 2022: 6Aug 2022: 6Sep 2022: 9Oct 2022: 6Nov 2022: 0Dec 2022: 5Jan 2023: 62023Feb 2023: 6Mar 2023: 4Apr 2023: 6May 2023: 12Jun 2023: 9Jul 2023: 5Aug 2023: 7Sep 2023: 4Oct 2023: 9Nov 2023: 10Dec 2023: 7Jan 2024: 162024Feb 2024: 12Mar 2024: 9Apr 2024: 11May 2024: 13Jun 2024: 14Jul 2024: 12Aug 2024: 6Sep 2024: 9Oct 2024: 7Nov 2024: 8Dec 2024: 16Jan 2025: 112025Feb 2025: 14Mar 2025: 11Apr 2025: 15May 2025: 11Jun 2025: 10Jul 2025: 9Aug 2025: 15Sep 2025: 10Oct 2025: 10Nov 2025: 7Dec 2025: 16Jan 2026: 132026Feb 2026: 12Mar 2026: 2

Reports by month FDA received them, five years to March 2026. The newest months are incomplete because FDA posts reports with a delay of three to six months.

0721441987: 119871988: 41989: 61991: 11994: 219941995: 11996: 21997: 111998: 2819981999: 232000: 562001: 272002: 2420022003: 532004: 822005: 652006: 10320062007: 972008: 1052009: 1142010: 10920102011: 932012: 1442013: 1322014: 10420142015: 1192016: 1252017: 1302018: 10220182019: 902020: 942021: 762022: 6620222023: 852024: 1332025: 1392026: 272026

Outcomes and ages in these reports

Outcome recorded in the report

Recovered/Normal7.7%197
Recovered with Sequela1.4%36
Ongoing14.1%362
Died26.6%684
Euthanized12.1%311
Outcome Unknown17.5%449

Age of the animal

Under 1 year11%282
1 to 3 years9.9%256
4 to 7 years21%541
8 to 11 years34.7%894
12 years and over20%514
Age not given3.3%86
MeasureReports listing this termAll reports
Reports2,5731,357,245
Classed serious, of reports stating it74.2%38.6%
Death or euthanasia recorded, per 1,000 reports386.363.8

Grey bars and the right-hand column are the whole database. Outcomes are as stated by the reporter and describe the report as a whole, not this term alone.

Questions about "Distension of abdomen"

What does "Distension of abdomen" mean in an adverse event report?

It is a VeDDRA dictionary term picked to code what the reporter described. The report's free-text description is not published by FDA and is not shown here.

How many reports list distension of abdomen?

2,573 reports through March 2026 (0.2% of all reports), 130 of them in the latest 12 months.

Which drugs are named most often alongside this term?

By active ingredient: carprofen (396), trilostane (216), deracoxib (169), milbemycin oxime + spinosad (164) and maropitant (133). Drugs with many reports overall lead almost every term's list. Brands cannot be identified: openFDA masks them.

Which species are involved?

dog (88.8%), cat (8%), horse (1.7%) and cattle (0.9%).

Does a drug appearing here mean it produced this sign?

No such conclusion can be drawn. FDA states that "there is no certainty that the reported drug or device caused the adverse event" and that the event "may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources."

My animal shows this sign. What now?

This site cannot assess an animal. A veterinarian can; for an emergency, contact a veterinary emergency clinic. See the guide on when to call a vet.

Where this comes from. Counts are built from the openFDA Animal & Veterinary adverse event bulk files released 28 Sep 2026, which hold reports FDA's Center for Veterinary Medicine received through 31 Mar 2026. openFDA masks brand and manufacturer names in these files, so drugs are counted by the active ingredients each record discloses and no figure is attributed to a brand, application or company. Ingredient names, and the separate reference lists of approved products, follow the FDA Green Book as of 30 Sep 2026. Spelling variants of the same VeDDRA term (for example with and without a cross-reference note) are pooled. No report text, lot numbers or reporter details are published. See the methodology and sources; FDA's record is authoritative, and corrections are handled within five working days.