Species

Drugs named most often, by active ingredient

Ordered by report count, which follows how widely a drug is used. FDA states that these data "cannot be used to estimate the risk associated with the product or compare one drug or device product with another". openFDA masks brand and manufacturer names in adverse event records, so the reports counted here cannot be attributed to a particular brand.

Signs listed in reports

share of donkey reports listing the termall species

1. Death14.9%21
2. Ataxia[unsteady, uncoordinated movement]9.2%13
3. No sign[no clinical sign was reported]7.1%10
4. Sneezing6.4%9
5. Anorexia[not eating]5%7
6. Depression[dull, quiet or withdrawn]5%7
7. Lethargy[unusually tired or inactive]5%7
8. Locking Mechanism Abnormal5%7
9. Recumbency[lying down and unable or unwilling to rise]5%7
10. Accidental exposure[exposure that was not intended]4.3%6
11. Application site swelling[swelling where the product was applied]4.3%6
12. Colic4.3%6
13. Lack of efficacy - NOS[the product did not have the expected effect]4.3%6
14. Lip oedema4.3%6
15. Rubbing4.3%6
16. Tongue oedema4.3%6
17. Convulsion[seizure]3.5%5
18. Hypersalivation[drooling]3.5%5
19. Blindness2.8%4
20. Cough2.8%4
21. Diarrhoea[diarrhea]2.8%4
22. Dyspnoea[difficulty breathing]2.8%4
23. Ineffective, sedation[legacy FDA term: the product did not have the expected effect (sedation)]2.8%4
24. Pneumonia[lung infection or inflammation]2.8%4
25. Seizure NOS[seizure, type not specified]2.8%4
26. Behavioural disorder NOS[behaviour change, type not specified]2.1%3
27. Hind limb paresis[weak hind legs]2.1%3
28. Impaired vision2.1%3
29. Inappetence[reduced appetite]2.1%3
30. Increased sweating2.1%3

Single ingredients, pooled across combinations

• Ivermectin42 reports · 29.8%
• Praziquantel26 reports · 18.4%
• Detomidine Hydrochloride23 reports · 16.3%
• Ceftiofur Crystalline Free Acid12 reports · 8.5%
• Moxidectin12 reports · 8.5%
• Pergolide mesylate11 reports · 7.8%
• Xylazine Hydrochloride5 reports · 3.5%
• Ketamine Hydrochloride4 reports · 2.8%
• Monensin4 reports · 2.8%
• Pyrantel Tartrate4 reports · 2.8%
• Butorphanol Tartrate3 reports · 2.1%
• Flunixin Meglumine3 reports · 2.1%
• Xylazine3 reports · 2.1%
• Ceftiofur Sodium2 reports · 1.4%
• Firocoxib2 reports · 1.4%
• Pyrimethamine2 reports · 1.4%

Age and weight

Outcomes and report types

Coloured bar: donkey reports. Grey bar: all 1,357,245 reports. Outcomes are as stated by the reporter.

Trend

Reports by month FDA received them. The newest months are incomplete because FDA posts reports with a delay of three to six months.

Where this comes from. Counts are built from the openFDA Animal & Veterinary adverse event bulk files released 28 Sep 2026, which hold reports FDA's Center for Veterinary Medicine received through 31 Mar 2026. openFDA masks brand and manufacturer names in these files, so drugs are counted by the active ingredients each record discloses and no figure is attributed to a brand, application or company. Ingredient names, and the separate reference lists of approved products, follow the FDA Green Book as of 1 Oct 2026. No report text, lot numbers or reporter details are published. See the methodology and sources; FDA's record is authoritative, and corrections are handled within five working days.