Pet Drug Reports

Retching: in adverse event reports for animal drugs

Clinical sign, a VeDDRA term

Read this first. FDA says this about the data:

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another. When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event. This dataset should not be the sole source of information for clinical decision-making or other assumptions about the safety or effectiveness of a product. The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources.

FDA Center for Veterinary Medicine publishes these words. Source: Adverse Event Reports for Animal Drugs and Devices, read on . The data have the reports that FDA received through .

This page is not veterinary advice. For an animal that is ill, speak to a veterinarian.

Contacting a veterinarianHow to report to FDA

From May 1995 to June 2026, FDA received 2,529 adverse event reports for animal drugs that list this sign. That is 0.2% of the 1,378,761 reports that FDA received from January 1987 to June 2026. In the 12 months to June 2026, FDA received 56 reports that list this sign.

Of the 2,529 reports, 86.4% are about dogs. A report can list more than one sign and more than one drug. A report is not proof that a drug caused a sign.

By number of reports in all years, this sign is number 232 of 1,149 clinical signs with a page. Reports that list this sign fell by 30.9% in the 12 months to June 2026, compared with the 12 months before. Reports for all animal drugs fell by 4.6% in the same periods. The newest months can get more reports in a later update. Reports about dogs are 86.4% of the reports that list this sign, and 72.6% of all reports.

Search engines list a sign page with 3,000 reports or more in all years. The page also needs 300 reports or more in the 12 months to June 2026. This page is under one of these numbers. The site keeps the page and keeps it out of search engines.

Drug pages with reports that list this sign

The table has every drug page with 20 or more reports that list this sign, in order of name. No count decides which drug is in the table. The table has 39 drug pages.

Show the 39 drug pages
Drug pages with 20 or more reports that list this sign, in order of name
Active ingredientsReports that list the sign
(S) - methoprene21
Afoxolaner152
Bedinvetmab37
Carprofen109
Cefovecin sodium34
Cyclosporine68
Deracoxib39
Emodepside + Praziquantel32
Enrofloxacin22
Famotidine20
Febantel + Praziquantel + Pyrantel Pamoate58
Fenbendazole59
Firocoxib30
Fluralaner172
Gabapentin33
Grapiprant30
Imidacloprid21
Imidacloprid + Moxidectin82
Ivermectin26
Ivermectin + Praziquantel + Pyrantel Pamoate34
Ivermectin + Pyrantel Pamoate167
Lotilaner24
Lufenuron + Milbemycin Oxime38
Maropitant88
Melarsomine Dihydrochloride36
Meloxicam53
Milbemycin Oxime59
Milbemycin Oxime + Praziquantel62
Milbemycin Oxime + Spinosad342
Moxidectin80
Nitenpyram49
Oclacitinib40
Praziquantel + Pyrantel Pamoate43
Prednisone23
Pyrantel Pamoate51
Pyrantel Pamoate + Sarolaner77
Sarolaner28
Selamectin76
Spinosad175

The openFDA records give the value "MSK" for the brand name and for the manufacturer name of each drug. FDA says that MSK means "masked". So the site cannot count a report for a brand. A report can name more than one drug.

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another.

The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources.

FDA Center for Veterinary Medicine. Source: Adverse Event Reports for Animal Drugs and Devices

Ingredients, all combinations

The list has every active ingredient with 20 or more reports that list this sign, in order of name. It has 33 ingredients.

Show the 33 ingredients

Reports by species

  • Dog86.4%2,186
  • Cat12.7%320
  • Human exposure0.8%19
  • Cattleunder 0.1%1
  • Horseunder 0.1%1
  • Other Mustelidsunder 0.1%1

The share is of the 2,529 reports that list this sign. The sign is in 0.2% of all reports about the species dog. The sign is in 0.2% of all reports about the species cat.

Reports by month and by year

Reports for each month, Jul 2021 to Jun 2026. The month is the month in which FDA received the report.

FDA says that a report can take 3 to 6 months to reach the public data. The newest months can get more reports in a later update.

Reports that list Retching, by the year in which FDA received them
YearReports
202639
202558
2024113
2023128
2022121
2021126
2020116
2019134
2018132
2017173
2016166
2015179
2014163
2013164
2012158
201197
201078
200965
200863
200748
200658
200534
200430
200315
200213
200119
200020
199912
19984
19972
19951

What these reports record

Outcome at the time of the report

  • Reports with this sign
  • All reports
  • Recovered/Normal31.9%808, All reports: 20.7%
  • Recovered with Sequela[recovered, with a lasting effect]2.3%58, All reports: 2.3%
  • Ongoing15.3%386, All reports: 17.4%
  • Died7.1%180, All reports: 4.9%
  • Euthanized3.2%80, All reports: 1.5%
  • Outcome Unknown21.4%542, All reports: 22.7%

An outcome in a report is not proof that the drug caused it. The person who sends the report gives the outcome. Each share is of the 2,529 reports that list this sign.

Age of the animal

  • Reports with this sign
  • All reports
  • Under 1 year16.2%409, All reports: 9.5%
  • 1 to 3 years27.2%688, All reports: 23.9%
  • 4 to 7 years21.3%538, All reports: 20.2%
  • 8 to 11 years18.9%477, All reports: 15.4%
  • 12 years and over13.4%339, All reports: 10.7%
  • Age not given3.1%78, All reports: 20.3%

The outcome is for the full report, not for this sign only.

Next in the A to Z list of signs

All clinical signs

Cite this page

Pet Drug Reports. Retching: adverse event reports for animal drugs. https://petdrugreports.com/reaction/retching/ Source: FDA Center for Veterinary Medicine, openFDA Animal and Veterinary adverse event reports, export of . Reports received through .

Where the data come from

The counts come from the openFDA Animal and Veterinary adverse event files, export of 30 Oct 2026. The files have the reports that the FDA Center for Veterinary Medicine received through 26 Jun 2026. The files mask brand and manufacturer names. The site counts a drug by the active ingredients that each record gives, and gives no count to a brand, an application or a company. Ingredient names and the lists of approved products follow the FDA Green Book of 2 Nov 2026. The site counts the different spellings of one VeDDRA term together.

The site does not publish report text, lot numbers or details of a reporter. FDA's record is the authority. See how the site counts reports, the data sources and the corrections page.

Questions about this sign

What does this term mean in a report?

It is a term from VeDDRA, the list of terms that FDA and drug companies use to code a report. The person who coded the report selected the term.

How does the count of the latest 12 months compare with the 12 months before?

FDA received 56 reports in the 12 months to June 2026. It received 81 reports in the 12 months before. FDA says that a report can take 3 to 6 months to reach the public data. The newest months can get more reports in a later update.

How many of these reports have a serious flag?

Of the 1,927 reports that say if the event was serious, 44.1% have the serious flag. The person who sends a report sets the flag.

Does a drug in the table cause this sign?

The reports do not show that. A report can name more than one drug. FDA states this about the data.

When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event.

The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources.

FDA Center for Veterinary Medicine. Source: Adverse Event Reports for Animal Drugs and Devices