Pet Drug Reports

Reported signs

Reported sign · VeDDRA term

Paddling: reports listing this term

1,324reports listing the term, 1987–20260.1% of all reports
78reports, 12 months to March 202673 in the 12 months before
87.9%classed serious, as reportedall reports: 38.6%
78.3%of these reports concern dogscat 8.5%

"Paddling" is a coded term listed in 1,324 adverse event reports received by FDA, 0.1% of the database. Terms come from VeDDRA, the veterinary dictionary that FDA and drug companies use to code what a reporter describes.

78 reports listed it in the 12 months to March 2026, close to the 73 of the 12 months before. FDA posts reports quarterly with a delay of three to six months, so the newest months are incomplete and usually grow in later releases.

By active ingredient, the drugs named most often in those reports are fluralaner, afoxolaner and ivermectin + pyrantel pamoate. That order mostly follows how many reports each has overall; the table gives the term's share within each drug's own reports as well.

78.3% of the reports concern dogs, 8.5% of the reports concern cats and 4.8% of the reports concern horses. Of reports listing this term that state seriousness, 87.9% were classed as serious; 22.1% record a death or euthanasia among the outcomes.

Drugs named most often in these reports, by active ingredient

Active ingredients recorded for the drugReports listing the termShare of that drug's own reports
Fluralaner2240.3%
Afoxolaner1800.3%
Ivermectin + Pyrantel Pamoate1030.1%
Propofol791.7%
Butorphanol Tartrate530.7%
Tiletamine Hydrochloride + Zolazepam Hydrochloride441.4%
Alfaxalone424.2%
Maropitant380.2%
Ketamine Hydrochloride370.5%
Isoflurane360.7%
Carprofen340.1%
Milbemycin Oxime + Spinosad340%
Midazolam321.6%
Buprenorphine310.4%
Ivermectin290.1%
Afoxolaner + Moxidectin + Pyrantel Pamoate260.3%
Pyrantel Pamoate + Sarolaner260%
Bedinvetmab230.1%
Moxidectin210%
Acepromazine Maleate200.8%
Oclacitinib200.1%
Selamectin200%
Milbemycin Oxime170.1%
Gabapentin160.2%
Hydromorphone161.2%

Ordered by number of reports, which mostly tracks how many reports a drug has overall. Across the whole database the term appears in 0.1% of reports. A drug's presence in a report means the animal received it, not that it produced the sign; FDA states that these data cannot be used to compare one product with another. openFDA masks brand and manufacturer names in adverse event records, so the reports counted here cannot be attributed to a particular brand.

Single ingredients, pooled across combinations

Active ingredientReports listing the termShare of the ingredient's own reports
Fluralaner2270.3%
Afoxolaner2060.3%
Pyrantel Pamoate1720.1%
Ivermectin1420.1%
Milbemycin Oxime810%
Propofol791.7%
Moxidectin630.1%
Butorphanol Tartrate540.7%
Tiletamine Hydrochloride511.3%
Spinosad480%
Sarolaner470.1%
Praziquantel460.1%
Zolazepam Hydrochloride441.4%
Alfaxalone424.2%
Ketamine Hydrochloride390.5%
Maropitant380.2%
Isoflurane360.7%
Carprofen340.1%
Midazolam321.6%
Buprenorphine310.4%
Selamectin240%
Bedinvetmab230.1%
Lufenuron220.1%
Acepromazine Maleate200.8%
Oclacitinib200.1%

Species split

Dog78.3%1,037
Cat8.5%112
Horse4.8%64
Cattle4.2%56
Pig2.4%32
Turkey0.5%7

Coloured bar: share of reports listing this term. Grey bar: the species' share of all reports. The term appears in 0.1% of all dog reports; The term appears in 0.1% of all cat reports.

Trend

0815Apr 2021: 10May 2021: 9Jun 2021: 7Jul 2021: 11Aug 2021: 9Sep 2021: 4Oct 2021: 5Nov 2021: 3Dec 2021: 1Jan 2022: 52022Feb 2022: 6Mar 2022: 7Apr 2022: 7May 2022: 5Jun 2022: 5Jul 2022: 7Aug 2022: 5Sep 2022: 7Oct 2022: 8Nov 2022: 4Dec 2022: 5Jan 2023: 42023Feb 2023: 6Mar 2023: 4Apr 2023: 7May 2023: 11Jun 2023: 7Jul 2023: 10Aug 2023: 10Sep 2023: 8Oct 2023: 6Nov 2023: 4Dec 2023: 6Jan 2024: 92024Feb 2024: 3Mar 2024: 5Apr 2024: 5May 2024: 10Jun 2024: 8Jul 2024: 4Aug 2024: 3Sep 2024: 4Oct 2024: 6Nov 2024: 3Dec 2024: 15Jan 2025: 52025Feb 2025: 5Mar 2025: 5Apr 2025: 8May 2025: 7Jun 2025: 12Jul 2025: 7Aug 2025: 14Sep 2025: 5Oct 2025: 8Nov 2025: 8Dec 2025: 4Jan 2026: 12026Feb 2026: 1Mar 2026: 3

Reports by month FDA received them, five years to March 2026. The newest months are incomplete because FDA posts reports with a delay of three to six months.

0511021987: 419871988: 61989: 131990: 61991: 619911992: 51993: 71994: 51995: 719951996: 51997: 41998: 161999: 1019992000: 182001: 102002: 122003: 1720032004: 222005: 222006: 422007: 2420072008: 222009: 282010: 412011: 1920112012: 512013: 322014: 392015: 4720152016: 432017: 562018: 1022019: 9720192020: 922021: 722022: 712023: 8320232024: 752025: 882026: 5

Outcomes and ages in these reports

Outcome recorded in the report

Recovered/Normal29.5%391
Recovered with Sequela1.7%22
Ongoing14.9%197
Died16.6%220
Euthanized5.5%73
Outcome Unknown13.4%178

Age of the animal

Under 1 year15%199
1 to 3 years23.2%307
4 to 7 years21.6%286
8 to 11 years17.4%231
12 years and over15.1%200
Age not given7.6%101
MeasureReports listing this termAll reports
Reports1,3241,357,245
Classed serious, of reports stating it87.9%38.6%
Death or euthanasia recorded, per 1,000 reports221.363.8

Grey bars and the right-hand column are the whole database. Outcomes are as stated by the reporter and describe the report as a whole, not this term alone.

Questions about "Paddling"

What does "Paddling" mean in an adverse event report?

It is a VeDDRA dictionary term picked to code what the reporter described. The report's free-text description is not published by FDA and is not shown here.

How many reports list paddling?

1,324 reports through March 2026 (0.1% of all reports), 78 of them in the latest 12 months.

Which drugs are named most often alongside this term?

By active ingredient: fluralaner (224), afoxolaner (180), ivermectin + pyrantel pamoate (103), propofol (79) and butorphanol tartrate (53). Drugs with many reports overall lead almost every term's list. Brands cannot be identified: openFDA masks them.

Which species are involved?

dog (78.3%), cat (8.5%), horse (4.8%) and cattle (4.2%).

Does a drug appearing here mean it produced this sign?

No such conclusion can be drawn. FDA states that "there is no certainty that the reported drug or device caused the adverse event" and that the event "may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources."

My animal shows this sign. What now?

This site cannot assess an animal. A veterinarian can; for an emergency, contact a veterinary emergency clinic. See the guide on when to call a vet.

Where this comes from. Counts are built from the openFDA Animal & Veterinary adverse event bulk files released 28 Sep 2026, which hold reports FDA's Center for Veterinary Medicine received through 31 Mar 2026. openFDA masks brand and manufacturer names in these files, so drugs are counted by the active ingredients each record discloses and no figure is attributed to a brand, application or company. Ingredient names, and the separate reference lists of approved products, follow the FDA Green Book as of 1 Oct 2026. Spelling variants of the same VeDDRA term (for example with and without a cross-reference note) are pooled. No report text, lot numbers or reporter details are published. See the methodology and sources; FDA's record is authoritative, and corrections are handled within five working days.