Pet Drug Reports

Apnoeain adverse event reports for animal drugs

Clinical sign, a VeDDRA term

In plain words: breathing stopped.

Read this first. FDA says this about the data:

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another. When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event. This dataset should not be the sole source of information for clinical decision-making or other assumptions about the safety or effectiveness of a product. The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources.

FDA Center for Veterinary Medicine publishes these words. Source: Adverse Event Reports for Animal Drugs and Devices, read on . The data have the reports that FDA received through .

This page is not veterinary advice. For an animal that is ill, speak to a veterinarian.

Contacting a veterinarianHow to report to FDA

From January 1987 to June 2026, FDA received 2,670 adverse event reports for animal drugs that list this sign. That is 0.2% of the 1,378,761 reports that FDA received from January 1987 to June 2026. In the 12 months to June 2026, FDA received 50 reports that list this sign.

Of the 2,670 reports, 59.4% are about dogs. A report can list more than one sign and more than one drug. A report is not proof that a drug caused a sign.

By number of reports in all years, this sign is number 221 of 1,149 clinical signs with a page. Reports that list this sign fell by 9.1% in the 12 months to June 2026, compared with the 12 months before. Reports for all animal drugs fell by 4.6% in the same periods. The newest months can get more reports in a later update. Reports about cats are 34% of the reports that list this sign, and 11% of all reports.

Search engines list a sign page with 3,000 reports or more in all years. The page also needs 300 reports or more in the 12 months to June 2026. This page is under one of these numbers. The site keeps the page and keeps it out of search engines.

Drug pages with reports that list this sign

The table has every drug page with 20 or more reports that list this sign, in order of name. No count decides which drug is in the table. The table has 30 drug pages.

Show the 30 drug pages
Drug pages with 20 or more reports that list this sign, in order of name
Active ingredientsReports that list the sign
Acepromazine Maleate80
Alfaxalone49
Amoxicillin23
Atipamezole Hydrochloride113
Atropine22
Buprenorphine34
Butorphanol Tartrate215
Carprofen140
Cefovecin sodium44
Deracoxib39
Dexmedetomidine54
Dexmedetomidine hydrochloride211
Fluralaner24
Gabapentin23
Hydromorphone37
Isoflurane244
Ivermectin20
Ketamine Hydrochloride385
Maropitant56
Medetomidine159
Melarsomine Dihydrochloride25
Meloxicam40
Midazolam50
Moxidectin46
Propofol294
Selamectin28
Sevoflurane175
Tiletamine Hydrochloride24
Tiletamine Hydrochloride + Zolazepam Hydrochloride259
Xylazine34

The openFDA records give the value "MSK" for the brand name and for the manufacturer name of each drug. FDA says that MSK means "masked". So the site cannot count a report for a brand. A report can name more than one drug.

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another.

The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources.

FDA Center for Veterinary Medicine. Source: Adverse Event Reports for Animal Drugs and Devices

Ingredients, all combinations

The list has every active ingredient with 20 or more reports that list this sign, in order of name. It has 33 ingredients.

Show the 33 ingredients

Reports by species

The share is of the 2,670 reports that list this sign. The sign is in 0.2% of all reports about the species dog. The sign is in 0.6% of all reports about the species cat.

Reports by month and by year

Reports for each month, Jul 2021 to Jun 2026. The month is the month in which FDA received the report.

FDA says that a report can take 3 to 6 months to reach the public data. The newest months can get more reports in a later update.

Reports that list Apnoea, by the year in which FDA received them
YearReports
202624
202552
202456
202340
202239
202155
202034
201944
201831
201731
201640
201536
201443
201352
201293
2011138
2010210
2009171
2008159
2007134
2006140
2005107
2004142
2003102
200299
200190
200089
199959
199864
199760
199625
199529
199414
199332
199236
199122
199030
198924
198812
198712

What these reports record

Outcome at the time of the report

  • Reports with this sign
  • All reports
  • Recovered/Normal9.1%243
  • Recovered with Sequela[recovered, with a lasting effect]0.1%3
  • Ongoing1.8%48
  • Died64.1%1,711
  • Euthanized1.4%38
  • Outcome Unknown0.9%23

An outcome in a report is not proof that the drug caused it. The person who sends the report gives the outcome. Each share is of the 2,670 reports that list this sign.

Age of the animal

  • Reports with this sign
  • All reports
  • Under 1 year24%641
  • 1 to 3 years19.6%523
  • 4 to 7 years18.7%500
  • 8 to 11 years14.2%378
  • 12 years and over6.6%175
  • Age not given17%453

The outcome is for the full report, not for this sign only.

Next in the A to Z list of signs

All clinical signs

Cite this page

Pet Drug Reports. Apnoea: adverse event reports for animal drugs. https://petdrugreports.com/reaction/apnoea/ Source: FDA Center for Veterinary Medicine, openFDA Animal and Veterinary adverse event reports, export of . Reports received through .

Where the data come from

The counts come from the openFDA Animal and Veterinary adverse event files, export of 30 Oct 2026. The files have the reports that the FDA Center for Veterinary Medicine received through 26 Jun 2026. The files mask brand and manufacturer names. The site counts a drug by the active ingredients that each record gives, and gives no count to a brand, an application or a company. Ingredient names and the lists of approved products follow the FDA Green Book of 2 Nov 2026. The site counts the different spellings of one VeDDRA term together.

The site does not publish report text, lot numbers or details of a reporter. FDA's record is the authority. See how the site counts reports, the data sources and the corrections page.

Questions about this sign

What does this term mean in a report?

In plain words: breathing stopped. It is a term from VeDDRA, the list of terms that FDA and drug companies use to code a report. The person who coded the report selected the term.

How does the count of the latest 12 months compare with the 12 months before?

FDA received 50 reports in the 12 months to June 2026. It received 55 reports in the 12 months before. FDA says that a report can take 3 to 6 months to reach the public data. The newest months can get more reports in a later update.

How many of these reports have a serious flag?

Of the 531 reports that say if the event was serious, 95.3% have the serious flag. The person who sends a report sets the flag.

Does a drug in the table cause this sign?

The reports do not show that. A report can name more than one drug. FDA states this about the data.

When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event.

The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources.

FDA Center for Veterinary Medicine. Source: Adverse Event Reports for Animal Drugs and Devices