Pet Drug Reports

Reported signs

Reported sign · VeDDRA term

Squinting: reports listing this term

873reports listing the term, 1989–20260.1% of all reports
78reports, 12 months to March 202673 in the 12 months before
52.7%classed serious, as reportedall reports: 38.6%
68.2%of these reports concern dogscat 30.8%

873 reports in FDA's animal adverse event database list the term "Squinting": 0.1% of all reports. It is a VeDDRA term, chosen by the person who coded the report to match what was described.

78 reports listed it in the 12 months to March 2026, close to the 73 of the 12 months before. FDA posts reports quarterly with a delay of three to six months, so the newest months are incomplete and usually grow in later releases.

By active ingredient, the drugs named most often in those reports are florfenicol + mometasone furoate + terbinafine, milbemycin oxime + spinosad and imidacloprid + moxidectin. That order mostly follows how many reports each has overall; the table gives the term's share within each drug's own reports as well.

68.2% of the reports concern dogs, 30.8% of the reports concern cats and 0.8% of the reports concern cattle. Of reports listing this term that state seriousness, 52.7% were classed as serious; 3.4% record a death or euthanasia among the outcomes.

Drugs named most often in these reports, by active ingredient

Active ingredients recorded for the drugReports listing the termShare of that drug's own reports
Florfenicol + Mometasone furoate + Terbinafine1793.3%
Milbemycin Oxime + Spinosad860.1%
Imidacloprid + Moxidectin570.2%
Maropitant520.3%
Cyclosporine490.2%
Spinosad460.1%
Fluralaner420%
Oclacitinib380.1%
Gabapentin320.3%
Selamectin320.1%
Prednisone310.3%
Bacitracin307.2%
Carprofen300.1%
Ketoconazole281.2%
Sarolaner + Selamectin280.3%
Cefovecin sodium260.2%
Afoxolaner240%
Ivermectin + Pyrantel Pamoate220%
Dexamethasone210.7%
Meloxicam200.1%
Enrofloxacin190.2%
Milbemycin Oxime + Praziquantel190.1%
Florfenicol + Terbinafine170.7%
Insulin170.1%
Moxidectin170%

Ordered by number of reports, which mostly tracks how many reports a drug has overall. Across the whole database the term appears in 0.1% of reports. A drug's presence in a report means the animal received it, not that it produced the sign; FDA states that these data cannot be used to compare one product with another. openFDA masks brand and manufacturer names in adverse event records, so the reports counted here cannot be attributed to a particular brand.

Single ingredients, pooled across combinations

Active ingredientReports listing the termShare of the ingredient's own reports
Florfenicol2122.1%
Terbinafine2122.5%
Mometasone furoate1803.1%
Spinosad1320.1%
Milbemycin Oxime1120%
Moxidectin870.1%
Imidacloprid620.2%
Selamectin600.1%
Pyrantel Pamoate570%
Praziquantel540.1%
Maropitant520.3%
Sarolaner500.1%
Cyclosporine490.2%
Fluralaner490.1%
Ivermectin400%
Oclacitinib380.1%
Dexamethasone340.7%
Gabapentin330.3%
Ketoconazole311.2%
Prednisone310.3%
Bacitracin306.2%
Carprofen300.1%
Afoxolaner280%
Cefovecin sodium260.2%
Enrofloxacin220.2%

Species split

Dog68.2%595
Cat30.8%269
Cattle0.8%7
Horse0.1%1
Human exposure0.1%1

Coloured bar: share of reports listing this term. Grey bar: the species' share of all reports. The term appears in 0.1% of all dog reports; The term appears in 0.2% of all cat reports.

Trend

0714Apr 2021: 3May 2021: 3Jun 2021: 6Jul 2021: 1Aug 2021: 10Sep 2021: 5Oct 2021: 10Nov 2021: 6Dec 2021: 3Jan 2022: 32022Feb 2022: 7Mar 2022: 3Apr 2022: 4May 2022: 7Jun 2022: 6Jul 2022: 8Aug 2022: 7Sep 2022: 5Oct 2022: 4Nov 2022: 9Dec 2022: 5Jan 2023: 52023Feb 2023: 4Mar 2023: 11Apr 2023: 10May 2023: 13Jun 2023: 6Jul 2023: 7Aug 2023: 10Sep 2023: 10Oct 2023: 14Nov 2023: 3Dec 2023: 5Jan 2024: 32024Feb 2024: 3Mar 2024: 11Apr 2024: 6May 2024: 5Jun 2024: 6Jul 2024: 9Aug 2024: 7Sep 2024: 12Oct 2024: 3Nov 2024: 6Dec 2024: 3Jan 2025: 92025Feb 2025: 5Mar 2025: 2Apr 2025: 10May 2025: 9Jun 2025: 3Jul 2025: 4Aug 2025: 9Sep 2025: 5Oct 2025: 8Nov 2025: 5Dec 2025: 9Jan 2026: 52026Feb 2026: 6Mar 2026: 5

Reports by month FDA received them, five years to March 2026. The newest months are incomplete because FDA posts reports with a delay of three to six months.

049981989: 119891994: 11995: 11997: 119971998: 11999: 12000: 320002001: 22004: 62005: 220052006: 32007: 42008: 820082009: 132010: 252011: 1320112012: 102013: 32014: 3320142015: 412016: 592017: 5720172018: 622019: 572020: 6820202021: 642022: 682023: 9820232024: 742025: 782026: 162026

Outcomes and ages in these reports

Outcome recorded in the report

Recovered/Normal23.7%207
Recovered with Sequela1.5%13
Ongoing33.3%291
Died1.9%17
Euthanized1.5%13
Outcome Unknown28.1%245

Age of the animal

Under 1 year12.7%111
1 to 3 years27.8%243
4 to 7 years27.1%237
8 to 11 years18.9%165
12 years and over9.7%85
Age not given3.7%32
MeasureReports listing this termAll reports
Reports8731,357,245
Classed serious, of reports stating it52.7%38.6%
Death or euthanasia recorded, per 1,000 reports34.463.8

Grey bars and the right-hand column are the whole database. Outcomes are as stated by the reporter and describe the report as a whole, not this term alone.

Questions about "Squinting"

What does "Squinting" mean in an adverse event report?

It is a VeDDRA dictionary term picked to code what the reporter described. The report's free-text description is not published by FDA and is not shown here.

How many reports list squinting?

873 reports through March 2026 (0.1% of all reports), 78 of them in the latest 12 months.

Which drugs are named most often alongside this term?

By active ingredient: florfenicol + mometasone furoate + terbinafine (179), milbemycin oxime + spinosad (86), imidacloprid + moxidectin (57), maropitant (52) and cyclosporine (49). Drugs with many reports overall lead almost every term's list. Brands cannot be identified: openFDA masks them.

Which species are involved?

dog (68.2%), cat (30.8%), cattle (0.8%) and horse (0.1%).

Does a drug appearing here mean it produced this sign?

No such conclusion can be drawn. FDA states that "there is no certainty that the reported drug or device caused the adverse event" and that the event "may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources."

My animal shows this sign. What now?

This site cannot assess an animal. A veterinarian can; for an emergency, contact a veterinary emergency clinic. See the guide on when to call a vet.

Where this comes from. Counts are built from the openFDA Animal & Veterinary adverse event bulk files released 28 Sep 2026, which hold reports FDA's Center for Veterinary Medicine received through 31 Mar 2026. openFDA masks brand and manufacturer names in these files, so drugs are counted by the active ingredients each record discloses and no figure is attributed to a brand, application or company. Ingredient names, and the separate reference lists of approved products, follow the FDA Green Book as of 1 Oct 2026. Spelling variants of the same VeDDRA term (for example with and without a cross-reference note) are pooled. No report text, lot numbers or reporter details are published. See the methodology and sources; FDA's record is authoritative, and corrections are handled within five working days.