April 2002: adverse event reports received

1,020 reports in the openFDA release of 28 Sep 2026

Read this first · FDA's caveat, in its words

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another. When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event. This dataset should not be the sole source of information for clinical decision-making or other assumptions about the safety or effectiveness of a product. The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources. FDA Center for Veterinary Medicine

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Not veterinary advice. This site lists what was reported to FDA. For an animal that is unwell, contact a veterinarian.

1,020reports received

1,272same month a year earlier-20%

1,202monthly average, preceding 12 months

65.8%concern dogscats 8.9%

FDA's database holds 1,020 adverse event reports received in April 2002, against 1,272 in the same month a year earlier and a monthly average of 1,202 over the preceding 12 months.

65.8% of the month's reports concern dogs, 8.9% cats and 2.3% horses; the rest concern other species, exposed people, or give no species.

By active ingredient, the drugs named most often were moxidectin (243), selamectin (152) and carprofen (117), and the terms listed most often were vomiting (168), anaphylaxis (116) and depression (112). Report volume has a seasonal shape, with more reports in the warmer months when parasite products are in heavier use.

The months around it

Drugs named most often, by active ingredient

Active ingredients recorded for the drug	Reports	Share of the month's reports
Moxidectin	243	23.8%
Selamectin	152	14.9%
Carprofen	117	11.5%
Ivermectin + Pyrantel Pamoate	42	4.1%
Ivermectin	41	4%
Milbemycin Oxime	36	3.5%
(S) - methoprene	32	3.1%
Melarsomine Dihydrochloride	29	2.8%
Tilmicosin Phosphate	27	2.6%
Butorphanol Tartrate	21	2.1%
Amoxicillin	19	1.9%
Etodolac	19	1.9%
Lufenuron + Milbemycin Oxime	18	1.8%
Enrofloxacin	14	1.4%
Doramectin	12	1.2%

Ordered by report count, which follows how widely each drug was in use. FDA states that these data cannot be used to estimate risk or to compare one product with another. Brand and manufacturer names are masked by FDA in these records.

Signs listed most often

Vomiting16.5%168
Anaphylaxis[sudden severe allergic-type reaction]11.4%116
Depression[dull, quiet or withdrawn]11%112
Accidental exposure[exposure that was not intended]10.6%108
Ineffective, heartworm larvae[legacy FDA term: the product did not have the expected effect (heartworm larvae)]10.6%108
Death8.3%85
Anorexia[not eating]8%82
Diarrhoea[diarrhea]7.5%76
Unclassifiable adverse event[event that fits no dictionary term]7.4%75
Facial oedema[swollen face]5.6%57
Urticaria[hives]5.5%56
Death by euthanasia[the animal was euthanized]4.6%47
Convulsion[seizure]4.4%45
No sign[no clinical sign was reported]4.2%43
Ataxia[unsteady, uncoordinated movement]3.7%38

Single ingredients, pooled

Moxidectin23.8%243

Selamectin14.9%152

Carprofen11.5%117

Ivermectin8.3%85

Milbemycin Oxime5.3%54

Pyrantel Pamoate4.5%46

(S) - methoprene3.1%32

Melarsomine Dihydrochloride2.8%29

Tilmicosin Phosphate2.6%27

Lufenuron2.5%25

Butorphanol Tartrate2.1%21

Amoxicillin1.9%19

Species

Dog65.8%671

Cat8.9%91

Horse2.3%23

Other or not given23%235

Questions about April 2002

How many animal drug adverse event reports did FDA receive in April 2002?

1,020 reports are in the openFDA release of 28 Sep 2026. The same month a year earlier has 1,272.

Which drugs were named most often?

By active ingredient: moxidectin (243), selamectin (152), carprofen (117), ivermectin + pyrantel pamoate (42) and ivermectin (41). Brands are masked in the public data.

Which signs were listed most often?

vomiting (168), anaphylaxis (116), depression (112), accidental exposure (108) and ineffective, heartworm larvae (108).

Can the count for a month still change?

Yes. FDA posts reports quarterly with a delay of three to six months, so the newest months are incomplete and usually grow in later releases. Older months change little.

Does a busy month mean something went wrong that month?

Not by itself. The date is when FDA received the report, not when the event happened, and volume follows season, product launches and publicity. FDA states that "there is no certainty that the reported drug or device caused the adverse event" and that the event "may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources."

Where this comes from. Counts are built from the openFDA Animal & Veterinary adverse event bulk files released 28 Sep 2026, which hold reports FDA's Center for Veterinary Medicine received through 31 Mar 2026. openFDA masks brand and manufacturer names in these files, so drugs are counted by the active ingredients each record discloses and no figure is attributed to a brand, application or company. Ingredient names, and the separate reference lists of approved products, follow the FDA Green Book as of 1 Oct 2026. The month is the date FDA first received the report, not the date of the event. No report text, lot numbers or reporter details are published. See the methodology and sources; FDA's record is authoritative, and corrections are handled within five working days.