Pet Drug Reports

Border Collie: adverse event reports for animal drugs

Breed of dog

The FDA breed label is "Collie - Border". The count has only the reports that give this one breed.

Read this first. FDA says this about the data:

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another. When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event. This dataset should not be the sole source of information for clinical decision-making or other assumptions about the safety or effectiveness of a product. The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources.

FDA Center for Veterinary Medicine publishes these words. Source: Adverse Event Reports for Animal Drugs and Devices, read on . The data have the reports that FDA received through .

This page is not veterinary advice. For an animal that is ill, speak to a veterinarian.

Contacting a veterinarianHow to report to FDA

From August 1987 to June 2026, FDA received 8,283 reports that give the breed Border Collie. That is 0.8% of the reports about dogs. In the 12 months to June 2026, FDA received 383 reports for this breed.

The count has only the reports that give this one breed. Reports about crossbred animals are in the count for the species. The signs that appear in the largest number of the 8,283 reports are "Vomiting", "Ineffective, heartworm larvae" and "Diarrhoea". A report is not proof that a drug caused a sign.

By number of reports in all years, this breed is number 21 of 167 breeds of dogs with a page. Reports that give this breed fell by 10.5% in the 12 months to June 2026, compared with the 12 months before. Reports about dogs fell by 2.3% in the same periods. The newest months can get more reports in a later update. The sign "Vomiting" is in 15.2% of the reports that give this breed, and in 19.6% of the reports about dogs.

Drug pages with reports for this breed

The table has every drug page with 5 or more reports that give this breed, in order of name. No count decides which drug is in the table. The table has 116 drug pages.

Show the 116 drug pages
Drug pages with 5 or more reports that give the breed Border Collie, in order of name
Active ingredientsReports that give this breed
(S) - methoprene44
Acepromazine Maleate11
Afoxolaner547
Afoxolaner + Moxidectin + Pyrantel Pamoate70
Alprazolam7
Amitraz10
Amitraz + (S) - methoprene10
Amoxicillin13
Amoxicillin Trihydrate + Clavulanate Potassium16
Atipamezole Hydrochloride17
Bedinvetmab240
Buprenorphine11
Butorphanol Tartrate29
Capromorelin7
Carprofen369
Cefovecin sodium8
Cefpodoxime proxetil21
Cephalexin16
Clindamycin7
Clomipramine Hydrochloride18
Clorsulon + Ivermectin6
Clotrimazole + Gentamicin Sulfate + Mometasone Furoate Monohydrate5
Cyclosporine50
Deracoxib105
Desoxycorticosterone Pivalate17
Dexamethasone12
Dexmedetomidine12
Dexmedetomidine hydrochloride37
Diphenhydramine16
Dirlotapide30
Doramectin8
Doxycycline35
Enalapril Maleate12
Enrofloxacin25
Eprinomectin19
Estriol25
Etodolac8
Famotidine15
Febantel + Praziquantel + Pyrantel Pamoate47
Fenbendazole31
Firocoxib90
Florfenicol + Mometasone furoate + Terbinafine7
Florfenicol + Terbinafine6
Fluoxetine hydrochloride23
Fluralaner589
Furosemide8
Gabapentin74
Gentamicin Sulfate + Hydrocortisone aceponate + Miconazole Nitrate6
Grapiprant104
Ilunocitinib7
Imidacloprid41
Imidacloprid + Moxidectin149
Insulin38
Isoflurane14
Ivermectin128
Ivermectin + Praziquantel5
Ivermectin + Praziquantel + Pyrantel Pamoate99
Ivermectin + Pyrantel Pamoate1,450
Ketamine Hydrochloride16
Ketoconazole6
Levetiracetam7
Levothyroxine sodium19
Lotilaner95
Lotilaner + Moxidectin + Praziquantel + Pyrantel Pamoate25
Lufenuron9
Lufenuron + Milbemycin Oxime344
Lufenuron + Milbemycin Oxime + Praziquantel67
Lufenuron + Praziquantel71
Marbofloxacin6
Maropitant73
Medetomidine17
Melarsomine Dihydrochloride183
Meloxicam70
Methocarbamol5
Metronidazole28
Midazolam7
Milbemycin Oxime383
Milbemycin Oxime + Praziquantel363
Milbemycin Oxime + Spinosad858
Moxidectin401
Moxidectin + Praziquantel10
Moxidectin + Pyrantel Pamoate + Sarolaner10
Nitenpyram63
Oclacitinib113
Ormetoprim + Sulfadimethoxine7
Oxibendazole11
Phenobarbital13
Phenylpropanolamine hydrochloride16
Pimobendan22
Polysulfated Glycosaminoglycan46
Praziquantel5
Praziquantel + Pyrantel Pamoate26
Prednisolone10
Prednisolone + Trimeprazine Tartrate9
Prednisone72
Propofol15
Pyrantel Pamoate24
Pyrantel Pamoate + Sarolaner421
Rabacfosadine10
Sarolaner136
Selamectin292
Selegiline Hydrochloride26
Spinosad228
Sucralfate10
Sulfadimethoxine8
Tepoxalin20
Tigilanol tiglate11
Tiletamine Hydrochloride + Zolazepam Hydrochloride6
Toceranib Phosphate9
Tramadol48
Trazodone17
Triamcinolone Acetonide5
Trilostane41
Trimethoprim5
Verdinexor11
Vitamin E5

The openFDA records give the value "MSK" for the brand name and for the manufacturer name of each drug. FDA says that MSK means "masked". So the site cannot count a report for a brand.

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another.

Commonly used products may have a higher number of reported adverse events due to the higher total number of animals being given the product.

FDA Center for Veterinary Medicine. Source: Adverse Event Reports for Animal Drugs and Devices

Signs that the reports list

A sign is a coded term from the report. The words in brackets are a plain gloss of the term. The percentage is the share of the 8,283 reports that list the sign.

The sign that is in the largest number of the reports comes first.

  1. Vomiting15.2%1,255 reports
  2. Ineffective, heartworm larvae[legacy FDA term: the product did not have the expected effect (heartworm larvae)]10.7%888 reports
  3. Diarrhoea[diarrhea]7.7%640 reports
  4. Lethargy[unusually tired or inactive]6.7%554 reports
  5. Lack of efficacy (endoparasite) - heartworm[the product did not have the expected effect: heartworm]6.3%520 reports
  6. Lack of efficacy (endoparasite) - hookworm[the product did not have the expected effect: hookworms]6.2%513 reports
  7. Lack of efficacy - NOS[the product did not have the expected effect]5.2%431 reports
  8. Anorexia[not eating]4.3%359 reports
  9. Seizure NOS[seizure, type not specified]4.1%337 reports
  10. Lack of efficacy (ectoparasite) - flea[the product did not have the expected effect: fleas]3.9%327 reports
  11. Emesis[vomiting]3.7%310 reports
  12. Ataxia[unsteady, uncoordinated movement]3.5%287 reports
  13. Depression[dull, quiet or withdrawn]3.1%258 reports
  14. Ineffective, ascarids NOS[legacy FDA term: the product did not have the expected effect (ascarids nos)]2.9%244 reports
Show the next 11 signs
  1. Death by euthanasia[the animal was euthanized]2.6%216 reports
  2. Elevated alanine aminotransferase (ALT)[a liver enzyme above the normal range]2.6%212 reports
  3. Death2.4%199 reports
  4. Digestive tract disorder NOS[digestive problem, type not specified]2.3%192 reports
  5. Elevated serum alkaline phosphatase (SAP)[a liver and bone enzyme above the normal range]2.2%180 reports
  6. Lack of efficacy (ectoparasite) - tick NOS[the product did not have the expected effect: ticks]2.1%174 reports
  7. Other abnormal test result NOS[abnormal laboratory result, type not specified]2.1%172 reports
  8. Behavioural disorder NOS[behaviour change, type not specified]2%164 reports
  9. Accidental exposure[exposure that was not intended]1.9%154 reports
  10. Lack of efficacy (endoparasite) - whipworm[the product did not have the expected effect: whipworms]1.8%145 reports
  11. Pruritus[itching]1.8%145 reports

What the reports record

Age of the animal

  • Border Collie reports
  • All reports about dogs
  • Under 1 year10.1%840, All reports about dogs: 10.3%
  • 1 to 3 years28.1%2,330, All reports about dogs: 29.2%
  • 4 to 7 years25%2,072, All reports about dogs: 24.5%
  • 8 to 11 years19.9%1,646, All reports about dogs: 18.4%
  • 12 years and over13.8%1,146, All reports about dogs: 10.1%
  • Age not given3%249, All reports about dogs: 7.6%

Weight of the animal

  • Border Collie reports
  • All reports about dogs
  • Under 5 kg (11 lb)1.4%114, All reports about dogs: 11.6%
  • 5 to 9.9 kg (11 to 22 lb)2.5%208, All reports about dogs: 18.7%
  • 10 to 24.9 kg (22 to 55 lb)68.9%5,708, All reports about dogs: 27.5%
  • 25 to 44.9 kg (55 to 99 lb)22.5%1,866, All reports about dogs: 30.4%
  • 45 kg and over (99 lb and over)0.3%24, All reports about dogs: 3.9%
  • Weight not given4.4%363, All reports about dogs: 7.9%

Outcome at the time of the report

  • Recovered/Normal20.6%1,704
  • Recovered with Sequela[recovered, with a lasting effect]3.6%296
  • Ongoing20.7%1,711
  • Died3.6%296
  • Euthanized1.7%137
  • Outcome Unknown27.6%2,286

An outcome in a report is not proof that the drug caused it. The person who sends the report gives the outcome. Each share is of the 8,283 reports that give this breed.

Each share of age and weight is of the 8,283 reports that give this breed. The thin bar is the same share in the 1,001,350 reports about dogs.

Reports by month and by year

Reports for each month, Jul 2021 to Jun 2026. The month is the month in which FDA received the report.

FDA says that a report can take 3 to 6 months to reach the public data. The newest months can get more reports in a later update.

Reports that give the breed Border Collie, by the year in which FDA received them
YearReports
2026190
2025413
2024458
2023372
2022333
2021373
2020420
2019495
2018480
2017524
2016483
2015511
2014418
2013390
2012362
2011268
2010252
2009275
2008255
2007196
2006137
2005147
2004118
200370
200272
200155
200090
199942
199835
199713
199610
19954
19943
19933
19922
19913
19901
19894
19885
19871

Next in the A to Z list of breeds

All reports about dogs. All breeds

Cite this page

Pet Drug Reports. Border Collie: adverse event reports for animal drugs. https://petdrugreports.com/breed/dog/border-collie/ Source: FDA Center for Veterinary Medicine, openFDA Animal and Veterinary adverse event reports, export of . Reports received through .

Where the data come from

The counts come from the openFDA Animal and Veterinary adverse event files, export of 30 Oct 2026. The files have the reports that the FDA Center for Veterinary Medicine received through 26 Jun 2026. The files mask brand and manufacturer names. The site counts a drug by the active ingredients that each record gives, and gives no count to a brand, an application or a company. Ingredient names and the lists of approved products follow the FDA Green Book of 2 Nov 2026. The site puts the FDA breed label in the usual order of the words.

The site does not publish report text, lot numbers or details of a reporter. FDA's record is the authority. See how the site counts reports, the data sources and the corrections page.

Questions about these reports

What ages are the animals in the reports?

The figures are shares of the 8,283 reports about this breed received from August 1987 to June 2026. 28.1% give an age of 1 to 3 years. 25% give an age of 4 to 7 years. 3% give no age.

How does the count of the latest 12 months compare with the 12 months before?

FDA received 383 reports in the 12 months to June 2026. It received 428 reports in the 12 months before. FDA says that a report can take 3 to 6 months to reach the public data. The newest months can get more reports in a later update.

Why are crossbred animals not in the count?

The site counts a report for a breed only when the report gives one breed. A report for a crossbred animal can give more than one breed, and a count for each breed would count the report more than once. The reports about crossbred animals are in the count for dogs.

Do the reports show that this breed reacts more to a drug?

No. The reports do not give the number of animals of the breed. FDA states this about the data.

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another.

FDA Center for Veterinary Medicine. Source: Adverse Event Reports for Animal Drugs and Devices