Wheezing: in adverse event reports for animal drugs

Clinical sign, a VeDDRA term

Read this first. FDA says this about the data:

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another. When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event. This dataset should not be the sole source of information for clinical decision-making or other assumptions about the safety or effectiveness of a product. The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources.
FDA Center for Veterinary Medicine publishes these words. Source: Adverse Event Reports for Animal Drugs and Devices, read on 2 Oct 2026. The data have the reports that FDA received through 26 Jun 2026.

This page is not veterinary advice. For an animal that is ill, speak to a veterinarian.

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From January 1988 to June 2026, FDA received 1,107 adverse event reports for animal drugs that list this sign. That is under 0.1% of the 1,378,761 reports that FDA received from January 1987 to June 2026. In the 12 months to June 2026, FDA received 78 reports that list this sign.

Of the 1,107 reports, 69.7% are about dogs. A report can list more than one sign and more than one drug. A report is not proof that a drug caused a sign.

By number of reports in all years, this sign is number 451 of 1,149 clinical signs with a page. Reports that list this sign rose by 6.8% in the 12 months to June 2026, compared with the 12 months before. Reports for all animal drugs fell by 4.6% in the same periods. The newest months can get more reports in a later update. Reports about cats are 24.8% of the reports that list this sign, and 11% of all reports.

Search engines list a sign page with 3,000 reports or more in all years. The page also needs 300 reports or more in the 12 months to June 2026. This page is under one of these numbers. The site keeps the page and keeps it out of search engines.

Drug pages with reports that list this sign

The table has every drug page with 20 or more reports that list this sign, in order of name. No count decides which drug is in the table. The table has 25 drug pages.

Drug pages with 20 or more reports that list this sign, in order of name
Active ingredients	Reports that list the sign
Afoxolaner	43
Bedinvetmab	26
Butorphanol Tartrate	20
Carprofen	58
Cefovecin sodium	47
Cyclosporine	32
Doxycycline	20
Fluralaner	57
Frunevetmab	21
Furosemide	21
Gabapentin	22
Imidacloprid + Moxidectin	39
Ivermectin + Pyrantel Pamoate	56
Lufenuron + Milbemycin Oxime	20
Maropitant	61
Melarsomine Dihydrochloride	46
Meloxicam	27
Milbemycin Oxime + Spinosad	95
Moxidectin	65
Nitenpyram	21
Oclacitinib	32
Pimobendan	29
Prednisone	21
Selamectin	64
Spinosad	26

The openFDA records give the value "MSK" for the brand name and for the manufacturer name of each drug. FDA says that MSK means "masked". So the site cannot count a report for a brand. A report can name more than one drug.

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another.
The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources.
FDA Center for Veterinary Medicine. Source: Adverse Event Reports for Animal Drugs and Devices

Ingredients, all combinations

The list has every active ingredient with 20 or more reports that list this sign, in order of name. It has 30 ingredients.

Show the 30 ingredients

Reports by species

Dog69.7%772
Cat24.8%275
Human exposure2.5%28
Horse1.4%15
Cattle0.9%10
Pig0.2%2

The share is of the 1,107 reports that list this sign. The sign is in 0.1% of all reports about the species dog. The sign is in 0.2% of all reports about the species cat.

Reports by month and by year

Reports for each month, Jul 2021 to Jun 2026. The month is the month in which FDA received the report.

FDA says that a report can take 3 to 6 months to reach the public data. The newest months can get more reports in a later update.

Reports that list Wheezing, by the year in which FDA received them
Year	Reports
2026	37
2025	74
2024	81
2023	65
2022	41
2021	38
2020	40
2019	41
2018	57
2017	65
2016	59
2015	54
2014	56
2013	55
2012	69
2011	38
2010	34
2009	33
2008	35
2007	20
2006	20
2005	24
2004	21
2003	10
2002	13
2001	6
2000	7
1999	7
1998	4
1995	1
1990	1
1988	1

What these reports record

Outcome at the time of the report

Reports with this sign
All reports

Recovered/Normal17%188, All reports: 20.7%
Recovered with Sequela[recovered, with a lasting effect]2.4%27, All reports: 2.3%
Ongoing22%243, All reports: 17.4%
Died13.2%146, All reports: 4.9%
Euthanized6.1%67, All reports: 1.5%
Outcome Unknown20.1%223, All reports: 22.7%

An outcome in a report is not proof that the drug caused it. The person who sends the report gives the outcome. Each share is of the 1,107 reports that list this sign.

Age of the animal

Reports with this sign
All reports

Under 1 year9.8%108, All reports: 9.5%
1 to 3 years21.3%236, All reports: 23.9%
4 to 7 years22.9%253, All reports: 20.2%
8 to 11 years25.7%284, All reports: 15.4%
12 years and over17.8%197, All reports: 10.7%
Age not given2.6%29, All reports: 20.3%

The outcome is for the full report, not for this sign only.

Next in the A to Z list of signs

All clinical signs

Cite this page

Pet Drug Reports. Wheezing: adverse event reports for animal drugs. https://petdrugreports.com/reaction/wheezing/ Source: FDA Center for Veterinary Medicine, openFDA Animal and Veterinary adverse event reports, export of 30 Oct 2026. Reports received through 26 Jun 2026.

Where the data come from

The counts come from the openFDA Animal and Veterinary adverse event files, export of 30 Oct 2026. The files have the reports that the FDA Center for Veterinary Medicine received through 26 Jun 2026. The files mask brand and manufacturer names. The site counts a drug by the active ingredients that each record gives, and gives no count to a brand, an application or a company. Ingredient names and the lists of approved products follow the FDA Green Book of 2 Nov 2026. The site counts the different spellings of one VeDDRA term together.

The site does not publish report text, lot numbers or details of a reporter. FDA's record is the authority. See how the site counts reports, the data sources and the corrections page.

Questions about this sign

What does this term mean in a report?: It is a term from VeDDRA, the list of terms that FDA and drug companies use to code a report. The person who coded the report selected the term.
How does the count of the latest 12 months compare with the 12 months before?: FDA received 78 reports in the 12 months to June 2026. It received 73 reports in the 12 months before. FDA says that a report can take 3 to 6 months to reach the public data. The newest months can get more reports in a later update.
How many of these reports have a serious flag?: Of the 809 reports that say if the event was serious, 64.2% have the serious flag. The person who sends a report sets the flag.
Does a drug in the table cause this sign?: The reports do not show that. A report can name more than one drug. FDA states this about the data.
When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event.
The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources.
FDA Center for Veterinary Medicine. Source: Adverse Event Reports for Animal Drugs and Devices