Renal disorder NOS: in adverse event reports for animal drugs

Clinical sign, a VeDDRA term

In plain words: kidney disorder, type not specified.

Read this first. FDA says this about the data:

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another. When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event. This dataset should not be the sole source of information for clinical decision-making or other assumptions about the safety or effectiveness of a product. The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources.
FDA Center for Veterinary Medicine publishes these words. Source: Adverse Event Reports for Animal Drugs and Devices, read on 2 Oct 2026. The data have the reports that FDA received through 26 Jun 2026.

This page is not veterinary advice. For an animal that is ill, speak to a veterinarian.

Contacting a veterinarian How to report to FDA

From November 1988 to June 2026, FDA received 2,148 adverse event reports for animal drugs that list this sign. That is 0.2% of the 1,378,761 reports that FDA received from January 1987 to June 2026. In the 12 months to June 2026, FDA received 138 reports that list this sign.

Of the 2,148 reports, 71% are about dogs. A report can list more than one sign and more than one drug. A report is not proof that a drug caused a sign.

By number of reports in all years, this sign is number 261 of 1,149 clinical signs with a page. Reports that list this sign fell by 29.2% in the 12 months to June 2026, compared with the 12 months before. Reports for all animal drugs fell by 4.6% in the same periods. The newest months can get more reports in a later update. Reports about cats are 25.3% of the reports that list this sign, and 11% of all reports.

Search engines list a sign page with 3,000 reports or more in all years. The page also needs 300 reports or more in the 12 months to June 2026. This page is under one of these numbers. The site keeps the page and keeps it out of search engines.

Drug pages with reports that list this sign

The table has every drug page with 20 or more reports that list this sign, in order of name. No count decides which drug is in the table. The table has 44 drug pages.

Show the 44 drug pages

Drug pages with 20 or more reports that list this sign, in order of name
Active ingredients	Reports that list the sign
Afoxolaner	68
Amoxicillin	26
Amoxicillin + Clavulanate Potassium	21
Amoxicillin Trihydrate + Clavulanate Potassium	30
Bedinvetmab	89
Bexagliflozin	47
Buprenorphine	51
Butorphanol Tartrate	24
Capromorelin	30
Carprofen	305
Cefovecin sodium	122
Cyclosporine	39
Deracoxib	80
Diphenhydramine	21
Doxycycline	28
Enrofloxacin	53
Famotidine	47
Firocoxib	53
Fluralaner	118
Frunevetmab	42
Gabapentin	84
Grapiprant	48
Imidacloprid + Moxidectin	37
Isoflurane	22
Ivermectin	34
Ivermectin + Pyrantel Pamoate	55
Maropitant	149
Meloxicam	112
Metronidazole	30
Milbemycin Oxime	23
Milbemycin Oxime + Praziquantel	44
Milbemycin Oxime + Spinosad	149
Mirtazapine	30
Moxidectin	43
Oclacitinib	100
Polysulfated Glycosaminoglycan	27
Prednisone	45
Pyrantel Pamoate + Sarolaner	24
Robenacoxib	26
Sarolaner	21
Selamectin	61
Spinosad	78
Tramadol	43
Trilostane	59

The openFDA records give the value "MSK" for the brand name and for the manufacturer name of each drug. FDA says that MSK means "masked". So the site cannot count a report for a brand. A report can name more than one drug.

An API dataset query result cannot be used to estimate the risk associated with the product or compare one drug or device product with another.
The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources.
FDA Center for Veterinary Medicine. Source: Adverse Event Reports for Animal Drugs and Devices

Ingredients, all combinations

The list has every active ingredient with 20 or more reports that list this sign, in order of name. It has 46 ingredients.

Show the 46 ingredients

Reports by species

Dog71%1,526
Cat25.3%543
Horse1%22
Cattle0.9%20
Human exposure0.4%9
Chicken0.3%7

The share is of the 2,148 reports that list this sign. The sign is in 0.2% of all reports about the species dog. The sign is in 0.4% of all reports about the species cat.

Reports by month and by year

Reports for each month, Jul 2021 to Jun 2026. The month is the month in which FDA received the report.

FDA says that a report can take 3 to 6 months to reach the public data. The newest months can get more reports in a later update.

Reports that list Renal disorder NOS, by the year in which FDA received them
Year	Reports
2026	57
2025	168
2024	199
2023	84
2022	74
2021	75
2020	76
2019	94
2018	96
2017	114
2016	137
2015	108
2014	90
2013	113
2012	113
2011	65
2010	55
2009	56
2008	73
2007	52
2006	47
2005	23
2004	33
2003	15
2002	12
2001	27
2000	25
1999	20
1998	23
1997	8
1996	2
1995	5
1994	2
1993	1
1992	4
1990	1
1988	1

What these reports record

Outcome at the time of the report

Reports with this sign
All reports

Recovered/Normal4.1%87, All reports: 20.7%
Recovered with Sequela[recovered, with a lasting effect]2.4%51, All reports: 2.3%
Ongoing22.5%483, All reports: 17.4%
Died23.3%500, All reports: 4.9%
Euthanized17.2%369, All reports: 1.5%
Outcome Unknown16.2%347, All reports: 22.7%

An outcome in a report is not proof that the drug caused it. The person who sends the report gives the outcome. Each share is of the 2,148 reports that list this sign.

Age of the animal

Reports with this sign
All reports

Under 1 year6.6%142, All reports: 9.5%
1 to 3 years9.8%210, All reports: 23.9%
4 to 7 years17.7%380, All reports: 20.2%
8 to 11 years25.4%545, All reports: 15.4%
12 years and over33.4%718, All reports: 10.7%
Age not given7.1%153, All reports: 20.3%

The outcome is for the full report, not for this sign only.

Next in the A to Z list of signs

All clinical signs

Cite this page

Pet Drug Reports. Renal disorder NOS: adverse event reports for animal drugs. https://petdrugreports.com/reaction/renal-disorder-nos/ Source: FDA Center for Veterinary Medicine, openFDA Animal and Veterinary adverse event reports, export of 30 Oct 2026. Reports received through 26 Jun 2026.

Where the data come from

The counts come from the openFDA Animal and Veterinary adverse event files, export of 30 Oct 2026. The files have the reports that the FDA Center for Veterinary Medicine received through 26 Jun 2026. The files mask brand and manufacturer names. The site counts a drug by the active ingredients that each record gives, and gives no count to a brand, an application or a company. Ingredient names and the lists of approved products follow the FDA Green Book of 2 Nov 2026. The site counts the different spellings of one VeDDRA term together.

The site does not publish report text, lot numbers or details of a reporter. FDA's record is the authority. See how the site counts reports, the data sources and the corrections page.

Questions about this sign

What does this term mean in a report?: In plain words: kidney disorder, type not specified. It is a term from VeDDRA, the list of terms that FDA and drug companies use to code a report. The person who coded the report selected the term.
How does the count of the latest 12 months compare with the 12 months before?: FDA received 138 reports in the 12 months to June 2026. It received 195 reports in the 12 months before. FDA says that a report can take 3 to 6 months to reach the public data. The newest months can get more reports in a later update.
How many of these reports have a serious flag?: Of the 1,568 reports that say if the event was serious, 77.8% have the serious flag. The person who sends a report sets the flag.
Does a drug in the table cause this sign?: The reports do not show that. A report can name more than one drug. FDA states this about the data.
When looking at the results, be aware that there is no certainty that the reported drug or device caused the adverse event.
The adverse event may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources.
FDA Center for Veterinary Medicine. Source: Adverse Event Reports for Animal Drugs and Devices