Pet Drug Reports

Reported signs

Reported sign · VeDDRA term

Limb non-weight bearing: reports listing this term

508reports listing the term, 2017–20260% of all reports
139reports, 12 months to March 2026125 in the 12 months before
72.2%classed serious, as reportedall reports: 38.6%
91.3%of these reports concern dogscat 6.9%

508 reports in FDA's animal adverse event database list the term "Limb non-weight bearing": 0% of all reports. It is a VeDDRA term, chosen by the person who coded the report to match what was described.

139 reports listed it in the 12 months to March 2026, up 11% from 125 in the 12 months before. FDA posts reports quarterly with a delay of three to six months, so the newest months are incomplete and usually grow in later releases.

By active ingredient, the drugs named most often in those reports are tigilanol tiglate, bedinvetmab and gabapentin. That order mostly follows how many reports each has overall; the table gives the term's share within each drug's own reports as well.

91.3% of the reports concern dogs, 6.9% of the reports concern cats and 1.6% of the reports concern horses. Of reports listing this term that state seriousness, 72.2% were classed as serious; 16.1% record a death or euthanasia among the outcomes.

Drugs named most often in these reports, by active ingredient

Active ingredients recorded for the drugReports listing the termShare of that drug's own reports
Tigilanol tiglate1738.7%
Bedinvetmab1440.8%
Gabapentin750.7%
Butorphanol Tartrate600.8%
Carprofen450.1%
Prednisone440.5%
Diphenhydramine350.7%
Maropitant350.2%
Fluralaner320%
Dexmedetomidine311.2%
Famotidine311%
Grapiprant280.3%
Atipamezole Hydrochloride250.6%
Buprenorphine250.3%
Oclacitinib210.1%
Propofol170.4%
Dexmedetomidine hydrochloride140.2%
Polysulfated Glycosaminoglycan130.2%
Pyrantel Pamoate + Sarolaner130%
Amantadine122.4%
Frunevetmab120.2%
Trazodone110.7%
Lotilaner90.1%
Melarsomine Dihydrochloride90%
Afoxolaner80%

Ordered by number of reports, which mostly tracks how many reports a drug has overall. Across the whole database the term appears in 0% of reports. A drug's presence in a report means the animal received it, not that it produced the sign; FDA states that these data cannot be used to compare one product with another. openFDA masks brand and manufacturer names in adverse event records, so the reports counted here cannot be attributed to a particular brand.

Single ingredients, pooled across combinations

Active ingredientReports listing the termShare of the ingredient's own reports
Tigilanol tiglate1738.7%
Bedinvetmab1440.8%
Gabapentin750.7%
Butorphanol Tartrate640.8%
Carprofen450.1%
Prednisone440.5%
Diphenhydramine350.7%
Maropitant350.2%
Dexmedetomidine331.1%
Fluralaner330%
Famotidine311%
Pyrantel Pamoate290%
Grapiprant280.3%
Atipamezole Hydrochloride250.6%
Buprenorphine250.3%
Oclacitinib210.1%
Milbemycin Oxime190%
Praziquantel170%
Propofol170.4%
Sarolaner170%
Dexmedetomidine hydrochloride150.3%
Moxidectin140%
Polysulfated Glycosaminoglycan130.2%
Amantadine122.4%
Frunevetmab120.2%

Species split

Dog91.3%464
Cat6.9%35
Horse1.6%8
Alpaca0.2%1

Coloured bar: share of reports listing this term. Grey bar: the species' share of all reports. The term appears in 0% of all dog reports; The term appears in 0% of all cat reports.

Trend

0917Apr 2021: 4May 2021: 2Jun 2021: 4Jul 2021: 1Aug 2021: 4Sep 2021: 6Oct 2021: 8Nov 2021: 8Dec 2021: 7Jan 2022: 92022Feb 2022: 5Mar 2022: 6Apr 2022: 4May 2022: 5Jun 2022: 2Jul 2022: 1Aug 2022: 7Sep 2022: 3Oct 2022: 5Nov 2022: 4Dec 2022: 2Jan 2023: 112023Feb 2023: 6Mar 2023: 6Apr 2023: 6May 2023: 10Jun 2023: 6Jul 2023: 10Aug 2023: 11Sep 2023: 4Oct 2023: 11Nov 2023: 14Dec 2023: 7Jan 2024: 162024Feb 2024: 11Mar 2024: 11Apr 2024: 9May 2024: 13Jun 2024: 14Jul 2024: 8Aug 2024: 9Sep 2024: 8Oct 2024: 13Nov 2024: 7Dec 2024: 15Jan 2025: 102025Feb 2025: 11Mar 2025: 8Apr 2025: 14May 2025: 13Jun 2025: 13Jul 2025: 11Aug 2025: 17Sep 2025: 14Oct 2025: 9Nov 2025: 6Dec 2025: 14Jan 2026: 122026Feb 2026: 10Mar 2026: 6

Reports by month FDA received them, five years to March 2026. The newest months are incomplete because FDA posts reports with a delay of three to six months.

0701402017: 120172021: 5020212022: 5320222023: 10220232024: 13420242025: 14020252026: 282026

Outcomes and ages in these reports

Outcome recorded in the report

Recovered/Normal19.7%100
Recovered with Sequela1.6%8
Ongoing31.5%160
Died4.7%24
Euthanized11.4%58
Outcome Unknown31.1%158

Age of the animal

Under 1 year6.1%31
1 to 3 years5.3%27
4 to 7 years25%127
8 to 11 years38.6%196
12 years and over22%112
Age not given3%15
MeasureReports listing this termAll reports
Reports5081,357,245
Classed serious, of reports stating it72.2%38.6%
Death or euthanasia recorded, per 1,000 reports161.463.8

Grey bars and the right-hand column are the whole database. Outcomes are as stated by the reporter and describe the report as a whole, not this term alone.

Questions about "Limb non-weight bearing"

What does "Limb non-weight bearing" mean in an adverse event report?

It is a VeDDRA dictionary term picked to code what the reporter described. The report's free-text description is not published by FDA and is not shown here.

How many reports list limb non-weight bearing?

508 reports through March 2026 (0% of all reports), 139 of them in the latest 12 months.

Which drugs are named most often alongside this term?

By active ingredient: tigilanol tiglate (173), bedinvetmab (144), gabapentin (75), butorphanol tartrate (60) and carprofen (45). Drugs with many reports overall lead almost every term's list. Brands cannot be identified: openFDA masks them.

Which species are involved?

dog (91.3%), cat (6.9%), horse (1.6%) and alpaca (0.2%).

Does a drug appearing here mean it produced this sign?

No such conclusion can be drawn. FDA states that "there is no certainty that the reported drug or device caused the adverse event" and that the event "may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources."

My animal shows this sign. What now?

This site cannot assess an animal. A veterinarian can; for an emergency, contact a veterinary emergency clinic. See the guide on when to call a vet.

Where this comes from. Counts are built from the openFDA Animal & Veterinary adverse event bulk files released 28 Sep 2026, which hold reports FDA's Center for Veterinary Medicine received through 31 Mar 2026. openFDA masks brand and manufacturer names in these files, so drugs are counted by the active ingredients each record discloses and no figure is attributed to a brand, application or company. Ingredient names, and the separate reference lists of approved products, follow the FDA Green Book as of 1 Oct 2026. Spelling variants of the same VeDDRA term (for example with and without a cross-reference note) are pooled. No report text, lot numbers or reporter details are published. See the methodology and sources; FDA's record is authoritative, and corrections are handled within five working days.