Pet Drug Reports

Ingredients

Active ingredient · pooled across combinations

Bacitracin Zinc: adverse event reports, pooled

5 ingredient sets in reports · 56 FDA-approved applications in the Green Book

81reports naming the ingredient, 2011–20260% of all reports · about 6 a year
10reports, 12 months to March 20265 in the 12 months before
57.7%classed serious, as reportedall reports: 38.6%
82.7%of reports concern dogscat 13.6%

81 adverse event reports received by FDA list a drug containing bacitracin zinc, alone or in combination, from December 2011 to March 2026. This page pools every ingredient set that includes it; 5 such sets appear in reports.

The Green Book lists 56 FDA-approved applications containing it. openFDA masks brand and manufacturer names in adverse event records, so the reports counted here cannot be attributed to a particular brand.

10 reports arrived in the 12 months to March 2026, up 100% from 5 in the 12 months before. FDA posts reports quarterly with a delay of three to six months, so the newest months are incomplete and usually grow in later releases. That is about 6 reports a year over its reporting history and 0% of all reports.

Pooled across every set, the terms listed most often are corneal ulcer (19.8%), ocular discharge (17.3%) and vomiting (17.3%). Many drugs combine several ingredients, and many reports list several drugs, so a term on this page may relate to any of them or to none.

Of reports that state seriousness, 57.7% were classed as serious (38.6% across the whole database); 3.7% record a death or euthanasia (6.4% overall). Ingredients used in older or sicker animals, or in anaesthesia and cancer care, carry higher shares for that reason alone.

Ingredient sets that include bacitracin zinc

Active ingredients recorded for the drugReportsShare of this page's reportsLatest 12 months
Bacitracin Zinc4960.5%8
Bacitracin Zinc + Neomycin Sulfate + Polymyxin B Sulfate1721%2
Bacitracin Zinc + Polymyxin B Sulfate1316%0
Bacitracin Zinc + Hydrocortisone11.2%0
Bacitracin Zinc + Neomycin Sulfate11.2%0

Ordered by report count. FDA states that these data "cannot be used to estimate the risk associated with the product or compare one drug or device product with another"; counts follow sales volume and years on the market. A report can list more than one set, so shares can add to more than 100%.

Signs listed in reports, pooled

share of bacitracin zinc reports listing the termall reports in the database

  1. Vomiting17.3%14
  2. Diarrhoea[diarrhea]16%13
  3. Other abnormal test result NOS[abnormal laboratory result, type not specified]16%13
  4. Lethargy[unusually tired or inactive]13.6%11
  5. Corneal disorder NOS[NOS: not otherwise specified]9.9%8
  6. Lack of efficacy - NOS[the product did not have the expected effect]8.6%7
  7. Nystagmus[rapid involuntary eye movement]8.6%7
  8. Emesis[vomiting]7.4%6
  9. Ataxia[unsteady, uncoordinated movement]6.2%5
  10. Behavioural disorder NOS[behaviour change, type not specified]6.2%5
  11. Skin lesion NOS[NOS: not otherwise specified]6.2%5
  12. Cough4.9%4
  13. Ear infection NOS[NOS: not otherwise specified]4.9%4

Pooled across every ingredient set and every report that names the ingredient. One report can list several terms and several drugs; a term here may relate to any of them or to none.

Monthly reports by species, five years

Dog22 · peak 3
Jun 2021: 1Jul 2021: 1Aug 2022: 1Nov 2022: 1Dec 2022: 1May 2023: 1Aug 2023: 1Oct 2023: 1Sep 2024: 2Oct 2024: 1Jan 2025: 1May 2025: 3Aug 2025: 2Sep 2025: 1Oct 2025: 1Dec 2025: 1Mar 2026: 22022202320242025
Cat5 · peak 1
Apr 2021: 1Jun 2022: 1Dec 2022: 1Jun 2023: 1Sep 2024: 12022202320242025
Horse0 · peak 1
2022202320242025
Other3 · peak 2
Sep 2021: 1Oct 2021: 22022202320242025

By month of receipt; each panel has its own scale. The newest months are incomplete because FDA posts reports with a delay of three to six months.

06122011: 120112012: 320122013: 220132014: 320142015: 420152016: 1020162017: 520172018: 420182019: 320192020: 1020202021: 1220212022: 520222023: 420232024: 420242025: 920252026: 22026

Outcomes, report types and ages

Outcome recorded in the report

Recovered/Normal22.2%18
Recovered with Sequela1.2%1
Ongoing22.2%18
Died2.5%2
Euthanized1.2%1
Outcome Unknown46.9%38

What kind of report it was

Safety issue74.1%60
Lack of expected effectiveness7.4%6
Both safety and lack of expected effectiveness12.3%10
Manufacturing or product defect6.2%5
Other0%0

Species

Dog82.7%67
Cat13.6%11

Age of the animal

Under 1 year13.6%11
1 to 3 years21%17
4 to 7 years25.9%21
8 to 11 years21%17
12 years and over12.3%10
Age not given6.2%5

Coloured bar: reports naming bacitracin zinc. Grey bar: all 1,357,245 reports. Outcomes are as stated by the reporter; FDA has not necessarily determined whether any product played a part.

In context

MeasureBacitracin ZincAll reports
Reports811,357,245
Latest 12 months against the 12 before+100%-5%
Classed serious, of reports stating it57.7%38.6%
Death or euthanasia recorded, per 1,000 reports3763.8
Filed as lack of expected effectiveness (wholly or partly)19.8%23%

Shares of reports, not of animals treated: how many animals receive the ingredient is not public. Ingredients used in anaesthesia, cancer care or in old animals carry more serious outcomes in their reports for that reason alone.

FDA-approved products containing bacitracin zinc (Green Book)

Reference information, not report statistics. openFDA masks brand and manufacturer names in adverse event records, so the reports counted here cannot be attributed to a particular brand. The list below is the FDA Green Book as of 30 Sep 2026; nothing on this page says which of these products, if any, a report concerned.

Trade nameActive ingredientsSponsorApproved forApplication
Deccox and AlbacBacitracin Zinc, DecoquinatePhibro Animal Health Corp.ChickensNADA 045-348
Baciferm - 10; Baciferm - 25; Baciferm - 40; Baciferm - 50Bacitracin ZincZoetis Inc.Cattle, Swine, Chickens, TurkeysNADA 046-920
Coban plus BacifermBacitracin Zinc, MonensinElanco US Inc.ChickensNADA 047-933
Coyden 25 with Bacitracin ZincBacitracin Zinc, ClopidolHuvepharma EOODChickensNADA 049-934
Bacitracin-Neomycin-Polymyxin with Hydrocortisone Acetate Ophthalmic Ointment; Vetropolycin HC Ophthalmic OintmentBacitracin Zinc, Hydrocortisone Acetate, Neomycin Sulfate, Polymyxin B SulfateDechra Veterinary Products LLCDogs, CatsNADA 065-015
Bac-Neo-Poly Ophthalmic Ointment; Vetropolycin Ophthalmic OintmentBacitracin Zinc, Neomycin Sulfate, Polymyxin B SulfateDechra Veterinary Products LLCDogs, CatsNADA 065-016
Mycitracin Sterile Ophthalmic OintmentBacitracin Zinc, Neomycin Sulfate, Polymyxin B SulfateZoetis Inc.Dogs, CatsNADA 065-114
Baciferm Soluble 50Bacitracin ZincZoetis Inc.ChickensNADA 065-313
Cortisporin Veterinary Ophthalmic OintmentBacitracin Zinc, Hydrocortisone, Neomycin Sulfate, Polymyxin B SulfateIntervet, Inc.Dogs, CatsNADA 065-476
Neosporin Ophthalmic OintmentBacitracin Zinc, Neomycin Sulfate, Polymyxin B SulfateIntervet, Inc.Dogs, CatsNADA 065-485
Robenz and BacifermBacitracin Zinc, Robenidine HydrochloridePhibro Animal Health Corp.ChickensNADA 096-933
Albac 50 Type A Medicated ArticleBacitracin ZincZoetis Inc.Swine, Chickens, TurkeysNADA 098-452
Amprol Hi-E and BacifermAmprolium, Bacitracin Zinc, EthopabatePhibro Animal Health Corp.ChickensNADA 114-794
CobanTM and AlbacBacitracin Zinc, MonensinPhibro Animal Health Corp.ChickensNADA 134-830
Bio-Cox and BacifermBacitracin Zinc, Salinomycin SodiumPhibro Animal Health Corp.ChickensNADA 139-235
Monteban and Albac; Monteban and BacifermBacitracin Zinc, NarasinPhibro Animal Health Corp.ChickensNADA 140-865
Avatec / BacifermBacitracin Zinc, LasalocidPhibro Animal Health Corp.ChickensNADA 141-083
Avatec / BacifermBacitracin Zinc, LasalocidPhibro Animal Health Corp.TurkeysNADA 141-109
Nicarb / BacifermBacitracin Zinc, NicarbazinPhibro Animal Health Corp.ChickensNADA 141-146
Avatec and AlbacBacitracin Zinc, LasalocidPhibro Animal Health Corp.TurkeysNADA 141-181
Baciferm / SacoxBacitracin Zinc, Salinomycin SodiumHuvepharma EOODChickensANADA 200-089
Albac / Bio-CoxBacitracin Zinc, Salinomycin SodiumPhibro Animal Health Corp.ChickensANADA 200-204
Albac / Amprol Hi-EAmprolium, Bacitracin Zinc, EthopabatePhibro Animal Health Corp.ChickensANADA 200-205
Sacox and AlbacBacitracin Zinc, Salinomycin SodiumPhibro Animal Health Corp.ChickensANADA 200-210
Robenz and AlbacBacitracin Zinc, Robenidine HydrochloridePhibro Animal Health Corp.ChickensANADA 200-212
Deccox and AlbacBacitracin Zinc, DecoquinatePhibro Animal Health Corp.ChickensANADA 200-213
Coyden and AlbacBacitracin Zinc, ClopidolPhibro Animal Health Corp.ChickensANADA 200-218
Albac 50 Type A Medicated ArticleBacitracin ZincZoetis Inc.Cattle, Swine, Chickens, TurkeysANADA 200-223
Albac 50 plus NicarbBacitracin Zinc, NicarbazinPhibro Animal Health Corp.ChickensANADA 200-478
Neomycin and Polymyxin B Sulfates, and Bacitracin Zinc Ophthalmic OintmentBacitracin Zinc, Neomycin Sulfate, Polymyxin B SulfateDomes Pharma S.A.Dogs, CatsANADA 200-553
Bonaid-Zinc Bacitracinapproval voluntarily withdrawnBacitracin Zinc, BuquinolateProctor & Gamble Pharmaceuticals, Inc.—NADA 035-314
Bonaid & Zinc Bacitracin & Penicillinapproval voluntarily withdrawnBacitracin Zinc, Buquinolate, Penicillin G ProcaineProctor & Gamble Pharmaceuticals, Inc.—NADA 035-315
Broiler Finisher Premix; Broiler Starter Premixapproval voluntarily withdrawnBacitracin Zinc, Roxarsone, ZoaleneRoche Vitamins, Inc.—NADA 040-395
Coyden 25 with Roxarsone and Bacitracin Zincapproval voluntarily withdrawnBacitracin Zinc, Clopidol, RoxarsoneHuvepharma EOODChickensNADA 044-016
3-Nitro / Deccox / Albacapproval voluntarily withdrawnBacitracin Zinc, Decoquinate, RoxarsoneZoetis Inc.ChickensNADA 091-326
Rainbow Broiler Base Concentrateapproval voluntarily withdrawnAmprolium, Bacitracin Zinc, EthopabateStockton Hay & Grain Co.ChickensNADA 091-646
Amprol HI-E / Baciferm / 3-Nitroapproval voluntarily withdrawnAmprolium, Bacitracin Zinc, Ethopabate, RoxarsoneZoetis Inc.ChickensNADA 105-758
3-Nitro-10 / Baciferm / Coban Premixapproval voluntarily withdrawnBacitracin Zinc, Monensin, RoxarsoneZoetis Inc.ChickensNADA 123-154
3-Nitro / Avatec / Bacifermapproval voluntarily withdrawnBacitracin Zinc, Lasalocid, RoxarsoneZoetis Inc.ChickensNADA 126-052
Anchor Zinc Bacitracinapproval voluntarily withdrawnBacitracin ZincPennfield Oil Co.ChickensNADA 128-550
Baciferm / Carb-O-Sepapproval voluntarily withdrawnBacitracin Zinc, CarbarsoneZoetis Inc.TurkeysNADA 136-484
3-Nitro / Albac / Bio-Coxapproval voluntarily withdrawnBacitracin Zinc, Roxarsone, Salinomycin SodiumZoetis Inc.ChickensNADA 137-536
3-Nitro / Albac / Cobanapproval voluntarily withdrawnBacitracin Zinc, Monensin, RoxarsoneZoetis Inc.ChickensNADA 138-703
3-Nitro / Bio-Cox / Bacifermapproval voluntarily withdrawnBacitracin Zinc, Roxarsone, Salinomycin SodiumZoetis Inc.ChickensNADA 139-190
Albac and Histostatapproval voluntarily withdrawnBacitracin Zinc, NitarsoneZoetis Inc.TurkeysNADA 141-132
3-Nitro / Albac / Sacoxapproval voluntarily withdrawnBacitracin Zinc, Roxarsone, Salinomycin SodiumHuvepharma EOODChickensANADA 200-086
3-Nitro / Baciferm / Sacoxapproval voluntarily withdrawnBacitracin Zinc, Roxarsone, Salinomycin SodiumHuvepharma EOODChickensANADA 200-143
Albac / Carb-O-Sepapproval voluntarily withdrawnBacitracin Zinc, CarbarsoneZoetis Inc.TurkeysANADA 200-203
3-Nitro / Albac / Deccoxapproval voluntarily withdrawnBacitracin Zinc, Decoquinate, RoxarsoneZoetis Inc.ChickensANADA 200-206
3-Nitro / Albac / Coyden 25approval voluntarily withdrawnBacitracin Zinc, Clopidol, RoxarsoneZoetis Inc.ChickensANADA 200-207
Avatec / 3-Nitro / Albacapproval voluntarily withdrawnBacitracin Zinc, Lasalocid, RoxarsoneZoetis Inc.ChickensANADA 200-208
3-Nitro / Albac / Sacoxapproval voluntarily withdrawnBacitracin Zinc, Roxarsone, Salinomycin SodiumZoetis Inc.ChickensANADA 200-209
3-Nitro / Albac / Cobanapproval voluntarily withdrawnBacitracin Zinc, Monensin, RoxarsoneZoetis Inc.ChickensANADA 200-211
3-Nitro / Albac / Amprol Hi-Eapproval voluntarily withdrawnAmprolium, Bacitracin Zinc, Ethopabate, RoxarsoneZoetis Inc.ChickensANADA 200-214
3-Nitro / Albac / Bio-Coxapproval voluntarily withdrawnBacitracin Zinc, Roxarsone, Salinomycin SodiumZoetis Inc.ChickensANADA 200-215
3-Nitro / Albac / Amprol Hi-Eapproval voluntarily withdrawnAmprolium, Bacitracin Zinc, Ethopabate, RoxarsoneZoetis Inc.ChickensANADA 200-217

Species are the major species the Green Book search lists for the application ("—" where it lists another species or none). Approval dates are not part of the Green Book listing files and are not shown. Pioneer applications (NADA) come first, then generics (ANADA).

Questions about bacitracin zinc reports

How many FDA adverse event reports mention bacitracin zinc?

81 reports through March 2026, 10 of them in the latest 12 months, counting bacitracin zinc alone and in combinations.

Which brands do these reports concern?

That cannot be known from the public data. openFDA masks brand and manufacturer names in adverse event records, so the reports counted here cannot be attributed to a particular brand. The Green Book reference list on this page names approved products containing bacitracin zinc without any counts.

In which combinations is bacitracin zinc reported?

Bacitracin Zinc (60.5% of these reports), Bacitracin Zinc + Neomycin Sulfate + Polymyxin B Sulfate (21% of these reports), Bacitracin Zinc + Polymyxin B Sulfate (16% of these reports), Bacitracin Zinc + Hydrocortisone (1.2% of these reports) and Bacitracin Zinc + Neomycin Sulfate (1.2% of these reports).

What reactions are reported for bacitracin zinc?

corneal ulcer (19.8%), ocular discharge (17.3%), vomiting (17.3%), diarrhoea (16%) and other abnormal test result NOS (16%). Shares are of reports naming the ingredient; one report can list several terms.

Which animals are these reports about?

dog (82.7%) and cat (13.6%).

Does a high count mean bacitracin zinc is a problem ingredient?

A count cannot show that. FDA states that "there is no certainty that the reported drug or device caused the adverse event" and that the event "may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources." Widely used ingredients collect more reports because more animals receive them.

How do I report a problem?

Call the drug company using the number on the label, or send Form FDA 1932a to FDA. See the guide on how to report.

Where this comes from. Counts are built from the openFDA Animal & Veterinary adverse event bulk files released 28 Sep 2026, which hold reports FDA's Center for Veterinary Medicine received through 31 Mar 2026. openFDA masks brand and manufacturer names in these files, so drugs are counted by the active ingredients each record discloses and no figure is attributed to a brand, application or company. Ingredient names, and the separate reference lists of approved products, follow the FDA Green Book as of 30 Sep 2026. Ingredient names follow the Green Book; salts and forms are kept as FDA lists them. Drug entries are matched by the active ingredients their unmasked ingredient field discloses. No report text, lot numbers or reporter details are published. See the methodology and sources; FDA's record is authoritative, and corrections are handled within five working days.