Pet Drug Reports

Reported signs

Reported sign · VeDDRA term

High blood pressure: reports listing this term

601reports listing the term, 2008–20260% of all reports
87reports, 12 months to March 202680 in the 12 months before
76.4%classed serious, as reportedall reports: 38.6%
71.9%of these reports concern dogscat 19.3%

"High blood pressure" is a coded term listed in 601 adverse event reports received by FDA, 0% of the database. Terms come from VeDDRA, the veterinary dictionary that FDA and drug companies use to code what a reporter describes.

87 reports listed it in the 12 months to March 2026, close to the 80 of the 12 months before. FDA posts reports quarterly with a delay of three to six months, so the newest months are incomplete and usually grow in later releases.

By active ingredient, the drugs named most often in those reports are trilostane, bedinvetmab and maropitant. That order mostly follows how many reports each has overall; the table gives the term's share within each drug's own reports as well.

71.9% of the reports concern dogs, 19.3% of the reports concern cats and 8.7% of the reports concern exposed people. Of reports listing this term that state seriousness, 76.4% were classed as serious; 13% record a death or euthanasia among the outcomes.

Drugs named most often in these reports, by active ingredient

Active ingredients recorded for the drugReports listing the termShare of that drug's own reports
Trilostane560.5%
Bedinvetmab550.3%
Maropitant450.3%
Milbemycin Oxime + Spinosad380%
Gabapentin360.3%
Carprofen300.1%
Prednisone240.3%
Fluralaner230%
Grapiprant230.3%
Butorphanol Tartrate220.3%
Buprenorphine200.3%
Frunevetmab200.3%
Pimobendan200.3%
Amlodipine192.6%
Ivermectin + Pyrantel Pamoate170%
Milbemycin Oxime + Praziquantel170.1%
Benazepril162.9%
Moxidectin160%
Oclacitinib160.1%
Pyrantel Pamoate + Sarolaner160%
Tilmicosin163.2%
Cefovecin sodium150.1%
Cyclosporine150.1%
Mirtazapine150.5%
Diphenhydramine140.3%

Ordered by number of reports, which mostly tracks how many reports a drug has overall. Across the whole database the term appears in 0% of reports. A drug's presence in a report means the animal received it, not that it produced the sign; FDA states that these data cannot be used to compare one product with another. openFDA masks brand and manufacturer names in adverse event records, so the reports counted here cannot be attributed to a particular brand.

Single ingredients, pooled across combinations

Active ingredientReports listing the termShare of the ingredient's own reports
Milbemycin Oxime600%
Trilostane560.5%
Bedinvetmab550.3%
Spinosad480%
Maropitant450.3%
Pyrantel Pamoate450%
Gabapentin360.3%
Moxidectin340%
Praziquantel340%
Carprofen300.1%
Sarolaner260%
Fluralaner250%
Prednisone240.3%
Grapiprant230.3%
Ivermectin230%
Butorphanol Tartrate220.3%
Amlodipine202.7%
Buprenorphine200.3%
Frunevetmab200.3%
Pimobendan200.3%
Benazepril173%
Oclacitinib160.1%
Tilmicosin163.2%
Cefovecin sodium150.1%
Cyclosporine150.1%

Species split

Dog71.9%432
Cat19.3%116
Human exposure8.7%52
Cattle0.2%1

Coloured bar: share of reports listing this term. Grey bar: the species' share of all reports. The term appears in 0% of all dog reports; The term appears in 0.1% of all cat reports.

Trend

0713Apr 2021: 3May 2021: 3Jun 2021: 3Jul 2021: 5Aug 2021: 2Sep 2021: 3Oct 2021: 1Nov 2021: 1Dec 2021: 5Jan 2022: 52022Feb 2022: 1Mar 2022: 4Apr 2022: 2May 2022: 3Jun 2022: 4Jul 2022: 2Aug 2022: 8Sep 2022: 0Oct 2022: 4Nov 2022: 6Dec 2022: 7Jan 2023: 12023Feb 2023: 5Mar 2023: 5Apr 2023: 7May 2023: 4Jun 2023: 4Jul 2023: 2Aug 2023: 9Sep 2023: 6Oct 2023: 5Nov 2023: 8Dec 2023: 7Jan 2024: 62024Feb 2024: 8Mar 2024: 7Apr 2024: 6May 2024: 9Jun 2024: 9Jul 2024: 9Aug 2024: 7Sep 2024: 6Oct 2024: 2Nov 2024: 7Dec 2024: 8Jan 2025: 62025Feb 2025: 4Mar 2025: 7Apr 2025: 12May 2025: 12Jun 2025: 12Jul 2025: 13Aug 2025: 5Sep 2025: 5Oct 2025: 4Nov 2025: 5Dec 2025: 5Jan 2026: 82026Feb 2026: 4Mar 2026: 2

Reports by month FDA received them, five years to March 2026. The newest months are incomplete because FDA posts reports with a delay of three to six months.

045902008: 220082011: 62012: 2120122013: 202014: 2120142015: 312016: 2020162017: 372018: 2920182019: 412020: 3920202021: 372022: 4620222023: 632024: 8420242025: 902026: 142026

Outcomes and ages in these reports

Outcome recorded in the report

Recovered/Normal20%120
Recovered with Sequela2.3%14
Ongoing36.6%220
Died3%18
Euthanized10%60
Outcome Unknown28.8%173

Age of the animal

Under 1 year2%12
1 to 3 years10.5%63
4 to 7 years16.8%101
8 to 11 years25.6%154
12 years and over40.6%244
Age not given4.5%27
MeasureReports listing this termAll reports
Reports6011,357,245
Classed serious, of reports stating it76.4%38.6%
Death or euthanasia recorded, per 1,000 reports129.863.8

Grey bars and the right-hand column are the whole database. Outcomes are as stated by the reporter and describe the report as a whole, not this term alone.

Questions about "High blood pressure"

What does "High blood pressure" mean in an adverse event report?

It is a VeDDRA dictionary term picked to code what the reporter described. The report's free-text description is not published by FDA and is not shown here.

How many reports list high blood pressure?

601 reports through March 2026 (0% of all reports), 87 of them in the latest 12 months.

Which drugs are named most often alongside this term?

By active ingredient: trilostane (56), bedinvetmab (55), maropitant (45), milbemycin oxime + spinosad (38) and gabapentin (36). Drugs with many reports overall lead almost every term's list. Brands cannot be identified: openFDA masks them.

Which species are involved?

dog (71.9%), cat (19.3%), human exposure (8.7%) and cattle (0.2%).

Does a drug appearing here mean it produced this sign?

No such conclusion can be drawn. FDA states that "there is no certainty that the reported drug or device caused the adverse event" and that the event "may have been related to an underlying disease, other drugs used at the same time or other non-drug related sources."

My animal shows this sign. What now?

This site cannot assess an animal. A veterinarian can; for an emergency, contact a veterinary emergency clinic. See the guide on when to call a vet.

Where this comes from. Counts are built from the openFDA Animal & Veterinary adverse event bulk files released 28 Sep 2026, which hold reports FDA's Center for Veterinary Medicine received through 31 Mar 2026. openFDA masks brand and manufacturer names in these files, so drugs are counted by the active ingredients each record discloses and no figure is attributed to a brand, application or company. Ingredient names, and the separate reference lists of approved products, follow the FDA Green Book as of 1 Oct 2026. Spelling variants of the same VeDDRA term (for example with and without a cross-reference note) are pooled. No report text, lot numbers or reporter details are published. See the methodology and sources; FDA's record is authoritative, and corrections are handled within five working days.